Programme
THURSDAY 19TH MAY 2022 |
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13:30 – 14:30 |
Student & Postdoc Networking Reception |
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14:30 – 15:20 |
Registration & Welcome Reception |
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Keynote and Emerging Topics Session |
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15:20 – 15:30 |
Opening Comments |
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15:30 – 16:05 |
Keynote Presentation Edward Morrisey |
CELLULAR AND MOLECULAR MECHANISMS UNDERLYING LUNG HOMEOSTASIS AND REGENERATION |
16:05 – 16:30 |
Matthew Thomas |
STRATEGIC APPROACH TO PF-ILD DRUG DISCOVERY: INNOVATION THROUGH ‘DIFFERENTIAL PATIENT BIOLOGY’ |
16:30 – 16:45 |
Masahiro Yoshida |
EPITHELIAL AND IMMUNE RESPONSES TO SARS-COV-2 DURING POSTNATAL DEVELOPMENT IN CHILDREN VERSUS ADULTS |
16:45 – 17:15 |
Refreshments & Poster Viewing |
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Emerging topics: Monogenic Lung Diseases |
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17:15 – 17:40 |
Xin Sun |
LUNG INTEROCEPTION: HOW THE LUNG SENSE AND RESPOND TO CUES |
17:40 – 18:05 |
David Schwartz |
IDIOPATHIC PULMONARY FIBROSIS: A GENETIC AND EPIGENETIC DISEASE INITIATED BY MUC5B |
18:05– 18:20 |
Aaron Zorn |
THE CLEAR CONSORTIUM: DISCOVERING THE DEVELOPMENTAL BASIS OF TRACHEA-ESOPHAGEAL BIRTH DEFECTS |
18:20 – 18:45 |
David Ornitz |
FIBROBLAST GROWTH FACTOR 18 (FGF18) REGULATION OF POSTNATAL LUNG DEVELOPMENT |
18:45 |
Group Dinner |
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FRIDAY 20TH MAY 2022 |
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07:00 – 08:30 |
Buffet Breakfast |
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Mechanotransduction In Lung Development and Fibrosis. |
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08:30 – 08:55 |
Wellington Cardoso |
ONTOGENY AND PLASTICITY OF THE AIRWAY STEM CELL COMPARTMENT IN DEVELOPMENT AND DISEASE |
08:55 – 09:20 |
Purushothama Rao Tata |
HUMAN DISTAL LUNG CELL DYNAMICS IN HEALTH AND DISEASE |
09:20 – 09:45 |
Daniel Tschumperlin |
DOPAMINE SIGNALING IN FIBROSIS RESOLUTION |
09:45 – 10:10 |
Jin-Ah Park |
COLLECTIVE EPITHELIAL CELL MIGRATION BY THE UNJAMMING TRANSITION (UJT) IN THE ABSENCE OF THE EPITHELIAL–MESENCHYMAL TRANSITION (EMT) |
10:10 – 10:40 |
Refreshments & Poster Viewing |
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10:40 – 11:05 |
Dean Sheppard |
PULMONARY FIBROBLAST HETEROGENEITY IN HEALTH AND DISEASE |
11:05 – 11:20 |
Rachel Warren |
LUNG STEM CELLS AND THEIR NICHES |
11:20 – 11:35 |
Robbert Rottier |
DISTINCT ROLES FOR SOX2 AND SOX21 IN DIFFERENTIATION, DISTRIBUTION AND MATURATION OF PULMONARY NEUROENDOCRINE CELLS |
11:35 – 11:50 |
Katharine Goodwin |
PLASTICITY IN AIRWAY SMOOTH MUSCLE DIFFERENTIATION DURING MOUSE LUNG DEVELOPMENT |
11:50 - 12:05 |
SeungHye Han |
MITOCHONDRIAL NAD+ REGENERATION CONTROLS ALVEOLAR EPITHELIAL CELL FATE THROUGH THE INTEGRATED STRESS RESPONSE |
12:05 – 17:00 |
Lunch at Leisure & Free Time |
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Novel Models of IPF |
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17:00 – 17:25 |
Melanie Koenigshoff |
LUNG EPITHELIAL CELLS AND THE FIBROTIC NICHE |
17:25 – 17:50 |
Timothy Blackwell |
GENETIC LANDSCAPE OF FAMILIAL PULMONARY FIBROSIS |
17:50 – 18:15 |
Darrell Kotton |
PLURIPOTENT STEM CELLS TO MODEL AND TREAT LUNG DISEASE |
18:15 – 18:40 |
Susanne Herold |
SINGLE CELL RNA SEQUENCING AND LUNG ORGANOID MODELS REVEAL NOVEL MECHANISMS OF MACROPHAGE-EPITHELIAL INTERACTIONS DURING LUNG REPAIR |
18:40 – 18:55 |
Cara J. Gottardi |
LUNG INJURY INDUCES ALVEOLAR TYPE 2 CELL HYPERTROPHY AND POLYPLOIDY WITH IMPLICATIONS FOR REPAIR AND REGENERATION |
18:55 – 19:10 |
Tatiana Kalin |
SINGLE CELL RNA SEQUENCING IDENTIFIES ENDOTHELIAL TRANSCRIPTION FACTORS INHIBITING LUNG FIBROSIS. |
19:10 – 20:10 |
Poster Session 1 & Refreshments |
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20:10 |
Dinner at Leisure |
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SATURDAY 21ST MAY 2022 |
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07:00 – 08:30 |
Buffet Breakfast |
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Stem Cell Niche Interactions in Lung Health and Disease |
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08:30 – 08:55 |
Tushar Desai |
CARTOGRAPHY OF DYNAMIC WNT SIGNALING IN IPF |
08:55 - 09:20 |
Ana Pardo-Saganta |
DECIPHERING NOVEL EPITHELIAL-MESENCHYMAL INTERACTIONS INVOLVED IN PULMONARY FIBROSIS |
09:20 - 09:45 |
Jianwen Que |
RUNX2-CENTERED TRANSCRIPTION PROGRAM PROMOTES MYOFIBROBLAST DIFFERENTIATION OF LEPR+ MESENCHYMAL POPULATION DURING PULMONARY FIBROSIS. |
09:45 - 10:30 |
Group Photo, Refreshments & Poster Viewing |
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10:30 – 10:55 |
Tien Peng |
FUNCTIONAL CHARACTERIZATION OF SENESCENT CELLS IN THE LUNG STEM CELL NICHE. |
10:55 – 11:10 |
Yuru Liu |
REGULATION OF ALVEOLAR TYPE II CELLS DURING LUNG HOMEOSTASIS AND REPAIR |
11:10 – 11:35 |
Barry Stripp |
EPITHELIAL PLASTICITY AND INNATE IMMUNE ACTIVATION PROMOTE LUNG TISSUE REMODELING FOLLOWING RESPIRATORY VIRAL INFECTION |
11:35 – 11:50 |
Discussion on the future of this Fusion meeting |
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12:25 – 17:10 |
Lunch at Leisure & Free Time |
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Pathways regulating Lung Development |
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17:10 - 17:25 |
Jaymin Kathiriya |
HUMAN ALVEOLAR TYPE 2 EPITHELIUM TRANSDIFFERENTIATES INTO METAPLASTIC KRT5+ BASAL CELLS |
17:25 – 17:50 |
Debora Sinner |
MOLECULAR AND CELLULAR MECHANISMS MEDIATING DIFFERENTIATION OF THE LARGE AIRWAYS |
17:50 – 18:15 |
Parviz Minoo |
“UNDER CONSTRUCTION, ALVEOLAR EPITHELIAL NICHE”: IMPLICATIONS FOR REGENERATIVE CAPACITY IN IMMATURE LUNGS |
18:15 – 18:40 |
Jason Spence |
EPITHELIAL-MESENCHYMAL INTERACTIONS GOVERNING PROGENITOR CELL FATE IN THE DEVELOPING HUMAN LUNG |
18:40 – 18:55 |
Sarah Paramore |
MESENCHYMAL VANGL1/2 DRIVES SACCULATION IN THE EMBRYONIC MOUSE LUNG |
18:55 – 20:00 |
Poster Session 2 & Refreshments |
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20:00 |
*Gala Dinner & Poster Awards* |
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SUNDAY 22ND MAY 2022 |
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07:00 – 08:30 |
Buffet Breakfast |
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Aging and Lung Fibrosis |
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08:30 – 08:55 |
Gisli Jenkins |
UNDERSTANDING PULMONARY FIBROSIS IN THE POST COVID WORLD |
08:55 – 09:20 |
Mike O’Reilly |
NEONATAL HYPEROXIA STIMULATES EXPRESSION OF THE PROLIFERATION MARKER KI67 IN ALVEOLAR EPITHELIAL TYPE 1 CELLS. WHAT IS GOING ON HERE? |
09:20 – 09:45 |
Brent Carter |
THERAPEUTIC TARGETING APOPTOSIS RESISTANCE TO REVERSE ESTABLISHED FIBROSIS. |
09:45 – 10:15 |
Refreshments |
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10:15 – 10:40 |
Victor Thanncikal |
CELLULAR BIOENERGETICS IN EPITHELIAL MESENCHYMAL INTERACTIONS |
10:40 – 11:05 |
Tanyalak Parimon |
SYNDECAN-1 ACCELERATES EPITHELIAL CELL SENESCENCE TO PROMOTE LUNG FIBROSIS |
11:05 – 11:20 |
Cory Wilson |
SINE OCULIS HOMEOBOX HOMOLOG 1 (SIX1) PLAYS A CRITICAL ROLE IN LUNG FIBROSIS |
11:20 – 11:30 |
Closing Comments |