Past Conference

2nd Neuroepigenetics & Neuroepitranscriptomics Conference

#Neuroepi20

Date

03 Mar - 06 Mar 2020

Location

Nassau, Bahamas

Early Bird - Expired  •  Talk Submission - Expired  •  Poster Submission - Expired  •  Registration & Payment Deadline - Expired

Synopsis

Epigenetic mechanisms - including DNA and histone modifications, as well as regulation by non-coding RNAs - have pivotal roles in the nervous system. Aberrant epigenetic regulation also contributes to pathogenesis in various brain disorders. There are a number of recent ground-breaking discoveries of new features of epigenetic marks and regulation that are enriched in the nervous system, leading to an emerging new field of “neuroepigenetics”. In addition, new discoveries of modification of mRNAs and long non-coding RNAs lead to a new field of “epitranscriptomics”. This meeting will bring together experts and pioneers in studying neuroepigenetics and epitranscriptomics to provide an up-to-date and comprehensive picture of epigenetic and epitranscriptomic mechanisms in neural development, reprogramming and cell identity, plasticity, neuronal function and dysfunction. The meeting will offer opportunity for interdisciplinary interactions and future collaborations.

Key Sessions:

  • Epigenetic mechanisms regulating brain development and stem cells 
  • Transcriptional and translational regulation
  • Neuronal specific splicing
  • Brain developmental disorders, aging and neurodegeneration
  • Single-cell transcriptome and epigenome analysis
  • Genome-wide analysis of different DNA and RNA modifications
  • 3D epigenome and chromatin topology

Student Offer

Take advantage of this fantastic opportunity for students! Register an academic and bring a student for only $850. Unfortunately, Postdocs are not eligible for this offer. Both registration packages include; accommodation for the 03, 04, 05 March 2020 (on a shared basis for students) and a 24hour all-inclusive food and beverage package for the conference period. Once registered, please contact Jack Peters to obtain a special registration link for your student.

Confirmed Plenary Speakers

Shelley Berger (University of Pennsylvania)
HISTONE ACETYLATION PATHWAYS IN LEARNING AND MEMORY
Gonçalo Castelo-Branco (Karolinska Institutet)
SINGLE-CELL TRANSCRIPTOMICS AND EPIGENOMICS REVEAL DISEASE-SPECIFIC STATES OF OLIGODENDROGLIA IN MULTIPLE SCLEROSIS
Joseph Ecker (Salk Institute)
DNA METHYLATION LANDSCAPE OF THE MOUSE BRAIN AT SINGLE CELL RESOLUTION
Johannes Gräff (EPFL)
Michael Greenberg (Harvard Medical School)
HOW NATURE AND NURTURE CONSPIRE TO CONTROL BRAIN DEVELOPMENT AND FUNCTION
Rudolf Jaenisch (MIT)
EPIGENETIC EDITING AND THERAPEUTIC APPROACHES TO AUTISM
Manolis Kellis (MIT)
SINGLE-CELL EPIGENOMIC AND TRANSCRIPTOMIC DISSECTION OF PSYCHIATRIC AND NEURODEGENERATIVE DISORDERS
Eric Nestler (Icahn School of Medicine at Mount Sinai)
EPIGENETIC AND TRANSCRIPTIONAL MECHANISMS OF DRUG ADDICTION

Confirmed Invited Speakers

Angel Barco (Instituto de Neurociencias, UMH-CSIC)
EPIGENOMIC SIGNATURE OF NEURONAL ACTIVATION IN HIPPOCAMPAL CIRCUITS
Timothy Bredy (Queensland Brain Institute)
LONG NONCODING RNAs AND MEMORY
Andre Fischer (University Medical Center Göttingen)
EPIGENETIC THERAPIES FOR CNS DISEASES

Harrison Gabel (Washington University School of Medicine)
UNDERSTANDING THE UNIQUE NEURONAL METHYLOME
Yukiko Gotoh (The University of Tokyo)
EPIGENETIC REGULATION OF NEURAL STEM-PROGENITOR CELL FATE IN THE DEVELOPING MOUSE NEOCORTEX
Elizabeth A Heller (University of Pennsylvania)
CHROMATIN-MEDIATED ALTERNATIVE SPLICING REGULATES COCAINE REWARD BEHAVIOR
Andrew Jaffe (The Lieber Institute)
LEVERAGING HUMAN BRAIN TISSUE TO BETTER UNDERSTAND SCHIZOPHRENIA
Peng Jin (Emory University)
EPIGENETIC DYNAMICS IN NEURODEGENERATIVE DISORDERS
Tristan Qingyun Li (Washington University in St. Louis)
DISSECTING THE DEVELOPMENTAL HETEROGENEITY OF MICROGLIA
Kate Meyer (Duke University School of Medicine)
DETECTING MRNA METHYLATION AND ITS ROLE IN GENE EXPRESSION
Kinichi Nakashima (Kyushu University)
ARTIFICIAL NEUROGENESIS IN THE ADULT CENTRAL NERVOUS SYSTEMS AND ITS EFFECTS ON FUNCTIONAL RECOVERY AFTER INJURY
Andreas Pfenning (Carnegie Mellon University)
CELL TYPE-SPECIFIC TRANSCRIPTOME AND CHROMATIN ACCESSIBILITY ABNORMALITIES IN DOPAMINE DEPLETED MICE
Sika Zheng (University of California Riverside)
THE EMERGING ROLES OF NEURON-SPECIFIC ALTERNATIVE SPLICING PROGRAMMING

Confirmed Speakers

Invited Speakers
Angel Barco

Angel Barco

CSIC Research Professor, Instituto de Neurociencias (CSIC-UMH)

Harrison Gabel

Harrison Gabel

Associate Professor, Washington University School of Medicine

Peng Jin

Peng Jin

Professor and Chair, Emory University

Kinichi Nakashima

Kinichi Nakashima

Professor, Graduate School of Medical Sciences, Kyushu University

Sika Zheng

Sika Zheng

Associate Professor, University of California Riverside

Timothy Bredy

Timothy Bredy

Professor, Queensland Brain Institute

Kate Meyer

Kate Meyer

Assistant Professor, Duke University School of Medicine

Jessica Tollkuhn

Jessica Tollkuhn

Assistant Professor, Cold Spring Harbor Laboratory

Andreas Pfenning

Andreas Pfenning

Assistant Professor, Carnegie Mellon University

Elizabeth Heller

Elizabeth Heller

Assistant Professor, University of Pennsylvania

Andrew Jaffe

Andrew Jaffe

Lead Investigator, Lieber Institute for Brain Development

Yukiko Gotoh

Yukiko Gotoh

Professor, The University of Tokyo

Andre Fischer

Andre Fischer

Site speaker, German Center for Neurodegenerative Diseases (DZNE) e.V.

Tristan Qingyun Li

Tristan Qingyun Li

Assistant Professor, Washington University School of Medicine in St. Louis

Programme

TUESDAY 3RD MARCH 2020

14:15 – 15:15

Student Networking Lunch

 

15:00 – 16:00

Registration & Welcome Reception

 

Session 1
Andrew Jaffe

16:00 – 16:10

Opening Comments

 

16:10 – 17:00

Shelley Berger
University of Pennsylvania

HISTONE ACETYLATION PATHWAYS IN LEARNING AND MEMORY

 

17:00 – 17:30

Angel Barco
Instituto de Neurociencias, UMH-CSIC

EPIGENOMIC SIGNATURE OF NEURONAL ACTIVATION IN HIPPOCAMPAL CIRCUITS

 

17:30 – 18:15

Refreshments

 

18:15 – 18:30
 

Yue Feng
Emory University

THE QKI-CIRCULAR RNA PATHWAY ENHANCES HUMAN OLIGODENDROGLIA DIFFERENTIATION

 

18:30 – 19:00

Timothy Bredy Queensland Brain Institute

LONG NONCODING RNAs AND MEMORY

 

19:00 – 19:40

Meet the Poster Presenters

 

19:45

Dinner

 

WEDNESDAY 4TH MARCH 2020

07:00 – 08:30

Buffet Breakfast *The Market Place Restaurant*
 

Session 2
Eric Nestler

08:30 – 09:00

Gonçalo Castelo-Branco Karolinska Institutet

SINGLE-CELL TRANSCRIPTOMICS AND EPIGENOMICS REVEAL DISEASE-SPECIFIC STATES OF OLIGODENDROGLIA IN MULTIPLE SCLEROSIS

09:00 – 09:15

Ramen Saha
University of California, Merced

TWO FUNCTIONALLY DISTINCT SIGNALING CASCADES EFFICIENTLY COUPLE NEURONAL ACTIVITY WITH IMMEDIATE EARLY GENE TRANSCRIPTION

09:15 – 09:45

Joseph Ecker
Salk Institute

DNA METHYLATION LANDSCAPE OF THE MOUSE BRAIN AT SINGLE CELL RESOLUTION

09:45 – 10:15

André Fischer
University Medical Center Göttingen

EPIGENETIC THERAPIES FOR CNS DISEASES

10:15 – 11:00

Group Photo, Refreshments & Poster Viewing

11:00 – 11:30

Harrison Gabel Washington University School of Medicine

UNDERSTANDING THE UNIQUE NEURONAL METHYLOME

11:30 – 12:00

Yukiko Gotoh
The University of Tokyo

EPIGENETIC REGULATION OF NEURAL STEM-PROGENITOR CELL FATE IN THE DEVELOPING MOUSE NEOCORTEX

12:00 – 12:30

Johannes Gräff
EPFL

EPIGENETIC PRIMING OF MEMORY FORMATION

12:30 – 16:45

Lunch & Free Time

Session 3
Yukiko Gotoh

16:45 – 17:15

Michael Greenberg Harvard Medical School

HOW NATURE AND NURTURE CONSPIRE TO CONTROL BRAIN DEVELOPMENT AND FUNCTION

17:15 – 17:45

Manolis Kellis
MIT

SINGLE-CELL EPIGENOMIC AND TRANSCRIPTOMIC DISSECTION OF PSYCHIATRIC AND NEURODEGENERATIVE DISORDERS

17:45 – 19:45

Poster Session & Refreshments

19:45

Dinner

THURSDAY 5TH MARCH 2020

07:00 – 08:30

Buffet Breakfast *The Market Place Restaurant*
 

Session 4
Li-Huei Tsai

08:30 – 09:00

Elizabeth A Heller University of Pennsylvania

CHROMATIN-MEDIATED ALTERNATIVE SPLICING REGULATES COCAINE REWARD BEHAVIOR

09:00 – 09:15

Nael Nadif Kasri
Donders Institute for Brain Cognition and Behaviour

A ROLE FOR KANSL1 IN THE REGULATION OF AUTOPHAGY-RELATED GENE TRANSCRIPTION BY H4K16 ACETYLATION IN HUMAN DERIVED NEURONS

09:15 – 09:45

Rudolf Jaenisch
MIT

EPIGENETIC EDITING AND THERAPEUTIC APPROACHES TO AUTISM

09:45 – 10:30

Refreshments & Poster Viewing

10:30 – 11:00
 

Andrew Jaffe
The Lieber Institute

LEVERAGING HUMAN BRAIN TISSUE TO BETTER UNDERSTAND SCHIZOPHRENIA

11:00 – 11:30

Peng Jin
Emory University

EPIGENETIC DYNAMICS IN NEURODEGENERATIVE DISORDERS

11:30 – 11:45
 

Ashley Webb
Brown University

DECODING CHROMATIN ACCESSIBILITY DYNAMICS DURING NEURAL STEM CELL ACTIVATION

11:45 – 16:30

Lunch & Free Time

Session 5
Johannes Gräff

16:30 – 17:00

Caroline Vissers
Johns Hopkins University School of Medicine

EPITRANSCRIPTOMIC REGULATION IN THE NERVOUS SYSTEM

17:00 – 17:30

Tristan Qingyun Li
Washington University in St. Louis

DISSECTING THE DEVELOPMENTAL HETEROGENEITY OF MICROGLIA

17:30 – 17:45

Gilda Stefanelli
University of Toronto Mississauga

THE HISTONE VARIANT MACROH2A.1, BUT NOT MACROH2A.2, PLAYS A MAJOR ROLE IN LEARNING-INDUCED GENE EXPRESSION AND MEMORY FORMATION IN MICE

17:45 – 18:30

Refreshments & Poster Viewing

18:30 – 19:00

Kate Meyer
Duke University School of Medicine

DETECTING MRNA METHYLATION AND ITS ROLE IN GENE EXPRESSION

19:00 – 19:30

Kinichi Nakashima Kyushu University

ARTIFICIAL NEUROGENESIS IN THE ADULT CENTRAL NERVOUS SYSTEMS AND ITS EFFECTS ON FUNCTIONAL RECOVERY AFTER INJURY

19:30 – 20:00

Eric Nestler
Icahn School of Medicine at Mount Sinai

EPIGENETIC AND TRANSCRIPTIONAL MECHANISMS OF DRUG ADDICTION

20:00

Gala Dinner & Poster Awards

FRIDAY 6TH MARCH 2020

07:00 – 08:30

Buffet Breakfast at *The Market Place Restaurant*

Session 6
Elizabeth A Heller

08:30 – 09:00

Li-Huei Tsai
MIT

SINGLE CELL TRANSCRIPTOMIC DISSECTION OF HYPOTHALAMIC NUCLEI IN MOUSE AND HUMANS

09:00 – 09:30

Andreas Pfenning Carnegie Mellon University

CELL TYPE-SPECIFIC TRANSCRIPTOME AND CHROMATIN ACCESSIBILITY ABNORMALITIES IN DOPAMINE DEPLETED MICE

09:30 – 10:00

Refreshments

10:00 – 10:30
 

Jessica Tollkuhn
Cold Spring Harbor Laboratory

GENE REGULATION BY ESTROGEN IN A SEXUALLY DIMORPHIC BRAIN AREA

10:30 – 11:00
 

Sika Zheng
University of California Riverside

THE EMERGING ROLES OF NEURON-SPECIFIC ALTERNATIVE SPLICING PROGRAMMING

11:00 – 11:10

Closing Comments

Supported by

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Venue & Location

Melia Nassau Beach All Inclusive

Overlooking one of the finest beaches in the world the Meliá Nassau Beach is surrounded by crystal blue waters and white sandy beaches. Located on the stunning Cable Beach, you are just a few minutes walk from the center, shops and restaurants. The beautiful Nassau Botanical Gardens are within easy reach (7km) and Lynden Pindling International Airport is situated only 9km away.

Throughout your stay delegates will enjoy a full meal plan, inclusive of beverages. Take your pick from Cilantro where you can experience the natural textures, aromas and flavors of Mexico, Nikkei, celebrated for its exquisite fusion of Japanese, Cantonese and Peruvian cuisine featuring a sushi bar and Teppanyaki tables, Estavida, an upbeat tapas lounge located in the hotel lobby serving innovative tapas and a wide selection of cocktails, Aqua, an A la carte restaurant specializing in exquisite, rustic Italian cuisine, The Market Place, where you will find an International buffet serving an array of exquisite dishes, O'Grille, an open air restaurant with fabulous views of the sea and pool serving casual beach fare and light bites and finally The Black Angus, a steakhouse featuring hip, contemporary jazz and modern decor, offering guests the finest quality prime cuts and the freshest ingredients.(This restaurant is not included in the all inclusive package, additional charges apply). The Gala Night takes place on the third evening of the conference with a mouth-watering feast of local cuisine, an open bar and amazing local entertainment.  We welcome all delegates and their accompanying persons to the Gala Night – a truly fun filled night not to be missed!

Hotel Facilities

  • 24 hour reception
  • Room service
  • 3 heated outdoor pools
  • Complimentary resort wide Wi-Fi (guest rooms, throughout hotel, beach and conference areas)   
  • 24-hour Fitness Center
  • 7 dining venues
  • 4 bars.
  • non-motorised water sports

The Bahamas is formed by over 700 islands, keys and islets located in the Atlantic Ocean and renowned for its warm sunshine, mild climate, fine, white sandy beaches, turquoise, crystal clear water and friendly people, making this the perfect environment to relax and unwind in your free time during the conference.

General Information

Venue Rating

★ ★ ★ ★

Currency

US Dollar (USD)

Address

Nassau W Bay St. Nassau Bahamas

Nearest Airport

Lynden Pindling International Airport

Location

The Melia Nassau Beach All-Inclusive is located right on the stunning Cable Beach just a few minutes away from the airport and city center; Nearby in Downtown Nassau you can experience the flavours of new foods at local restaurants, shop 'til you drop at Straw market or take a trip through time at the Pirates Museum. The beautiful Nassau Botanical Gardens are close by and water enthusiasts can enjoy non-motorized water sports right on property.

Nassau is the capital of the Bahamas. It lies on the island of New Providence, with neighboring Paradise Island accessible via Nassau Harbor bridges. The city has a hilly landscape and is known for it's fabulous beaches as well as its offshore coral reefs, popular for diving and snorkeling. It retains many of its typical pastel-colored British colonial buildings, like the pink-hued Government House.

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Conference Manager

Jack Peters

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+44 (0) 1638 555057

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