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Neuroepigenetics & Neuroepitranscriptomics Conference
24 Feb - 27 Feb 2018
Cancun, Mexico
Early Bird - Expired • Talk Submission - Expired • Poster Submission - Expired • Registration & Payment Deadline - Expired
Synopsis
Epigenetic mechanisms — including DNA and histone modifications, as well as regulation by non-coding RNAs — have pivotal roles in the nervous system. Aberrant epigenetic regulation also contributes to pathogenesis in various brain disorders. There are a number of recent ground-breaking discoveries of new features of epigenetic marks and regulation that are enriched in the nervous system, leading to an emerging new field of “neuroepigenetics”. In addition, new discoveries of modification of mRNAs and long non-coding RNAs lead to a new field of “epitranscriptomics”. This meeting will bring together experts and pioneers in studying neuroepigenetics and epitranscriptomics to provide an up-to-date and comprehensive picture of epigenetic and epitranscriptomic mechanisms in neural development, reprogramming and cell identity, plasticity, neuronal function and dysfunction. The meeting will offer opportunity for interdisciplinary interactions and future collaborations.
Key Sessions:
- Epigenetic mechanisms regulating brain development and stem cells
- Transcriptional and translational regulation
- Neuronal specific splicing
- Brain developmental disorders, aging and neurodegeneration
- Single-cell analysis
- Genome-wide analysis of different DNA and RNA modifications
- 3D epigenome and chromatin topology
Student Offer
Take advantage of this fantastic opportunity for students! Register an academic at the standard rate of $1,798 and bring a student for only $745. Unfortunately, Postdocs are not eligible. Both registration packages include; accommodation for the 24, 25, 26 February 2018 (on a shared basis for students, note guest rooms are open plan) and a 24hour all-inclusive food and beverage package for the conference period. Once registered, please contact Jack Peters (jack@fusion-conferences.com) to obtain a special registration link for your student.
Plenary Speakers
Anne Brunet (Stanford University)
Michael Greenberg (Harvard University)
Chuan He (The University of Chicago)
RNA METHYLATION IN GENE EXPRESSION REGULATION
Rudolf Jaenisch (Whitehead Institute)
EPIGENETIC REGULATION, STEM CELLS AND DISEASE RELEVANCE
Peng Jin (Emory University)
DYNAMIC CHEMICAL MODIFICATIONS OF NUCLEIC ACID IN NEURODEVELOMENT AND DISEASES
Guo-li Ming (University of Pennsylvania)
Eric Nestler (Icahn School of Medicine at Mount Sinai)
TRANSCRIPTIONAL AND EPIGENETIC MECHANISMS OF ADDICTION
Andreas Pfenning (Carnegie Mellon University)
EPIGENOMIC DISSECTION OF REGULATORY ELEMENTS UNDERLYING THE EVOLUTION OF LEARNED VOCAL BEHAVIOR
Antonella Riccio (University College London)
THE SECRET LIFE OF 3’UTRS IN DEVELOPING NEURONS
Invited Speakers
Angel Barco (Instituto de Neurociencias)
ROLE OF KAT3 PROTEINS IN NEUROPLASTICITY AND NEURONAL IDENTITY
Timothy Bredy (Queensland Brain Institute)
THE WHO, WHAT, WHERE, WHY AND HOW OF NEW DNA MODIFICATIONS IN THE BRAIN AND THEIR ROLE IN MEMORY
Alon Chen (Weizmann Institute of Science & Max-Planck Institute of Psychiatry)
THE ROLE OF M6A-RNA METHYLATION IN STRESS RESPONSE REGULATION
Jesse Gray (Harvard Medical School)
DISTINCT NEURONAL ACTIVITY PATTERNS INDUCE DIFFERENT GENE EXPRESSION PROGRAMS
Elizabeth A. Heller (Perelman School of Medicine)
CHROMATIN-MEDIATED ALTERNATIVE SPLICING IN REWARD PATHOPHYSIOLOGY
Andrew Jaffe (Lieber Institute for Brain Development)
DYNAMIC DNA METHYLATION ACROSS DEVELOPMENT, GENOTYPE AND MENTAL ILLNESS IN THE HUMAN BRAIN
Tae-Kyung Kim (UT Southwestern Medical Center)
ACTIVITY-REGULATED TRANSCRIPTIONAL ENHANCERS
Ram Madabhushi (UT Southwestern Medical Center)
THE ROLE OF ACTIVITY-INDUCED DNA BREAKS IN NEURONAL PHYSIOLOGY, LEARNING AND MEMORY
Anne Schaefer (Mount Sinai School of Medicine)
EPIGENETIC CONTROL OF BRAIN REGION-SPECIFIC MICROGLIA CLEARANCE ACTIVITY BY PRC2
Yanhong Shi (City of Hope)
m6A RNA METHYLATION REGULATES NEURAL DEVELOPMENT AND NEUROLOGICAL DISORDER
Anne West (Duke Institute for Brain Sciences)
EPIGENOME EDITING IN NEURONS WITH dCAS9 FUSION PROTEINS
Heng Zhu (Johns Hopkins University)
DNA METHYLATION-DEPENDENT KLF4 BINDING PROMOTES TRANSCRIPTION ACTIVATION AND CHROMATIN REMODELING
Confirmed Speakers
Chairs
Plenary Speakers
Antonella Riccio
Professor , MRC LMCB Univ. College London
Eric Nestler
Nash Family Professor Neuroscience, Icahn School of Medicine at Mount Sinai
Peng Jin
Professor and Chair, Emory University
Chuan He
Professor, The University of Chicago/HHMI
Guo-li Ming
Professor, University of Pennsylvania
Michael Greenberg
Department Chair and the Nathan Marsh Pusey Professor of Neurobiology, Harvard Medical School
Rudolf Jaenisch
Member, WIBR and Professor of Biology, M.I.T., Whitehead Institute for Biomedical Research
Anne Brunet
Michele and Timothy Barakett Professor of Genetics, Stanford University
Invited Speakers
Jesse Gray
Assistant Professor, Harvard Medical School
Heng Zhu
Professor, Johns Hopkins School of Medicine
Elizabeth Heller
Assistant Professor, University of Pennsylvania
Anne West
Professor of Neurobiology, Duke University
Angel Barco
CSIC Research Professor, Instituto de Neurociencias (CSIC-UMH)
Tae-Kyung Kim
77 Cheongam-ro, Nam-gu, Pohang (Nam), Gyeongbuk, South Korea, 790-784, POSTECH Life Sciences
Timothy Bredy
Professor, Queensland Brain Institute
Anne Schaefer
Associate Professor, Icahn School of Medicine at Mount Sinai
Andreas Pfenning
Assistant Professor, Carnegie Mellon University
Alon Chen
Chair, Director , Weizmann Institute of Science, Max-Planck Institute of Psychiatry
Andrew Jaffe
Lead Investigator, Lieber Institute for Brain Development
Ram Madabhushi
Assistant Professor, UT southwestern Medical Center
Yanhong Shi
Professor and Chair, Department of Neurodegenerative Diseases, Beckman Research Institute of City of Hope
Programme
SATURDAY 24TH FEBRUARY 2018 |
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14:00 – 14:45 |
Registration & Reception |
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14:00 – 14:45 |
Welcome Lunch |
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14:45 – 15:00 |
Opening Comments |
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Session 1 |
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15:00 – 15:30 |
Guo-li Ming |
EPITRANSCRIPTOMIC m6A REGULATION OF AXON REGENERATION IN THE ADULT MAMMALIAN NERVOUS SYSTEM |
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15:30 – 15:45 |
Guang-Hui Liu |
ABSENCE OF SIRT6 RESULTS IN DEVELOPMENTAL RETARDATION IN CYNOMOLGUS MONKEYS |
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15:45 – 16:15 |
Antonella Riccio |
THE SECRET LIFE OF 3’UTRS IN DEVELOPING NEURONS |
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16:15 – 16:45 |
Jesse Gray |
DISTINCT NEURONAL ACTIVITY PATTERNS INDUCE DIFFERENT GENE EXPRESSION PROGRAMS |
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16:45 – 17:15 |
Refreshments |
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17:15 – 17:45 |
Tim Bredy |
THE WHO, WHAT, WHERE, WHY AND HOW OF NEW DNA MODIFICATIONS IN THE BRAIN AND THEIR ROLE IN MEMORY |
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17:45 – 18:15 |
Andrew Jaffe |
DYNAMIC DNA METHYLATION ACROSS DEVELOPMENT, GENOTYPE AND MENTAL ILLNESS IN THE HUMAN BRAIN |
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18:15 – 18:30 |
Christina Vallianatos |
AN H3K4ME WRITER-ERASER DUO KMT2A AND KDM5C COORDINATES SOCIAL BEHAVIOR |
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18:30 – 18:45 |
Bing Yao |
DNA N6-METHYLADENINE IS DYNAMICALLY MODIFIED IN THE MOUSE BRAIN FOLLOWING ENVIRONMENTAL STRESS AND ALZHEIMER’S DISEASE |
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18:45 – 19:30 |
Chuan He |
RNA METHYLATION IN GENE EXPRESSION REGULATION |
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19:30 |
Dinner at Leisure |
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SUNDAY 25TH FEBRUARY 2018 |
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07:00 – 08:30 |
Breakfast |
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Session 2 |
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08:30 – 09:00 |
Hongjun Song |
Epitranscriptomic regulation of neurogenesis and plasticity |
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09:00 – 09:30 |
Alon Chen |
THE ROLE OF M6A-RNA METHYLATION IN STRESS RESPONSE REGULATION |
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09:30 – 09:45 |
Marija Kundakovic |
CHANGES IN NEURONAL CHROMATIN ORGANIZATION AND ANXIETY-RELATED PHENOTYPES ACROSS THE ESTROUS CYCLE |
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09:45 – 10:00 |
Felice Elefant |
RESTORING HISTONE ACETYLATION HOMEOSTASIS IN THE NEURODEGENERATIVE BRAIN RELIEVES EPIGENETIC TRANSCRIPTIONAL REPRESSION AND REINSTATES COGNITION |
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10:00 – 10:45 |
Refreshments & Group Photo |
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10:45 – 11:15 |
Rudolf Jaenisch |
EPIGENETIC REGULATION, STEM CELLS AND DISEASE RELEVANCE |
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11:15 – 11:45 |
Heng Zhu |
DNA METHYLATION-DEPENDENT KLF4 BINDING PROMOTES TRANSCRIPTION ACTIVATION AND CHROMATIN REMODELING |
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11:45 – 12:00 |
Valeria Cavalli |
GENE REPRESSION BY DNA METHYLATION PROMOTES AXON REGENERATION IN PERIPHERAL SENSORY NEURONS |
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12:00 – 12:15 |
Johannes Graeff |
REWRITE OR OVERWRITE: DECIPHERING THE NEUROEPIGENETIC MECHANISMS OF REMOTE FEAR MEMORY ATTENUATION |
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12:15 – 12:30 |
Meilin Fernandez |
DIFFERENTIAL NUCLEOSOME BINDING BY DEVELOPMENTAL AND REPROGRAMMING TRANSCRIPTION FACTORS |
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12:30 – 12:45 |
Jing Crystal Zhao |
M6A RNA METHYLATION CROSSTALK WITH HISTONE MODIFICATIONS IN NEURAL STEM CELLS |
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12:45 – 17:30 |
Lunch at Leisure & Free Time |
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Session 3 |
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17:30 – 18:00 |
Peng Jin |
DYNAMIC CHEMICAL MODIFICATIONS OF NUCLEIC ACID IN NEURODEVELOMENT AND DISEASES |
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18:00 – 18:30 |
Elizabeth A. Heller |
CHROMATIN-MEDIATED ALTERNATIVE SPLICING IN REWARD PATHOPHYSIOLOGY |
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18:30 – 19:00 |
Ram Madabhushi |
THE ROLE OF ACTIVITY-INDUCED DNA BREAKS IN NEURONAL PHYSIOLOGY, LEARNING AND MEMORY |
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19:00 – 19:15 |
Shigeki Iwase |
NEURONAL ACTIVITY-DEPENDENT TRANSCRIPTION START SITES |
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19:15 – 19:30 |
Chris Pierce |
THE SINS OF THE FATHERS: PATERNAL COCAINE ELICITS LEARNING DEFICITS IN MALE PROGENY |
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19:30 |
Dinner at Leisure |
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MONDAY 26TH FEBRUARY 2018 |
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07:00 – 08:30 |
Breakfast |
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Session 4 |
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08:30 – 09:00 |
Eric Nestler |
TRANSCRIPTIONAL AND EPIGENETIC MECHANISMS OF ADDICTION |
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09:00 – 09:30 |
Anne West |
EPIGENOME EDITING IN NEURONS WITH dCAS9 FUSION PROTEINS |
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09:30 – 09:45 |
Sika Zheng |
NEURONAL POLARIZATION IS COORDINATED BY ALTERNATIVE SPLICING REPROGRAMMING |
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09:45 – 10:00 |
Jose V. Sanchez-Mut |
PM20D1 METHYLATION QUANTITATIVE TRAIT LOCUS IS ASSOCIATED WITH ALZHEIMER’S DISEASE |
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10:00 – 10:30 |
Refreshments |
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10:30 – 11:00 |
Yanhong Shi |
M6A RNA METHYLATION REGULATES NEURAL DEVELOPMENT AND NEUROLOGICAL DISORDER |
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11:00 – 11:30 |
Tae-Kyung Kim |
ACTIVITY-REGULATED TRANSCRIPTIONAL ENHANCERS |
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11:30 – 11:45 |
Jeremy Day |
ROLE OF GADD45B IN DNA DEMETHYLATION AND COCAINE ACTION |
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11:45 – 12:00 |
Nathalie Berube |
THE CTCF CHROMATIN ORGANIZER DICTATES THE FATE OF CORTICAL GABAERGIC INTERNEURONS IN THE DEVELOPING BRAIN |
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12:00 – 17:00 |
Lunch at Leisure & Free Time |
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12:30 – 16:00 |
Snorkel Trip (signups required in advance) |
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Session 5 |
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17:00 – 17:30 |
Li-huei Tsai |
INSIGHTS INTO THE EPIGENETIC MECHANISMS OF MEMORY ENCODING, CONSOLIDATION AND RECALL |
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17:30 – 19:45 |
Poster Session |
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20:00 |
*Gala Dinner & Poster Awards* |
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TUESDAY 27TH FEBRUARY 2018 |
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07:00 – 08:30 |
Breakfast |
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Session 6 |
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08:30 – 09:00 |
Anne Brunet |
EPIGENETIC AND METABOLIC REGULATION OF NEURAL STEM CELL AGING |
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09:00 – 09:30 |
Angel Barco |
ROLE OF KAT3 PROTEINS IN NEUROPLASTICITY AND NEURONAL IDENTITY |
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09:30 – 10:00 |
Andreas Pfenning |
EPIGENOMIC DISSECTION OF REGULATORY ELEMENTS UNDERLYING THE EVOLUTION OF LEARNED VOCAL BEHAVIOR |
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10:00 – 10:30 |
Refreshments |
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10:30 – 11:00 |
Anne Schaefer |
EPIGENETIC CONTROL OF BRAIN REGION-SPECIFIC MICROGLIA CLEARANCE ACTIVITY BY PRC2 |
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11:00 – 11:45 |
Michael Greenberg |
HOW NATURE AND NURTURE CONSPIRE TO CONTROL BRAIN DEVELOPMENT AND FUNCTION |
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11:45 – 12:00 |
Closing Comments |
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Supported by
Venue & Location
Fiesta Americana Condesa
This stylish hotel features contemporary Mexican architecture, including one of the largest and most impressive thatched-roof "palapas" in the entire country. There are cultural activities, arts and crafts and sports programs to keep you constantly entertained, plus time to relax and enjoy the Mayan culture, soak up the Caribbean sunshine and revel in the international ambiance that settles in after the sun goes down.
Throughout your stay delegates will enjoy a full meal plan, inclusive of beverages. Take your pick from the aromatic Asian delights at Kaumbu, traditional fare at El Mexicano, delicious international cuisine at Kalmia Buffet or perhaps sample the sumptuous Italian dishes at Rosato. There are also several other dining opportunities such as the Cevichería, Pizzeria, Sushi Corner, pool and lounge bar areas. The Gala Night with either a Mayan or Caribbean theme takes place on the third evening of the conference with a mouth-watering feast of local cuisine, an open bar and amazing local entertainment. We welcome all delegates and their accompanying persons to the Gala Night – a truly fun filled night not to be missed!
Hotel Facilities
- Lagoon Pool
- Extensive Health Club and Spa
- Complimentary Wi-Fi in guest rooms and throughout hotel and conference areas
The Fiesta Americana Condesa, Cancun is the 2015 Winner of the Trip Advisor Certificate of Excellence and also received the Travellers Choice Award in 2014.
The remains of ancient Mayan cities are scattered throughout the Yucatan Peninsula and no trip to Cancun would be complete without a visit to these majestic temples and pyramids set amongst lush tropical vegetation. We will be working very closely with a reputable tour company who will be organising trips to Tulum, Chichen Itza, Coba and Xcaret to name a few, some of which may require a full day. Full day excursions will be arranged pre or post conference and may be on an individual or group booking so we would recommend booking extra nights to extend your stay as early as possible to avoid disappointment should these excursions be of interest to you and/or your party. For further information please contact us.
General Information
Venue Rating
★ ★ ★ ★ ★
Currency
US Dollar (USD)
Address
Fiesta Americana Condesa, Blvd.Kukulkán km 16.5 Zona Hotelera, Cancun, 77500 Mexico
Nearest Airport
Cancun International Airport
Location
Cancun is a delightful combination of natural beauty, islands, ecological reserves and white sandy beaches. However, besides sun, sand and sea, this destination also offers an infinite variety of underwater activities to choose from: the diving, snorkelling and fishing here are outstanding and you will find an undersea world packed with tropical fish that live on the second largest barrier reef in the world. Sports enthusiasts might choose one of the many eco-tourism activities, such as cycling or hiking through the tropical forest or kayaking through mangroves, or something a little more adventuresome, like zip lining through the treetops.
Apart from the more well-known ancient Mayan archealogical sites such as Tulum, Cobá and Chichén Itzá you may like to visit the Aktun Chen caverns, voted one of the Top 10 underwater walks by National Geographic described as a truly magical experience.
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