Synopsis

Mitochondria act at the interface of numerous processes critical for cellular function and organismal health. Long recognized as the powerhouses of the cell, mitochondria are emerging as hubs for cellular metabolism, redox balance, signalling, gene expression, detoxification, and ion homeostasis. Mitochondrial maintenance is critical for proper development and function of cells and tissues, and mitochondrial dysfunction underlies numerous disease processes ranging from severe childhood mitochondrial disorders, to heart disease, neurodegenerative disorders, cancer, and aging itself. This conference will bring together scientists and clinicians with expertise in a breadth of mitochondrial biology to explore topics at the interface of basic and translational biology. Mitochondrial basic mechanisms of organelle regulation, mitochondrial mechanisms of disease, cutting edge technologies, and interventional strategies will be emphasized in interactive scientific sessions.

Joint Session with 4th Interventions in Aging Conference

We are holding a joint session between the 2^nd Mitochondria conference and the 4^th Interventions in Aging conference. The session will take place on the 22^nd July. Mitochondria play a key role in the aging process, with mitochondrial density and activity declining in specific tissues, associated with loss of respiratory and metabolic functions. Discovering how to prevent this age-related decline is therefore an important goal of research into aging.

Registration for the Mitochondria conference includes access to the joint session, as well as a group lunch and dinner on the 22^nd July. If you would like to extend your stay to arrive on the 21^st July ahead of the joint session, this would be at a cost of €158 and includes bed and breakfast only. This can be added via your Fusion account. Dinner on the 21^st July would be at leisure and at your own expense.

Please note that registration for the 2^nd Mitochondria conference does not include registration for the 4^th Interventions in Aging conference. If you are interested in registering for both meetings, we can offer a 10% discount off your second registration, please contact Chloe Trundle for further information.

Student Offer

Take advantage of this fantastic opportunity for students! Fully paying academics can bring a student for only €830. Unfortunately, Postdocs are not eligible. Both registration packages include; accommodation for the 22, 23, 24 July 2021 (on a shared basis for students) and a food and beverage package for the conference period. Once registered, please contact Chloe Trundle to obtain a special registration link for your student. 

Confirmed Speakers

Rozalyn Anderson (University of Wisconsin, Madison)
Facundo Batista (Harvard University)
SHAPING ANTIBODY RESPONSES: AUTOPHAGY, MITOCHONDRIA, METABOLISM AND MORE…
John Blenis (Weill Cornell Medicine)
Cornelis Calkhoven (ERIBA)
Nav Chandel (Northwestern University)
MITOCHONDRIA AS SIGNALING ORGANELLES
Ayelet Erez (Weizmann Institute of Science)
TARGETING AMINO-ACID METABOLISM FOR CANCER DIAGNOSIS AND THERAPY
Sarah-Maria Fendt (VIB - KU Leuven Center for Cancer Biology)
Simon Johnson (University of Washington)
MECHANISMS UNDERPINNING THE BENEFITS OF mTOR INHIBITION IN LEIGH SYNDROME
Franck Kalume (University of Washington)
Alicia Kowaltowski (University of Sao Paulo)
DIETARY INTERVENTIONS, MITOCHONDRIA, AND METABOLIC REGULATION
Samantha Lewis (UC Berkeley)
REGULATION OF MITOCHONDRIAL GENOME REPLICATION IN ANIMAL CELLS
Maria Mittelbrun (Universidad Autónoma de Madrid)
Paula Moreira (University of Coimbra)
Erika Pearce (Max Planck Institute of Immunobiology and Epigenetics)
Albert Quintana (Universitat Autònoma de Barcelona)
UNTANGLING CELL-TYPE SPECIFIC NEURODEGENERATION MECHANISMS IN MOUSE MODELS OF MITOCHONDRIAL DISEASE
Michael Ristow (ETH Zurich)
Birgit Schilling (Buck Institute)
Eric Verdin (Buck Institute)
Karen Vousden (Francis Crick Institute)
THE ROLE OF MITOCHONDRIAL ROS IN CANCER PROGRESSION

Target Audience

• Basic scientists studying mechanisms of mitochondrial and cell biology
• Clinicians and translational biologists interested in mitochondrial disease
• Neuroscientists studying mitochondrial function and role of mitochondria in neurodegenerative disease
• Scientists studying processes where mitochondria are important (metabolism, aging, cancer, heart function, etc.)

Educational Need

Mitochondria function at the intersection of many important areas of biology and biomedicine, but there are limited opportunities for people studying different areas of biology where mitochondria are important (aging, neurodegenerative disease, inherited disorders, mitochondria disease, heart disease, myopathies and muscular dystrophies, evolutionary biology, obesity, diabetes, kidney disease, etc.) to come together at one meeting.  The primary outcome we hope to stimulate is interaction and cross fertilization of ideas between these diverse scientists leading to new collaborations and synergistic advances.