Programme
Although the programme has not yet been released, we are able to confirm that the conference should begin no earlier than 13:00 with opening comments on 07 May 2025. The conference will conclude no later than 12:30 on 10 May 2025.
07 May 2025 - 10 May 2025
Chania, Crete
Chairs
Alzheimer’s disease (AD) is the most common age-dependent neurodegenerative disease, affecting nearly 1 in 9 people over 65 in the world. While a great progress in translational and discovery research is excitingly being made, there still lack effective therapies for AD and related neurodegenerative diseases. This planned conference intends to bring together leading scientists and clinicians from all over the world to present their unpublished observations or findings to attendees, and to share their vision or prospects on translational or discovery research. We expect that some presenters, either by talks or posters, will discuss our current state of knowledge in disease mechanisms, novel targets, new genetic association or pathways, approaches for identifying new therapeutic targets, and biomarkers for diagnosis or treatment readouts. We will also invite speakers who are conducting later stages of drug discoveries to share clinical trial results.
David Bennett (Rush University)
Mathew Blurton-Jones (University of California, Irvine)
HARNESSING STEM CELL DERIVED MICROGLIA FOR BRAIN-WIDE DELIVERY OF THERAPEUTIC PROTEINS
Guojun Bu (Hong Kong University of Science and Technology)
PATHOBIOLOGY AND THERAPEUTIC STRATEGIES AGAINST APOE IN ALZHEIMER’S DISEASE
Karen Duff (University College London)
TAUOPATHY MECHANISMS IN FTD AND AD
René Frank (University of Leeds)
Li Gan (Weill Cornell Medicine)
NEUROIMMUNE INTERACTIONS IN NEURODEGENERATIVE DISEASES
Christian Haass (Ludwig-Maximilians University Munich)
MODULATION OF TREM2 ACTIVITY BY AN AGONISTIC ANTIBODY
Michael Heneka (University of Luxembourg)
Joachim Herz (UT Southwestern Medical Center)
David Holtzman (Washington University in St. Louis)
ROLE OF APOE AND THE INNATE AND ADAPTIVE IMMUNE RESPONSE IN THE PRESENCE OF ALZHEIMER’S-LIKE PATHOLOGIES
Yadong Huang (Gladstone Institutes, University of California San Francisco)
NEURONAL APOE4 TOXICITY IN ALZHEIMER'S DISEASE
Celeste Karch (Washington University in St. Louis)
Jonathan Kipnis (Washington University in St. Louis)
IMMUNE CELL-BASED THERAPEUTIC APPROACHES FOR NEURODEGENERATIVE DISEASES
Yueming Li (Memorial Sloan Kettering Cancer Center)
Richard Mayeux (Columbia University)
THE PATHOGENIC ROLES OF APOE IN ALZHEIMER’S DISEASE AND POTENTIAL THERAPEUTIC STRATEGIES
Inhee Mook-Jung (Seoul National University)
GUT-VAGUS NERVE-BRAIN AXIS IN ALZHEIMER'S DISEASE PATHOGENESIS
Priyanka Narayan (NIH)
Pannos Roussos (Icahn School of Medicine at Mount Sinai)
Michal Schwartz (Weizmann Institute of Science)
Sam Sisodia (University of Chicago)
Gopal Thinakaran (University of South Florida)
BIN1 RISK IN ALZHEIMER'S DISEASE: UNPACKING THE COMPLEX MECHANISMS, ONE BIN AT A TIME
Taisuke Tomita (University of Tokyo)
TARGETING NEUROINFLAMMATORY RESPONSE FOR ACCELERATED AMYLOID CLEARANCE IN ALZHEIMER DISEASE
Robert Vassar (Northwestern University)
Matheus Victor (Icahn School of Medicine at Mount Sinai)
Michael Ward (NIH)
Tracy Young-Pearse (Harvard University)
Hui Zheng (Baylor College of Medicine)
GLIAL CELL-SURFACE PROTEINS IN AD
• The latest on AD genetics
• Peripheral and central immune response
• Multiomic dissection of AD
• Vulnerability and resilience
• Lipid and metabolic abnormalities in AD pathogenesis
• Novel therapeutic targets
• New Biomarkers
• AI or machine learning-based drug discovery
• Insights from molecular structures
• Brain imaging of AD brains
The significance of having this conference is to provide a unique forum for the research community focusing on translational studies geared towards therapies in AD and related neurodegenerative diseases to come together to discuss the latest advances and the future challenges in the field.
The conference is essentially open to various levels of investigators including senior, mid career and early career investigators, either in academic or industrial or clinical institutes. There will be ample opportunities for attendee to have close interactions networking and freely scientific discussions. We anticipate international representation from the US, Europe, Canada, Japan, Korea, China, and others.
Junior investigators such as graduate students or postdoctoral fellows as well as physician scientists are expected to gain knowledge on the most current therapeutic strategies in AD and the related field. The conference will also be of interest to clinical practioners seeking updates on what developments are underway in the therapeutic pipeline for AD and the scientific basis of this research pathway.
07 May 2025 - 10 May 2025
Chania, Crete
Chairs
David Bennett
Rush University
Mathew Blurton-Jones
University of California, Irvine
Guojun Bu
Hong Kong University of Science and Technology
Karen Duff
University College London
René Frank
University of Leeds
Li Gan
Weill Cornell Medicine
Christian Haass
Ludwig-Maximilians University Munich
Michael Heneka
University of Luxembourg
Joachim Herz
UT Southwestern Medical Center
David Holtzman
Washington University in St. Louis
Yadong Huang
Gladstone Institutes / University of California San Francisco
Celeste Karch
Washington University in St. Louis
Jonathan Kipnis
Washington University
Yueming Li
Memorial Sloan Kettering Cancer Center
Richard Mayeux
Columbia University
Inhee Mook-Jung
Seoul National University
Priyanka Narayan
NIH
Panos Roussos
Icahn School of Medicine at Mount Sinai
Michal Schwartz
Weizmann Institute of Science
Sam Sisodia
University of Chicago
Gopal Thinakaran
University of South Florida
Taisuke Tomita
University of Tokyo
Robert Vassar
Northwestern University
Matheus Victor
Icahn School of Medicine at Mount Sinai
Michael Ward
NIH
Tracy Young-Pearse
Harvard University
Hui Zheng
Baylor College of Medicine
07 May 2025 - 10 May 2025
Chania, Crete
Chairs
Although the programme has not yet been released, we are able to confirm that the conference should begin no earlier than 13:00 with opening comments on 07 May 2025. The conference will conclude no later than 12:30 on 10 May 2025.
07 May 2025 - 10 May 2025
Chania, Crete
Chairs
Ticket Type | Early Bird | Full Price |
---|---|---|
Single
Choose this option if you will be attending the conference alone, or if you will bring accompanying guests that will not attend the meeting.
|
€2181 | €2277 |
Shared
Choose this option if you wish to share with a colleague who is also attending the conference, or if you wish to be paired with another attendee of the same sex.
|
€1923 | €2019 |
Student
Choose this option if you are a student. Please note all students will be paired with another attendee of the same sex if a room sharer is not specified. If you wish to have your own room, please register under the Single option.
|
€1006 | €1006 |
Adult
€581
Child
€0
Adult
€249
Child
€0
All registration fees include 3 nights accommodation and meals during the conference period. Exact inclusions are detailed below.
Our registration fees are inclusive of the following at Avra Imperial Hotel during the conference period only:
- Conference registration.
- 3 nights fixed accommodation (07, 08, 09 May 2025) on a single or shared basis in a Deluxe Room with Garden View.
- Buffet breakfast at Basilico restaurant on 07, 08, 09 and 10 May 2025.
- Buffet lunch at Basilico restaurant with free flow soft drinks and mineral water on 07, 08, 09 and 10 May 2025.
- Buffet dinner at Basilico restaurant with free flow wine, beer, soft drinks and mineral water on 07 and 08 May 2025.
- Gala buffet dinner at Blue Dong restaurant with free flow wine, beer, soft drinks and mineral water on 09 May 2025.
- Daily coffee breaks.
- Complimentary WIFI throughout the hotel.
Our accompanying adult fees are inclusive of the following at Avra Imperial Hotel during the conference period only:
- 3 nights’ fixed accommodation (07, 08, 09 May 2025) on a shared basis with a conference participant in a Deluxe Room with Garden View.
- Buffet breakfast at Basilico restaurant on 07, 08, 09 and 10 May 2025.
- Buffet lunch at Basilico restaurant with free flow soft drinks and mineral water on 07, 08, 09 and 10 May 2025.
- Buffet dinner at Basilico restaurant with free flow wine, beer, soft drinks and mineral water on 07 and 08 May 2025.
- Buffet gala dinner at Blue Dong restaurant with free flow wine, beer, soft drinks and mineral water on 09 May 2025.
- Complimentary WIFI throughout the hotel.
Important Note: Accompanying guests are not permitted access to the conference.
Our accompanying child fees are inclusive of the following at Avra Imperial Hotel during the conference period only:
- 3 nights’ fixed accommodation (07, 08, 09 May 2025) on a shared basis with the parent/s in a Deluxe Room with Garden View, max 1 child per room.
- Buffet breakfast at Basilico restaurant on 07, 08, 09 and 10 May 2025.
- Buffet lunch at Basilico restaurant on 07, 08, 09 and 10 May 2025.
- Buffet dinner at Basilico restaurant on 07 and 08 May 2025.
- Gala buffet dinner at Blue Dong restaurant on 09 May 2025.
- Drinks for children are not included and will be charged on consumption at the time of dining.
- Complimentary WIFI throughout the hotel.
Important Note: Accompanying children up to and including the age of 12 years stay free of charge with an adult. Children aged 13 years and older are classified as an adult at Avra Imperial Hotel. The maximum occupancy is 2 adults and 1 child per room in a Deluxe Room with Garden View. If you wish to add more than 1 child to your booking, you will need to pay a supplement for a Family Room which has a maximum occupancy of 2 adults and 2 children. The supplement is €58 per night assuming 2 adults occupy the room, or €79 per night assuming 1 adult occupies the room. Please contact us if you wish to book a Family Room so we can check availability. Please kindly ensure your child / children are supervised at all times during conference and related events. Childcare services are available at the hotel, please contact Rosie for further information.
Our extra night fees are inclusive of the following at Avra Imperial Hotel during the conference period only:
- 1 night’s accommodation for 1 person in a Deluxe Room with Garden View.
- Buffet breakfast at Basilico restaurant.
- Buffet lunch at Basilico restaurant with free flow soft drinks and mineral water.
- Buffet dinner at Basilico restaurant with free flow wine, beer, soft drinks and mineral water.
- Complimentary WIFI throughout the hotel.
Important Note: The extra night price is only applicable 3 nights pre/post the conference dates. If you wish to extend your stay further, this is possible to book via Fusion, but please contact Rosie for assistance and prices. Accompanying children up to and including the age of 12 years stay free of charge with an adult. Drinks for children are not included and will be charged on consumption at the time of dining. Children aged 13 years and older are classified as an adult at Avra Imperial Hotel. The maximum occupancy is 2 adults and 1 child per room in a Deluxe Room with Garden View. If you wish to add more than 1 child to your booking, you will need to pay a supplement for a Family Room which has a maximum occupancy of 2 adults and 2 children. The supplement is €58 per night assuming 2 adults occupy the room, or €79 per night assuming 1 adult occupies the room per night, per room. Please contact us if you wish to book a Family Room so we can check availability.
Prices and hotel availability are subject to change without notice.
07 May 2025 - 10 May 2025
Chania, Crete
Chairs
07 May 2025 - 10 May 2025
Chania, Crete
Chairs
07 May 2025 - 10 May 2025
Chania, Crete
Chairs
The Aging and Associated Diseases Research Network LinkedIn group is an excellent platform to connect with fellow attendees and likeminded researchers prior to the conference. The group is open to all and is intended as a networking forum for past, present and future participants of Fusion Conferences as well as those interested in the related topics.To join, please follow the link below.
07 May 2025 - 10 May 2025
Chania, Crete
Chairs
The Avra Imperial Hotel is situated on the picturesque bay of Kolymbari, 23km west of Chania, in Crete. Located next to the beautiful beach of Kolymbari, awarded with the EU Blue Flag, set amongst 65,000m² of fragrant lush gardens and surrounded by crystal clear turquoise waters of the Cretan sea with stunning views over the semi-mountainous peninsula, this makes for a wonderful setting for this conference.
With top class facilities including impressive swimming pools, five excellent restaurants and four vibrant bars, sports & leisure facilities, crèche & children’s club, shops, plus a rejuvenating and uniquely designed spa, there is plenty to occupy your free time whether you choose to relax and stay within the hotel or decide to venture further afield and see what Crete has to offer.
The themed Gala Night takes place on the penultimate evening of the conference with a mouth-watering feast of local cuisine, a bar and amazing local entertainment. We welcome all delegates and their accompanying persons to the Gala Night – a truly fun filled night not to be missed!
Venue Rating
Currency
Euro (EUR)
Address
Kolymbari 73006 Chania Crete Greece.
Nearest Airport
Chania International Airport
Hotel Facilities
Hotel facilities include:
Situated 23km west of Chania, Avra Imperial Hotel is positioned in the village of Kolymbari (or Kolimbari, Kolymvari), a true Cretan seaside village, surrounded by olive goves, located on the corner formed between the northern coastline of western Crete and the Rodopos peninsula stretching towards north. The waterfront and the jetty of the new harbor, that encloses the oldest small harbor with fishing boats, is ideal for a stroll in the afternoon, overlooking the blue of the sea, on one side, and on the other, the hills and the mountains of Rodopos peninsula, rising behind the house roofs.
07 May 2025 - 10 May 2025
Chania, Crete
Chairs
There are two main airports in Crete:
Chania International Airport is located 39km from the Avra Imperial Chania, approximately 40 minutes journey time.
Heraklion International Airport is located 162.5 km from the hotel and the journey time is approximately 2hrs 15min.
There are frequent daily flights to and from the UK and Europe to both airports. If travelling from the USA, most flights are scheduled via Athens with an inter-connecting flight on to Chania International / Heraklion international.
The taxi rank is located outside the terminal building, however, during busy periods, it is recommended you pre-book your airport transfer to avoid long waiting times.
There are various suppliers that offer pre-booked airport transfer to and from both Chania and Heraklion airports. Please find details of a few that we are aware of below. However, should you require further information, or would like to make a booking, please contact the company directly. Pre-booked transportation prices vary from €57 (up to 4 people) from Chania International Airport to the Avra Imperial Hotel and €180 (up to 4 people) from Heraklion Airport to the Avra Imperial Hotel. Rates are based on a single journey; discounts may be available for a pre-booked return trip:
Crete Lux Travel
Contact Email: info@creteluxtravel.com
Website: https://creteluxtravel.com/
Taxi Limo Chania
Contact Email: info@taxilimochania.gr
Website: https://taxilimochania.gr
Chania Taxi & Van
Contact Email: info@taxivan-chania.gr
Website: http://www.taxivan-chania.gr/
Edem Travel
Contact Email: info@edemtravel.gr
Website: https://www.edemtravel.gr/
Crete Taxi Van
Contact Email: info@cretetaxivan.gr
Website: https://www.cretetaxivan.gr
**Any bookings and transactions made with the above suppliers are the sole responsibility of the individual.
07 May 2025 - 10 May 2025
Chania, Crete
Chairs
Chania is one of the prettiest towns on the island of Crete, with its cobbled streets filled with shops selling clothes, ceramics, and local artworks, and restaurants and cafes overlooking the Venetian harbour, but if you fancy venturing further afield, we have listed a few suggestions below.
The Old Port
Dating from the 14th century, the old harbour is ringed by a promenade lined with seafood eateries and cafés. As you wander to the east of the old harbour, you'll pass by the small mosque, erected by the Ottoman Turks after they took Chania in 1645. Today it serves as a small art gallery. Beyond the mosque stand the arsenals, where the Venetians repaired their galleys. There is also a yachting marina.
Walk the Seawall to the Lighthouse
One of the best views of the old port and Chania's old town can be found by taking a stroll along the Venetian seawall to the 19th-century lighthouse. The walk takes about 15 minutes one way, at a leisurely pace. This walk will also take you by some of the main sights in the old port, including the Yiali Tzami mosque and the Venetian arsenals. Although the lighthouse is not open to visitors, you can still climb the set of stairs to the first level.
Maritime Museum of Crete
The museum traces Crete's centuries-old relationship with the sea, from the Minoans, through the Byzantine, Venetian, and Turkish periods, to arrive at the German invasion of the island during WWII. Spread over two floors, the collection includes video presentations, amazing models of ships, paintings, photos, and nautical equipment
Archaeological Museum of Chania
Chania's history dates back millennia to somewhere around 2200 BC, when the Minoans founded the ancient city-state of Kydonia on this same spot. You will be able to view archeological finds from western Crete dating from Neolithic times through to the Roman era, with a vast array of ceramics, painted burial urns, gold jewellery, and clay tablets with inscriptions to name a few.
Botanic Park & Gardens of Crete
Crete is well known for growing olives and grapes, but also farms tropical fruits, such as avocados and bananas. In this carefully tended park, at the foot of the White Mountains, you can follow a two-kilometer path that will take you through a garden planted with exotic flowers and fruit trees from all over the world. Sit in a shady spot to take in the wonderful aroma of the fragrant herbs or visit the café-restaurant where they serve Cretan dishes prepared with the park’s own seasonal produce.
The Monasteries of Akrotiri Peninsula
The rocky peninsula of Akrotiri, 10 kilometres east of Chania, is home to three monasteries; Agia Triada, Gouverneto and Katholiko, each one set in beautiful surroundings with unique characteristics.
Day Trip to Hike the Samaria Gorge
For the adventurers among you, take a day trip to hike the Samaria Gorge, the longest of Crete’s deep cut gorges at 18 kilometres. You can do the hike independently or as part of an organised trip, which is highly recommended as the hike is quite complex and challenging. This is a one-way hike, so you need to consider transport back to your starting point before embarking on this activity. Entrance to the gorge is at the village of Omalós, 42 kilometres south of Chania. The hike is almost all downhill, with the gorge opening out to the sea at the village of Ayía Rouméli, with a black-sand beach where you can swim at the end of your hike to cool you down.
07 May 2025 - 10 May 2025
Chania, Crete
Chairs
07 May 2025 - 10 May 2025
Chania, Crete
Chairs
We have several oral opportunities available at this meeting. To be considered for a talk, please register for the conference and upload your abstract when prompted to do so. You will be able to monitor the status of your abstract through your Fusion account and you will also receive an email if you are successful or unsuccessful.
Please use the abstract template provided (see below) and ensure your abstract is no longer than one page in length.
If you are accepted for a talk, we recommend you check our website regularly as the conference approaches. Regular programme updates will be released under the ‘Programme’ tab on the conference website.
Your Presentation
On the day of your presentation please make yourself known to our AV technician who will be present in the conference room. We advise running through your presentation at least 30minutes prior to your session commencing to ensure your slides and any videos or animations appear as expected. We prefer our speakers to run their presentation from the master PC or Mac, however, if you prefer to use your own laptop then please notify us prior to the session. A HDMI or VGA cable is usually available on the podium.
Our AV technician will apply your microphone and provide a combined slide advancer and laser pointer.
We ask all speakers to adhere to their time slots and respect their fellow presenters. A visual traffic light aide will be available to warn presenters as their time decreases.
Please make sure your presentation adheres to the following guidelines.
Aspect Ratio: On Screen Show (16:9)
File Type: Please save your presentation in PPT, PPTS or Keynote format
07 May 2025 - 10 May 2025
Chania, Crete
Chairs
We have several poster opportunities available at this meeting. To be considered for a poster presentation, please register for the conference and upload your abstract when prompted to do so. You will be able to monitor the status of your abstract through your Fusion account and you will also receive an email if you are successful or unsuccessful.
Please use the abstract template provided (see below) and ensure your abstract is no longer than one page in length.
Our poster boards can accommodate a maximum poster size of A0 (1189H x 841W mm), portrait in orientation. Posters exceeding this size may not fit on the poster boards provided and therefore we may be unable to display your poster, so please kindly keep to these measurements.
Displaying & Presenting Your Poster
Please bring your poster to registration and hand this to a member of the Fusion team. They will advise of your poster number and display your poster for you.
Your poster will remain on display for the duration of the conference, allowing presenters to take advantage of the refreshment breaks and free time for valuable networking opportunities, in addition to the official poster session.
Please check the programme and note the date and time of the poster session(s). Your poster will be judged during the poster session and prizes will be awarded at the Gala Dinner.
Posters will be taken down by the Fusion team and will be ready for collection at the Fusion desk on the final day of the conference.
Download Abstract Template07 May 2025 - 10 May 2025
Chania, Crete
Chairs
01 Jun 2018, 04 Jun 2018
Melia Nassau Beach All Inclusive, Nassau, Bahamas
Alzheimer’s disease (AD) is the most common age-dependent neurodegenerative disease, which affects over 5 million people in the US and over 35 million people worldwide. Currently, only four drugs are approved for alleviating symptoms in AD p...
More Information07 May 2025, 10 May 2025
#TargetAD25
Avra Imperial, Chania, Crete
Alzheimer’s disease (AD) is the most common age-dependent neurodegenerative disease, affecting nearly 1 in 9 people over 65 in the world. While a great progress in translational and discovery research is excitingly being made, there st...
More InformationIf you are interested in this meeting but not yet ready to register, you can sign up for updates here and our team will keep you updated regarding deadline reminders and grant opportunities relating to this meeting only.
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