As the impacts of COVID-19 continue, we have taken the decision to go virtual with the 4th Interventions in Aging conference. The meeting will now have a three day program starting on 19th October and will conclude 21st October 2021.

Our virtual website will launch in May 2021. If you are interested in joining us, please register your interest here. Our team will notify you when registration opens and keep you updated with forthcoming deadlines and grant opportunities.

A plethora of genetic, dietary and pharmacological interventions can extend healthy lifespan in laboratory animals, and can delay or ameliorate diverse aging-related diseases. Mechanisms of aging are conserved in evolution, and discoveries made in animals are informing our understanding of human aging. This raises the intriguing possibility of performing preventative medicine against chronic and age-related diseases, by targeting their main risk factor, namely aging. Important current challenges in the field are (1) to understand the downstream pathways by which longevity interventions can combat age-related loss of function and pathology, (2) to evaluate the impact of regenerative interventions and cellular reprogramming on age-related diseases, and (3) to translate the findings into the extension of human health span.  

This fourth meeting will continue to explore these topics, with particular emphasis on what we can learn from variation in the rate of ageing in the natural world, mitochondria, cellular senescence, biomarkers and epidemiology, immune aging and reprogramming and rejuvenation strategies.

Key Sessions

• Mitochondrial quality control and aging / joint session with 2nd Mitochondria Conference
• Ultra long lives and immortality
• Autophagy and proteostasis
• Regenerative interventions and cellular reprogramming
• Human ageing: biomarkers  and cell senescence
• Microbiome and aging

Joint Sesession with 2nd Mitochondria Conference

We are holding a joint session between the 4th Interventions in Aging Conference and the 2nd Mitochondria Conference. The session will take place on the 22nd July. Mitochondria play a key role in the aging process, with mitochondrial density and activity declining in specific tissues, associated with loss of respiratory and metabolic functions. Discovering how to prevent this age-related decline is therefore an important goal of research into aging.

Registration for the Aging conference includes access to the joint session and a group lunch on the 22nd July. If you would be interested in joining an additional group dinner on the 22nd July, this would be at a cost of €42 and you would need to sign up in advance by contacting Laura Trundle. Furthermore, if you would like to extend your stay to include the night of the 22nd July, this would be at a cost of €158 for bed and breakfast only, and you will need to add this via your Fusion account.

Please note that registration for the 4th Interventions in Aging conference does not include registration for the 2nd Mitochondria conference. If you are interested in registering for both meetings, we can offer a 10% discount off your second registration, please contact Chloe Trundle for further information.

Student Offer

Take advantage of this fantastic opportunity for students! Fully paying academics can bring a student for only €830. Unfortunately, postdocs are not eligible. Both registration packages include; accommodation for the 19, 20, 21 July 2021 (on a shared basis for students) and a food and beverage package for the conference period. Once registered, please contact Laura Trundle to obtain a special registration link for your student. 

Confirmed Plenary Speakers

Yves Barral (ETH Zurich)
Ivan Dikic (Goethe University)
Nils Goran Larsson (Karolinska Institutet)
Joan Mannick (Life Biosciences)
Masayo Takahashi (Vision Care Inc.)
RETINAL CELL THERAPY USING iPS CELLS

Confirmed Invited Speakers

Joris Deelen (Max Planck Institute for Biology of Ageing, Cologne)
DECIPHERING THE MOLECULAR FUNCTION OF GENETIC VARIANTS INVOLVED IN HUMAN LONGEVITY
Filipe Cabreiro (University College London)
IMPROVING HEALTHY AGEING THROUGH DRUG-MICROBIOTA-HOST SYNERGIES
Robin Franklin (University of Cambridge)
MYELIN REGNERATION IN THE CNS: REVERSING THE RAVAGES OF TIME
Judith Frydman (Stanford University)
Martin Graef (Max Planck Institute for Biology of Ageing, Cologne)
Cole Haynes (University of Massachusetts Medical School)
Brian Kennedy (National University of Singapore)
INCREASING THE INTERVENTION POOL TO EXTEND HEALTHSPAN
Trevor Lawley (Wellcome Sanger Institute)
HUMAN MICROBIOMES OVER LIFE COURSE
Morgan Levine (Yale School of Medicine)
Joana Neves (University of Lisbon)
Tom Reh (University of Washington)
John Sedivy (Brown University)
Andrei Seluanov (University of Rochester)
LONGEVITY MECHANISM IN LONG LIVED MAMMALS
Thaddeus Stappenbeck (Cleveland Clinic Lerner Research Institute)
HUMAN VARIATION IN INTESTINAL EPITHELIAL STEM CELLS IN RESPONSE TO INFLAMMATORY CONDITIONS SUCH AS AGING, IBD AND OBESITY
Claire J. Steves (King's College London)
Dario Riccardo Valenzano (Max Planck Institute for Biology of Ageing, Cologne)
MICROBIOTA-HOST INTERACTIONS DURING AGING
Pedro Sousa Victor (University of Lisbon)

Target Audience

• Basic scientists in the field of aging research using animal models.
• Human researchers interested in biomarkers of aging
• Clinical trials specialists in aging and associated diseases.
• Scientists and other professionals developing aging interventions.
• Investors looking to enter this new space
• Educated public

Educational Need

The aging field encompasses a wide range of biology, involving many model organisms and, with respect to mammals, the involvement of many tissues. In addition, translational strategies to modify the rate of aging range from lifestyle change to drugs and, more recently stem cell-based therapeutics. As such, there is an abiding need to bring together scientists across diverse fields with the purpose of providing a clear overview of the state of basic research in aging and the development of translational strategies. The goal is to create cross-fertilization between scientists in different areas, accelerating the development of interventions that extend human health span.

Although the programme has not yet been released, we are able to confirm that the conference should begin no earlier than 14:00 with opening comments on 19th July 2021. The conference will conclude no later than 12:30 on 22nd July 2021.