Past Conference

3rd Cell Death, Cell Stress & Metabolism Conference

Impact on Inflammation, Immunity & Disease                                                                                          #CDCSM22

Date

07 May - 10 May 2022

Location

Cancun, Mexico

Early Bird - Expired  •  Talk Submission - Expired  •  Poster Submission - Expired  •  Registration & Payment Deadline - Expired

Synopsis

The interplay between cell death, cell stress and metabolism is crucial for sensing danger posed by pathogens but also in the response to pathogen-independent tissue damage. These processes are almost invariably associated with inflammation which can result in several different outcomes: (i) induction of an effective immune response to the infective agent; (ii) increased tissue damage; and (iii) and the immunological response that is mounted to response to them. At this conference we will discuss the basic biological principles that govern cell death, cell stress and metabolism. We will also cover how cellular stress and alterations in metabolism influence the cellular death programs such as apoptosis, necroptosis, ferroptosis and others.  Importantly, this conference aims to become the go-to forum at which the most current and up-to-date therapeutic avenues in the fields of cell death, cell stress and metabolism will be presented and discussed. 

Key Sessions

  • Tumor Metabolism and Cell Intrinsic Pathways
  • Cancer Biology and the Tumor Microenvironment
  • Translational Control Mechanisms and Oncogenesis
  • Cell Death and Inflammation Signaling
  • Necroptosis, Ferroptosis and Beyond

Student Offer

Take advantage of this fantastic opportunity for students! Fully paying academics can bring a student for only $765. Unfortunately, Postdocs are not eligible. Both registration packages include; accommodation for the 7, 8, 9 May 2022 (on a shared basis for students) and a 24hour all-inclusive food and beverage package for the conference period. Once registered, please contact Jack Peters to obtain a special registration link for your student. 

Confirmed Invited Speakers

Michael Bergmann (Medical University of Vienna)
Mathieu Bertrand (VIB Center for Inflammation Research / Ghent university)
Navdeep Chandel (Northwestern University)
MITOCHONDRIA AS SIGNALING ORGANELLES
Mads Daugaard (University of British Columbia)
Gina DeNicola (Moffitt Cancer Center)
NRF2 AND CYSTEINE METABOLISM
Scott Dixon (Stanford University)
A PALMITOYLATION-DEPENDENT NON-APOPTOTIC CELL DEATH MECHANISM
Douglas Green (St. Jude Children's Research Hospital)
PERSISTER ACT: NEAR DEATH EXPERIENCES IN CANCER CELLS
Atan Gross (Weizmann Institute of Science)
Peter Kreuzaler (The Francis Crick Institute / University of Cologne)
Gianmaria Liccardi (University of Cologne)
MITOTIC CELL DEATH: A CYCLE FULL OF CINS AND SURPRISES
Andreas Linkermann (UKD Dresden)
THE MALE VS THE FEMALE: FAILURE TO PROTECT FROM FERROPTOSIS EXPLAINS MALE HYPERSENSITIVITY TO ACUTE KIDNEY TUBULAR NECROSIS
Scott Lowe (MSKCC)
Anne von Mässenhausen (Nephrologie Dresden)
DEXAMETHASONE SENSITIZES TO FERROPTOSIS BY GLUCOCORTICOID RECEPTOR-INDUCED DIPEPTIDASE-1 EXPRESSION AND GLUTATHIONE DEPLETION
Claudio Mauro (University of Birmingham)
UNDERSTANDING THE LONG-LASTING EFFECTS OF SATURATED FATTY ACIDS ON THE ADAPTIVE IMMUNE RESPONSE
Raphaël Rodriguez (Institut Curie)
Davide Ruggero (University of California, San Francisco)
Luca Scorrano (University of Padua)
KEEPING MITOCHONDRIA IN SHAPE: A MATTER OF CELL LIFE AND DEATH
Tom Vanden Berghe (University of Antwerp)
FERROPTOSIS TARGETING, LIFESAVING @ INTENSIVE CARE UNITS?

Target Audience

From basic researchers all the way to people in the biotech and pharma industries who are interested in cell death, cell stress, metabolism, inflammation, immunity and their impact on disease, would like to be on top of the newest development in this interconnected field and want to form part of a meeting which is specifically geared towards providing a platform for the presentation and discussion of up-to-date fundamental, preclinical and translational research.

Confirmed Speakers

Invited Speakers

Programme

SATURDAY 7TH MAY 2022

16:00 – 16:30

Registration & Refreshments

 

16:30 – 16:40

Opening Comments

 

Mitochondria in Cell Death and Disease
Session Chair: Henning Walczak & Michael Bergmann

16:40 – 17:25

Navdeep Chandel 
Northwestern University

Opening Keynote Lecture:

MITOCHONDRIA AS SIGNALING ORGANELLES

 

17:25 – 17:55

Maria Eugenia Soriano
University of Padua
 

A COMPENDIUM OF COMPLEXOME CHANGES DURING MITOCHONDRIAL REMODELING FOR FUNCTIONALIZATION OF HIGH MOLECULAR WEIGHT COMPLEXES

 

17:55 – 18:10

Aurora Maracani
University of Padua

THE ASPARTATE-GLUTAMATE CARRIER ORCHESTRATES OPTIC ATROPHY1 MACROMOLECULAR ASSEMBLY AND MITOCHONDRIAL CRISTAE MORPHOLOGY

 

18:10 – 18:40

Refreshments

 

18:40 – 19:10

Atan Gross
Weizmann Institute of Science

Mitochondria metabolism and apoptosis: how do they connect?

 

19:10 – 19:25

Roger Smith
Northwestern University

HSF2 COOPERATES WITH HSF1 TO DRIVE A TRANSCRIPTIONAL PROGRAM CRITICAL FOR THE MALIGNANT STATE

 

19:25 – 19:55

Luca Scorrano
University of Padua

KEEPING MITOCHONDRIA IN SHAPE: A MATTER OF CELL LIFE AND DEATH

 

20:00

Group Dinner

 

SUNDAY 8TH MAY 2022

07:00 – 08:30

Breakfast at Leisure

Tumor Metabolism and Cell Intrinsic Pathways
Session Chair: Navdeep Chandel & Mads Daugaard

08:30 – 09:00

Gina DeNicola
Moffitt Cancer Center

NRF2 AND CYSTEINE METABOLISM

09:00 – 09:15

Alex Colville
Stanford University

DEATH-SEQ, A HIGH-THROUGHPUT SCREENING TECHNIQUE TO STUDY REGULATORS OF CELL DEATH

09:15 – 09:45

Scott Lowe
Memorial Sloan Kettering Cancer Center

IMMUNE SURVEILLANCE OF SENESCENT CELLS

09:45 – 10:15

Claudio Mauro
University of Birmingham

UNDERSTANDING THE LONG-LASTING EFFECTS OF SATURATED FATTY ACIDS ON THE ADAPTIVE IMMUNE RESPONSE

10:15 – 10:45

Group Photo & Refreshments

10:45 – 11:15

Davide Ruggero
University of California, San Francisco

LIVING A LEAN LIFE: TRANSLATION CONTROL IN OBESITY AND KETOGENESIS

11:15 – 11:30

Jarryd Boath
Peter MacCallum Cancer Centre

CHRONIC ORAL EPITHELIAL BARRIER DYSFUNCTION FOSTERS MICROBIAL IMBALANCES AND PROMOTES INFLAMMATION-DRIVEN HYPERPLASIA AND CARCINOMA OVER TIME

11:30 – 12:00

Francesco Cecconi
Danish Cancer Society

AUTOPHAGY AND E3 LIGASES: TOP GUARDIANS OF CELL CYCLE

12:00 – 12:30

Peter Kreuzaler
The Francis Crick Institute & University of Cologne

Vitamin B5 oncogenic metabolism and tumour progression in breast cancer

12:30 – 16:30

Lunch at Leisure & Free Time

Cell Death and Inflammation in Signaling and Disease
Session Chair: Luca Scorrano & Maria Eugenia Soriano

16:30 – 17:00

Henning Walczak
University of Cologne & University College London

DEATH RECEPTORS AND THEIR LIGANDS IN INFLAMMATION AND DISEASE

17:00 – 17:30

Mads Daugaard
University of British Columbia

A GENOME-WIDE CRISPR SCREEN REVEALS DEATH AND SURVIVAL PATHWAYS THAT DETERMINE THE RESPONSE TO CISPLATIN

17:30 – 17:45

Claudia Meyer
UKD Dresden

RUBICON-DEFICIENCY SENSITIZES MICE TO MIXED-LINEAGE KINASE DOMAIN LIKE (MLKL)-MEDIATED KIDNEY ISCHEMIA-REPERFUSION INJURY

17:45 – 18:15

Refreshments

18:15 – 18:30

Anne Griesbeck
Sciomics

PRECISION MEDICINE THROUGH INNOVATIVE BIOMARKER SIGNATURES

18:30 – 19:00

Mathieu Bertrand
VIB-UGent Center for Inflammation Research

AN UNCONVENTIONAL LYSOSOMAL TARGETING PATHWAY PREVENTS TNF CYTOTOXICITY

Cancer Biology and the Tumor Microenvironment I
Session Chair: Claudio Mauro

19:00 – 19:15

Giacomo Milletti
Bambino Gesù Children Hospital

AMBRA1 REGULATES CELL PROLIFERATION AND CELL DEATH IN SHH MEDULLOBLASTOMA

19:15 – 19:30

Karthik Vasan
Northwestern University

TARGETING MITOCHONDRIAL GLRX5 FOR CANCER THERAPY

19:30

Dinner at Leisure

MONDAY 9TH MAY 2022

07:00 –09:00

Breakfast at Leisure

Cancer Biology and the Tumor Microenvironment II
Session Chair: Scott Dixon & Tom Vanden Berghe

09:00 –09:30

Gianmaria Liccardi
University of Cologne

MITOTIC CELL DEATH: A CYCLE FULL OF CINS AND SURPRISES

09:30 – 10:00

Michael Bergmann 
Medical University of Vienna

Complex primary tumor cultures to dissect immunogenic effect of therapy

10:00 – 10:30

Refreshments

Ferroptosis in Health and Disease
Session Chair: Francesco Cecconi & Gina DeNicola

10:30 – 11:00

Raphaël Rodriguez
Institut Curie

DISCOVERY OF A DRUGGABLE COPPER-SIGNALING PATHWAY THAT DRIVES CELL PLASTICITY AND INFLAMMATION

11:00 – 11:30

Scott Dixon
Stanford University

A PALMITOYLATION-DEPENDENT NON-APOPTOTIC CELL DEATH MECHANISM

11:30 – 11:45

Wulf Tonnus
Technische Universität Dresden

GASDERMINS PROTECT AGAINST NECROPTOTIC CELL DEATH IN MURINE ACUTE KIDNEY INJURY

11:45 – 16:15

Lunch at Leisure & Free Time

16:15 – 16:30

Jason Rodencal
Stanford University

MBOAT1 LINKS CDK4/6 ACTIVITY TO FERROPTOSIS SENSITIVITY

16:30 – 16:45

Behrouz Hassannia
UAntwerp/VIB-UGent

PHENOTYPIC SCREENING IDENTIFIES NOVEL MODULATORS OF FERROPTOSIS

16:45 – 17:15

Anne von Mässenhausen
University Hospital Carl Gustav Carus

DEXAMETHASONE SENSITIZES TO FERROPTOSIS BY GLUCOCORTICOID RECEPTOR-INDUCED DIPEPTIDASE-1 EXPRESSION AND GLUTATHIONE DEPLETION

17:15 – 17:30

Emily Van San
VIB-UGent Center for Inflammation Research

THERAPEUTIC TARGETING OF FERROPTOSIS IN MULTIPLE SCLEROSIS

17:30 – 18:00

Refreshments

18:00 – 18:30

Andreas Linkermann 
UKD Dresden

THE MALE VS THE FEMALE: FAILURE TO PROTECT FROM FERROPTOSIS EXPLAINS MALE HYPERSENSITIVITY TO ACUTE KIDNEY TUBULAR NECROSIS

18:30 – 19:00

Tom Vanden Berghe University of Antwerp

FERROPTOSIS TARGETING, LIFESAVING @ INTENSIVE CARE UNITS?

19:00 – 19:45

Douglas R. Green
St. Jude Children’s Research Hospital

Closing Keynote Lecture:
PERSISTER ACT: NEAR DEATH EXPERIENCES IN CANCER CELLS

19:45 – 19:55

Closing Comments

20:00

Gala Dinner

TUESDAY 10TH MAY 2022

Departures
*Hotel Checkout is at midday*

Supported by

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Venue & Location

Fiesta Americana Condesa Cancun All Inclusive

This stylish hotel features contemporary Mexican architecture, including one of the largest and most impressive thatched-roof "palapas" in the entire country. There are cultural activities, arts and crafts and sports programs to keep you constantly entertained, plus time to relax and enjoy the Mayan culture, soak up the Caribbean sunshine and revel in the international ambiance that settles in after the sun goes down.

Throughout your stay delegates will enjoy a full meal plan, inclusive of beverages. Take your pick from the aromatic Asian delights at Kaumbu, traditional fare at El Mexicano, delicious international cuisine at Kalmia Buffet or perhaps sample the sumptuous Italian dishes at Rosato. There are also several other dining opportunities such as the Cevichería, Pizzeria, Sushi Corner, pool and lounge bar areas. The Gala Night with either a Mayan or Caribbean theme takes place on the third evening of the conference with a mouth-watering feast of local cuisine, an open bar and amazing local entertainment.  We welcome all delegates and their accompanying persons to the Gala Night – a truly fun filled night not to be missed!

Hotel Facilities

- Lagoon Pool
- Extensive Health Club and Spa
- Complimentary Wi-Fi in guest rooms and throughout hotel and conference areas

General Information

Venue Rating

★ ★ ★ ★ ★

Currency

US Dollar (USD)

Address

Fiesta Americana Condesa Cancún All Inclusive Blvd. Kukulcan km 16.5 Zona Hotelera 77500 Cancun Q.R. Mexico

Nearest Airport

Cancun International Airport

Location

Cancun is a delightful combination of natural beauty, islands, ecological reserves and white sandy beaches. However, besides sun, sand and sea, this destination also offers an infinite variety of underwater activities to choose from: the diving, snorkelling and fishing here are outstanding and you will find an undersea world packed with tropical fish that live on the second largest barrier reef in the world. Sports enthusiasts might choose one of the many eco-tourism activities, such as cycling or hiking through the tropical forest or kayaking through mangroves, or something a little more adventuresome, like zip lining through the treetops.

Apart from the more well-known ancient Mayan archealogical sites such as Tulum, Cobá and Chichén Itzá you may like to visit the Aktun Chen caverns, voted one of the Top 10 underwater walks by National Geographic described as a truly magical experience.

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Media Partners

If you're interested in sponsoring this conference please contact us.

Conference Manager

Jack Peters

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