Synopsis
Mitochondria act at the interface of numerous processes critical for cellular function and organismal health. Long recognized as the powerhouses of the cell, mitochondria are emerging as hubs for cellular metabolism, redox balance, signalling, gene expression, detoxification, and ion homeostasis. Mitochondrial maintenance is critical for proper development and function of cells and tissues, and mitochondrial dysfunction underlies numerous disease processes ranging from severe childhood mitochondrial disorders, to heart disease, neurodegenerative disorders, cancer, and aging itself. This conference will bring together scientists and clinicians with expertise in a breadth of mitochondrial biology to explore topics at the interface of basic and translational biology. Mitochondrial basic mechanisms of organelle regulation, mitochondrial mechanisms of disease, cutting edge technologies, and interventional strategies will be emphasized in interactive scientific sessions.
Confimed Speakers
Kivanc Birsoy (Rockefeller University)
Nav Chandel (Northwestern Medicine)
MITOCHONDRIA AS SIGNALING ORGANELLES
Edward Chouchani (Harvard University / Dana-Farber Cancer Institute)
David Finlay (Trinity College Dublin)
Susan Kaech (Salk Institute)
Naama Kanarek (Harvard Medical School)
METABOLIC VULNERABILITY OF LEUKEMIA IN THE BRAIN
Pekka Katajisto (University of Helsinki)
Samantha Lewis (University of California, Berkeley)
THE MITOCHONDRIAL CENTRAL DOGMA IN HOMEOSTASIS AND STRESS
Luke O'Neill (Trinity College Dublin)
ADVENTURES WITH ITACONATE, THE MITOCHONDRIAL METABOLITE THAT KEEPS ON GIVING
Natasha Pavlova (University of Utah)
David Pagliarini (Washington University in St. Louis)
Erika Pearce (John Hopkins University)
DELINEATING THE METABOLIC SIGNALS THAT REGULATE IMMUNE CELL DIFFERENTIATION AND FUNCTION
Josh Rabinowitz (Princeton University)
Jared Rutter (University of Utah)
Dylan Ryan (University of Cambridge)
Luca Scorrano (University of Padua)
Shabnam Shalapour (The University of Texas MD Anderson Cancer Center)
Gerald Shadel (Salk Institute)
Celeste Simon (University of Pennsylvania)
THE UREA CYCLE IN HEALTH AND DISEASE
Jessica Spinelli (UMass Chan Medical School)
Target Audience
- Basic scientists studying mechanisms of mitochondrial and cell biology
- Clinicians and translational biologists interested in mitochondrial disease
- Immunologists studying mitochondrial function and the role of mitochondria in immune health and disease
- Scientists studying processes where mitochondria are important (metabolism, aging, cancer, heart function, etc.)
Educational Need
Mitochondria function at the intersection of many important areas of biology and biomedicine, but there are limited opportunities for people studying different areas of biology where mitochondria are important (aging, neurodegenerative disease, inherited disorders, mitochondria disease, heart disease, myopathies and muscular dystrophies, evolutionary biology, obesity, diabetes, kidney disease, etc.) to come together at one meeting. The primary outcome we hope to stimulate is interaction and cross fertilization of ideas between these diverse scientists leading to new collaborations and synergistic advances.
Supported By
Media Partners
If you're interested in sponsoring this conference please contact us.