Registration deadlines

Early Bird - 30 Jan 2025

Talk Submission - 30 Jan 2025

Poster Submission - 08 May 2025

Registration Deadline - 08 May 2025

Register

Conference Manager

Alice Tebbit

Alice Tebbit

2nd Balancing Genome Fidelity & Plasticity Conference

#BGFP25


07 Jul 2025 - 10 Jul 2025

Lisbon, Portugal

Chairs

Agnel Sfeir
Memorial Sloan Kettering Cancer Center
Karlene Cimprich
Stanford University
Dipanjan Chowdhury
Dana-Farber Cancer Institute

Synopsis

While alterations to DNA underlie genome evolution and antibody diversification, genome instability drives many disorders, including cancer, developmental abnormalities, and neurodegeneration. DNA damage and other genome-threatening replication blocks are generally overcome by a number of DNA repair pathways. The choice of DNA repair pathways, specifically the reliance on error-prone vs. error-free is both intriguing and confounding. Moreover, the deregulation of repair pathway choice can trigger pathological processes. In this conference, we will discuss the delicate equilibrium of genome maintenance pathways, addressing how natural processes such as replication and transcription can threaten genome stability, how the genome can be altered in cancer, signatures of genome instability in human disease, and how cells control the inherent plasticity of their replication and repair machinery. We aim to bring together scientists from diverse fields who are interested in understanding the many processes impacting DNA metabolism and the molecular and biophysical principles that maintain the balance between genome stability and plasticity.

Key Sessions

  • Genome Signatures and Evolution
  • Tissue Specific Repair and Mutagenesis
  • Transcription-Replication Driven Mutation
  • Transposable Elements
  • DNA Sensing and Inflammation
  • CRISPR/Cas9 and DNA Repair

Confirmed Invited Speakers

Andrea Ablaser (EPFL)
Karen Adelman (Harvard University)
Kathleen Burns (Dana-Farber Cancer Institute)
Keith Caldecott (University of Sussex)
Alberto Ciccia (Columbia University)
Cecilia Cotta-Ramusino (Tessera Therapeutics)
Titia de Lange (Rockefeller University)
Daniel Durocher (Lunenfeld-Tanenbaum Research Institute)
Marcin Imielinski (NYU Langone Health)
Gaëlle Legube (CBI Toulouse)
John Maciejowski (Memorial Sloan Kettering Cancer Center)
Houra Merrikh (Vanderbilt University)
Serena Nik-Zainal (University of Cambridge)
KJ Patel (University of Oxford)
Nitika Taneja (Erasmus Medical Center)
Alessandro Vindigni (Washington University)
Johannes Walter (Harvard University)
Joanna Wysocka (Stanford University)
Joe Yeeles (MRC Laboratory of Molecular Biomedicine)

Target Audience

The meeting, which addresses fundamental questions that pertain to genome instability, is expected to appeal to basic science researchers, including students and postdocs. In addition, the various topics covered will be of interest to translational and clinical investigators in academic institutions and industry.

Educational Need

Genomic integrity is the foundation of human health with a plethora of diseases emerging from any dysfunction in the cellular machinery that maintains our genome. In this conference we focus on emerging areas in the field of genome biology that have gained significant prominence in recent years, specifically, large scale studies on genome evolution and mutational signatures combined with the interplay of DNA metabolism, RNA metabolism and DNA repair in the context of sub-nuclear compartments. We anticipate that attendees at all levels, students, post-doctoral fellows, and faculty will be exposed to radical new concepts and cutting-edge technology that will define the genome stability field in the upcoming years. The conference is being designed to facilitate interaction of  trainees with senior scientists, and promote scientific collaborations. 

Supported By

Silver
Bronze
Media Partners
If you're interested in sponsoring this conference please contact us.

2nd Balancing Genome Fidelity & Plasticity Conference

#BGFP25


07 Jul 2025 - 10 Jul 2025

Lisbon, Portugal

Chairs

Agnel Sfeir
Memorial Sloan Kettering Cancer Center
Karlene Cimprich
Stanford University
Dipanjan Chowdhury
Dana-Farber Cancer Institute

Speakers

Invited Speakers

Andrea Ablasser

EPFL

Karen Adelman

Harvard University

Kathleen Burns

Dana-Farber Cancer Institute

Keith Caldecott

University of Sussex

Alberto Ciccia

Columbia University

Cecilia Cotta-Ramusino

Tessera Therapeutics

Titia de Lange

Rockefeller University

Daniel Durocher

Lunenfeld-Tanenbaum Research Institute

Marcin Imielinski

NYU Langone Health

Gaƫlle Legube

CBI Toulouse

John Maciejowski

Memorial Sloan Kettering Cancer Center

Houra Merrikh

Vanderbilt University

Serena Nik-Zainal

University of Cambridge

KJ Patel

University of Oxford

Nitika Taneja

Erasmus Medical Center

Alessandro Vindigni

Washington University

Johannes Walter

Harvard University

Joanna Wysocka

Stanford University

Joe Yeeles

MRC Laboratory of Molecular Biology

Supported By

Silver
Bronze
Media Partners
If you're interested in sponsoring this conference please contact us.

2nd Balancing Genome Fidelity & Plasticity Conference

#BGFP25


07 Jul 2025 - 10 Jul 2025

Lisbon, Portugal

Chairs

Agnel Sfeir
Memorial Sloan Kettering Cancer Center
Karlene Cimprich
Stanford University
Dipanjan Chowdhury
Dana-Farber Cancer Institute

Programme

Although the programme has not yet been released, we are able to confirm that the conference should begin no earlier than 14:00 with opening comments on Monday 07 July 2025. The conference will conclude no later than 12:30 on Thursday 10 July 2025.


Supported By

Silver
Bronze
Media Partners
If you're interested in sponsoring this conference please contact us.

2nd Balancing Genome Fidelity & Plasticity Conference

#BGFP25


07 Jul 2025 - 10 Jul 2025

Lisbon, Portugal

Chairs

Agnel Sfeir
Memorial Sloan Kettering Cancer Center
Karlene Cimprich
Stanford University
Dipanjan Chowdhury
Dana-Farber Cancer Institute

Prices

Ticket Type Early Bird Full Price
Single
Choose this option if you will be attending the conference alone, or if you will bring accompanying guests that will not attend the meeting.
ā‚¬1981 ā‚¬2077
Shared
Choose this option if you wish to share with a colleague who is also attending the conference, or if you wish to be paired with another attendee of the same sex.
ā‚¬1784 ā‚¬1880
Student
Choose this option if you are a student. Please note all students will be paired with another attendee of the same sex if a room sharer is not specified. If you wish to have your own room, please register under the Single option.
ā‚¬1038 ā‚¬1038
Additional Person
This is the cost for an additional adult or child to join you in the same room, for the entire conference period. Accompanying persons are not permitted access to the conference. If you wish to extend your stay, please see our 'Extra night' prices.

Adult

ā‚¬825

Child

ā‚¬455

Extra nights
Prices are per person.

Adult

ā‚¬190

Child

ā‚¬61


All registration fees include 3 nights accommodation and meals during the conference period. Exact inclusions are detailed below.

What's Included in our Registration Fees?

Our registration fees are inclusive of the following during the conference period only:

- Conference registration
- 3 nights’ fixed accommodation (07, 08, 09 July 2025) on a single or shared basis
- Buffet breakfast
- Buffet lunch with soft drinks, beer and wine
- Buffet dinner with soft drinks, beer and wine
- Gala Dinner with soft drinks, beer and wine
- Complimentary WIFI in both conference rooms and your guest room

What's Included in our Accompanying Adult Fees?

Our accompanying adult fees are inclusive of the following during the conference period only:

- 3 nights’ fixed accommodation (07, 08, 09 July 2025) on a shared basis with a conference participant
- Buffet breakfast
- Buffet lunch with soft drinks, beer and wine
- Buffet dinner with soft drinks, beer and wine
- Gala Dinner with soft drinks, beer and wine
- Complimentary WIFI in guest room

Important Note: Accompanying persons are not permitted access to the conference. Meals are only available during the times listed in the conference programme and accompanying guests must dine with the group.

What's Included in our Accompanying Child Fees?

Our accompanying child fees are inclusive of the following during the conference period only:

- 3 nights’ fixed accommodation (07, 08, 09 July 2025) on a shared basis with the parent/s
- Buffet breakfast 
- Buffet lunch with soft drinks
- Buffet dinner with soft drinks
- Gala Dinner with soft drinks
- Complimentary WIFI in guest room
- A crib (0-3 years old) or roll out bed (4-17 years old)

Important Note: Accompanying child fees are applicable for children aged 12-17 years. Children aged 0-3 years stay free of charge and children aged 4-11 years will be charged a rate of €156.00, inclusive of the above package. If your child is aged 0-11 years, please contact us so we can adjust the invoices relating to your child/children. Please kindly ensure your child/children are supervised at all times during conference and related events. Childcare services may be available, please contact Alice for further information.

What's Included in our Extra Night Fees?

- 1 night’s accommodation for 1 person
- Buffet breakfast
- Complimentary WIFI in your guest room

Important Note: Extra night child fees are applicable for children aged 12-17 years. Children aged 0-11 years stay free of charge, inclusive of the above package. If your child is aged 0-11 years, please contact us so we can adjust the invoices relating to your child/children.

Prices and hotel availability are subject to change without notice.

Supported By

Silver
Bronze
Media Partners
If you're interested in sponsoring this conference please contact us.

2nd Balancing Genome Fidelity & Plasticity Conference

#BGFP25


07 Jul 2025 - 10 Jul 2025

Lisbon, Portugal

Chairs

Agnel Sfeir
Memorial Sloan Kettering Cancer Center
Karlene Cimprich
Stanford University
Dipanjan Chowdhury
Dana-Farber Cancer Institute

Grants

2nd Balancing Genome Fidelity & Plasticity Conference

#BGFP25


07 Jul 2025 - 10 Jul 2025

Lisbon, Portugal

Chairs

Agnel Sfeir
Memorial Sloan Kettering Cancer Center
Karlene Cimprich
Stanford University
Dipanjan Chowdhury
Dana-Farber Cancer Institute

Supported By

Silver
Bronze
Media Partners
If you're interested in sponsoring this conference please contact us.

2nd Balancing Genome Fidelity & Plasticity Conference

#BGFP25


07 Jul 2025 - 10 Jul 2025

Lisbon, Portugal

Chairs

Agnel Sfeir
Memorial Sloan Kettering Cancer Center
Karlene Cimprich
Stanford University
Dipanjan Chowdhury
Dana-Farber Cancer Institute

LinkedIn forum

Bringing together the global community of researchers and scientists interested in the study of DNA. Relevant specialties are wide-ranging, reflecting the importance of DNA Research in many aspects of health and disease, including; DNA Repair, DNA Replication, DNA Damage, Cancer, Chromosomal Instability, RNA and Nucleic Acids.

The group is open to all and is intended as a networking forum for past, present and future participants of Fusion Conferences as well as those interested in the related topics.

Join our group

Supported By

Silver
Bronze
Media Partners
If you're interested in sponsoring this conference please contact us.

2nd Balancing Genome Fidelity & Plasticity Conference

#BGFP25


07 Jul 2025 - 10 Jul 2025

Lisbon, Portugal

Chairs

Agnel Sfeir
Memorial Sloan Kettering Cancer Center
Karlene Cimprich
Stanford University
Dipanjan Chowdhury
Dana-Farber Cancer Institute

Venue

Dolce CampoReal Lisboa

Located in Torres Vedras, just a 30-minute drive from Lisbon, Dolce CampoReal Lisboa offers unique tranquillity, as a result of its idyllic environment. The hotel offers stunning views over the golf course, vineyards and the extraordinary landscape of Socorro and Archeira Mountains.

The hotel has three restaurants to provide a variety of gastronomic choices, and two bars including one beside the outdoor pool.

Hotel Facilities

  • Complimentary Wi-Fi in guest rooms and throughout hotel and conference areas
  • Indoor heated swimming pool
  • Outdoor swimming pool with Jacuzzi
  • Spa
  • Gym
  • Golf course
  • 2 Tennis courts

Venue Rating

Currency

Euro (EUR)

Address

R. do Campo (Campo Real) 2565-770 Portugal

Nearest Airport

Lisbon Portela Airport

Location

The Dolce CampoReal Lisboa is nestled between the vineyards and the extraordinary landscape of the Socorro and Archeira Mountains.

Lisbon is only a short 30-minute drive away. The Portuguese capital is constantly recognised as one of the greatest cities in the world, a claim confirmed by the “Lonely Planet Guides", who named Lisbon one of the world’s top 10 cities. Lisbon in one of the world’s oldest cities, predating the likes of London, Rome and Paris by hundreds of years. Hillsides covered in tumbledown houses and a mix of baroque and neoclassical buildings, including cathedrals and palaces, make up Lisbon’s skyline. The city is a combination of old and new, with beautiful modern buildings constructed near renovated historical landmarks and ruins.

Supported By

Silver
Bronze
Media Partners
If you're interested in sponsoring this conference please contact us.

2nd Balancing Genome Fidelity & Plasticity Conference

#BGFP25


07 Jul 2025 - 10 Jul 2025

Lisbon, Portugal

Chairs

Agnel Sfeir
Memorial Sloan Kettering Cancer Center
Karlene Cimprich
Stanford University
Dipanjan Chowdhury
Dana-Farber Cancer Institute

Transportation

Dolce CampoReal Lisboa, Torres Vedras is approximately a 30-minute journey from Lisbon Portela Airport.

Taxis

Taxis are available outside the airport, but we would strongly recommend you pre-book your airport transfer with one of the many private transfer companies that are available. The Dolce CampoReal Lisboa is located outside of the city zone and a pre-booked transfer will be a cheaper option than a taxi taken from the airport taxi rank.

Uber also operate in and around Lisbon and there are other Portuguese taxi-hailing apps such as Bolt, MyTaxi, TaxisLisboa and Coop Taxis, all offering reasonable rates.

Further information regarding pre-booked transfers will be made available closer to the conference dates.

Supported By

Silver
Bronze
Media Partners
If you're interested in sponsoring this conference please contact us.

2nd Balancing Genome Fidelity & Plasticity Conference

#BGFP25


07 Jul 2025 - 10 Jul 2025

Lisbon, Portugal

Chairs

Agnel Sfeir
Memorial Sloan Kettering Cancer Center
Karlene Cimprich
Stanford University
Dipanjan Chowdhury
Dana-Farber Cancer Institute

Local Activities

There are various on-site activities available. These include:

- Indoor and 2 outdoor swimming pools
- Fitness centre, available 24h
- Tennis courts
- Donald Steel designed Golf Course – 18 holes Par 72
- Miguel Athayde Equestrian Centre 
- Mandalay Wellness & Spa with 7 treatment rooms
- Kids Club – The hotel will provide details of daily activities for children
- Center “Clube Aventura” for outdoor activities such as Giant Balls, Aquaball, Stand Up Paddle, Archery, Slackline, Water Slide

**Please note, there may be a charge to participate in some of the above activities.

Should you have time to venture off-site, the Oeste Region and Torres Vedras have a distinctive cultural heritage, rich history, 20 km of coastal area, and a commitment to environmental awareness, accessibility and biodiversity. Below are a few suggestions:

- Monastery of Alcobaça, a UNESCO World Heritage site
- Historical route of the lines of Torres Vedras
- Day trip to Óbidos
- Royal Palace and Convent of Mafra
- Tapada Nacional de Mafra
- Mountain biking along the Santa Cruz to Torres Vedras Loop
- Birdwatching at the Tajus Estuary Nature Reserve
- Jeep tours in and around Torres Verdras

Supported By

Silver
Bronze
Media Partners
If you're interested in sponsoring this conference please contact us.

2nd Balancing Genome Fidelity & Plasticity Conference

#BGFP25


07 Jul 2025 - 10 Jul 2025

Lisbon, Portugal

Chairs

Agnel Sfeir
Memorial Sloan Kettering Cancer Center
Karlene Cimprich
Stanford University
Dipanjan Chowdhury
Dana-Farber Cancer Institute

Group Activities

Group activities will be announced here soon.

Supported By

Silver
Bronze
Media Partners
If you're interested in sponsoring this conference please contact us.

2nd Balancing Genome Fidelity & Plasticity Conference

#BGFP25


07 Jul 2025 - 10 Jul 2025

Lisbon, Portugal

Chairs

Agnel Sfeir
Memorial Sloan Kettering Cancer Center
Karlene Cimprich
Stanford University
Dipanjan Chowdhury
Dana-Farber Cancer Institute

Childcare

Supported By

Silver
Bronze
Media Partners
If you're interested in sponsoring this conference please contact us.

2nd Balancing Genome Fidelity & Plasticity Conference

#BGFP25


07 Jul 2025 - 10 Jul 2025

Lisbon, Portugal

Chairs

Agnel Sfeir
Memorial Sloan Kettering Cancer Center
Karlene Cimprich
Stanford University
Dipanjan Chowdhury
Dana-Farber Cancer Institute

Oral Presenters

We have several oral opportunities available at this meeting. To be considered for a talk, please register for the conference and upload your abstract when prompted to do so. You will be able to monitor the status of your abstract through your Fusion account and you will also receive an email if you are successful or unsuccessful.

If you are unable to register for the conference for any reason, but still wish to submit an abstract for consideration, please email the Conference Manager directly.

Please use the abstract template provided (see below) and ensure your abstract is no longer than one page in length.

If you are accepted for a talk, we recommend you check our website regularly as the conference approaches. Regular programme updates will be released under the ‘Programme’ tab on the conference website.

Your Presentation

On the day of your presentation please make yourself known to our AV technician who will be present in the conference room. We advise running through your presentation at least 30minutes prior to your session commencing to ensure your slides and any videos or animations appear as expected. We prefer our speakers to run their presentation from the master PC or Mac, however, if you prefer to use your own laptop then please notify us prior to the session. A HDMI or VGA cable is usually available on the podium.

Our AV technician will apply your microphone and provide a combined slide advancer and laser pointer.

We ask all speakers to adhere to their time slots and respect their fellow presenters. A visual traffic light aide will be available to warn presenters as their time decreases.

Please make sure your presentation adheres to the following guidelines.

Aspect Ratio: On Screen Show (16:9)
File Type: Please save your presentation in PPT, PPTS or Keynote format.

Download Abstract Template

Supported By

Silver
Bronze
Media Partners
If you're interested in sponsoring this conference please contact us.

2nd Balancing Genome Fidelity & Plasticity Conference

#BGFP25


07 Jul 2025 - 10 Jul 2025

Lisbon, Portugal

Chairs

Agnel Sfeir
Memorial Sloan Kettering Cancer Center
Karlene Cimprich
Stanford University
Dipanjan Chowdhury
Dana-Farber Cancer Institute

Posters

We have several poster opportunities available at this meeting. To be considered for a poster presentation, please register for the conference and upload your abstract when prompted to do so. You will be able to monitor the status of your abstract through your Fusion account and you will also receive an email if you are successful or unsuccessful.

Please use the abstract template provided (see below) and ensure your abstract is no longer than one page in length.

Our poster boards can accommodate a maximum poster size of A0 (1189H x 841W mm), portrait in orientation. Posters exceeding this size may not fit on the poster boards provided and therefore we may be unable to display your poster, so please kindly keep to these measurements.

Displaying & Presenting Your Poster

Please bring your poster to registration and hand this to a member of the Fusion team. They will advise of your poster number and display your poster for you. 

Your poster will remain on display for the duration of the conference, allowing presenters to take advantage of the refreshment breaks and free time for valuable networking opportunities, in addition to the official poster session.

Please check the programme and note the date and time of the poster session(s). Your poster will be judged during the poster session and prizes will be awarded at the Gala Dinner.

Posters will be taken down by the Fusion team and will be ready for collection at the Fusion desk on the final day of the conference.

Download Abstract Template

Supported By

Silver
Bronze
Media Partners
If you're interested in sponsoring this conference please contact us.