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Fibroblast Growth Factors in Development and Repair
04 Feb - 07 Feb 2015
Cancun, Mexico
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Saverio Bellusci
Justus-Liebig-Universitaet Giessen, ECCPS
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David Ornitz
Washington University
Early Bird - Expired • Talk Submission - Expired • Poster Submission - Expired • Registration & Payment Deadline - Expired
Report
This first Fusion conference on Fibroblasts Growth Factors in Development and Repair took place in Cancun Mexico, from February 04 through February 07, 2015. The meeting was chaired by Prof. David Ornitz (Washington University, St Louis, USA) and Prof. Saverio Bellusci (Justus Liebig University, Giessen, Germany).
The invited Faculty included Prof. Dr. Lin Chen (Center of Bone Metabolism and Repair, China), Dr. Richard Grose (The Barts Cancer Institute, UK), Dr. Mohammad Hajihosseini (University of East Anglia, UK), Prof. Lynn E. Heasley (University of Colorado Denver, USA), Dr. Laurence Legeai-Maillet (Hopital Necker-Enfants Malades, France), Prof .Xiokun Li (Wenzhou Medical University, China), Prof. Susanne Mansour (University of Utah, USA), Prof. Philippe Soriano (The Mount Sinai Hospital, USA) and Prof. Dr. Sabine Werner (ERTH, Zurich, Switzerland).
In addition, other speakers, both junior, mid-level, and senior scientists were selected from the submitted abstracts. We had a good ratio of speakers both in terms of gender and seniority, with the priority given to junior to mid level scientists.
This meeting was organized on a relatively short notice but we were successful both in attracting high level faculty speakers and a diverse repertoire of participants from multiple nationalities. We were also able to attract substantial funding allowing travel awards to be given to all attending students, postdocs, and junior faculty. The participants at this meeting primarily work in the field of FGFs in cancer, neurobiology, regeneration and disease, and organogenesis. In addition, a joint session was organized with the fusion conference on Musculoskeletal Development and Regeneration taking place at the same time as the FGF conference. This was a wonderful opportunity to allow additional networking and cross fertilization of ideas between two overlapping but related fields of research.
The conference venue allowed for a very relaxed atmosphere for discussion, networking, and setting up collaborations. Participation of most of the attendees to the discussions following the talks was outstanding and these often continued into the free time in the afternoons and evenings. Overall, high quality speakers presented state of the art data and the posters were thoroughly discussed.
The fusion conference staff was outstanding and very professional. Participants were generally very impressed with the quality of the venue and the organization of the meeting. There was considerable enthusiasm from the participants to hold another Fusion meeting in 2017 on the same topic and in a location that remains to be defined.
Synopsis
The first in the series of the Fibroblast Growth Factors in Development and Repair Fusion conference.
The major goal of this Fusion Conference is to bring together in a single forum the diverse group of researchers who study fibroblast growth factor (FGF) signaling. This will provide a unique opportunity to discuss new results and to target future research areas.
Key Sessions
- The mechanisms by which FGF signaling governs organogenesis and tissue patterning during embryonic development.
- The role of FGF signaling in adult tissue homeostasis, repair, regeneration, and angiogenesis.
- Aberrant FGF signaling in developmental/hereditary diseases including including skeletal, cardiovascular, neurological, respiratory, digestive, genitourinary, and endocrine disorders.
Target Audience
Reflecting the pleiotropic functions of FGF signaling in human biology, FGF researchers encompass a wide range of scientific disciplines, including structural biologists, biochemists, cell biologists, endocrinologists, developmental biologists, geneticists, pharmacologists and clinicians.
2015 Fibroblast Growth Factors Poster Prize
The conference chairs will be awarding 3 poster prizes for the best poster display and presentation. To be in with a chance of winning, submit your poster by 21 November 2014. The winners will be selected shortly after the Poster Session and each winner will receive a $250 cheque!
Confirmed Plenary speakers
Prof. Dr. Lin Chen
Center of Bone Metabolism and Repair
THE ROLE OF FGFR3 IN CARTILAGE DISEASES
Dr. Richard Grose
The Barts Cancer Institute
MECHANISMS OF FGFR INHIBITOR RESISTANCE IN FGFR-DRIVEN CANCER
Dr. Mohammad Hajihosseini
University of East Anglia
FGF10 FUNCTION IN THE ADULT BRAIN – FROM NEURAL STEM CELLS TO THE CONTROL OF APPETITE/ ENERGY BALANCE
Prof. Lynn E. Heasley
University of Colorado Denver
AUTOCRINE SIGNALING THROUGH NON-MUTATED FGFR1 IN HUMAN CANCERS
Prof. Matthew Hoffman
National Institutes of Health
FGF-DEPENDENT WNT SIGNALS REGULATE EPITHELIAL PROGENITOR-NEURONAL INTERACTIONS DURING DEVELOPMENT
Dr. Laurence Legeai-Mallet
Hôpital Necker-Enfants Malades
FROM FUNCTIONAL STUDIES TO THERAPEUTIC APPROACHES FOR FGFR3-RELATED DISORDERS
Prof. Xiaokun Li
Wenzhou Medical University
Prof. Suzanne Mansour
University of Utah
FGF SIGNALING IN INNER EAR DEVELOPMENT
Prof. Philippe Soriano
The Mount Sinai Hospital
FGF SIGNALING PATHWAYS IN DEVELOPMENT
Prof. Dr. Sabine Werner
ETH Zürich
FGF SIGNALING IN EPITHELIAL HOMEOSTASIS, INJURY AND REPAIR
Confirmed Invited Speakers
Dr. Alvaro Ingles Prieto
Institute of Science and Technology Austria
LIGHT-CONTROLLED RTKS ALLOW CELL-BASED EXPLORATION OF MAPK/ERK PATHWAY INHIBITORS
Prof. David Warburton
Childrens Hospital Los Angeles
FGF SIGNALING: PUSH ME PULL YOU?
Confirmed Speakers
Chairs
Saverio Bellusci
Chair for Lung Matrix Remodeling, Justus-Liebig-Universitaet Giessen, ECCPS
David Ornitz
Professor, Washington University
Plenary Speakers
Mohammad K Hajihosseini
Senior Lecturer in Neuroscience, University of East Anglia
Philippe Soriano
Professor, Icahn School of Medicine at Mt. Sinai
Suzanne Mansour
Professor, University of Utah
Sabine Werner
Prof. Dr., ETH Zurich Institute of Molecular Health Sciences
Richard Grose
Reader, Queen Mary, University of London
Laurence Legeai-Mallet
Director of Research, Imagine Institute-Inserm U1163
Matthew Hoffman
Senior Investigator, National Institutes of Health
Lynn Heasley
Professor, University of Colorado Anschutz Medical Campus
Lin Chen
Professor, Trauma Center,Daping Hospital,Third Military Medical University
Xiaokun Li
Vice president , Wenzhou Medical University
Programme
Wednesday 4th February 2015 |
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12:00 – 15:00 |
Registration |
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13:00 -14:30 |
Welcome Lunch |
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Cancer Session |
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14:45 – 15:00 |
Opening Comments |
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15:00 – 15:35 |
Lynn Heasley |
AUTOCRINE SIGNALING THROUGH NON-MUTATED FGFR1 IN HUMAN CANCERS |
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15:35 – 15:55 |
Debbie Cunningham |
CHARACTERISATION OF PHOSPHORYLATION EVENTS DOWNSTREAM OF AMPLIFIED FGFR2 IN THE BREAST CANCER CELL LINES SUM52 AND MFM223 |
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15:55 – 16:30 |
Dina Ron |
THE TUMOR SUPPRESSOR, SEF, REGULATES HUMAN EPIDERMIS HOMEOSTASIS THROUGH MULTIPLE MECHANISMS INVOLVING FGF AND PRO-INFLAMMATORY CYTOKINES |
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16:30 – 17:00 |
Refreshments |
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17:00 – 17:20 |
Regina Irschick |
MODULATION OF FGFR1 AND FGF2 TRAFFICKING IN HUMAN GLIOMA CELLS |
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17:20 – 17:55 |
Fen Wang |
TYPE 2 FIBROBLAST GROWTH FACTOR RECEPTOR SIGNALING IS REQUIRED FOR PRESERVING STEMNESS AND PREVENTING DIFFERENTIATION OF PROSTATE STEM CELLS |
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18:00 – 19:30 |
Dinner at Leisure |
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Cancer Session |
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19:30 – 20:05 |
Richard Grose |
MECHANISMS OF FGFR INHIBITOR RESISTANCE IN FGFR-DRIVEN CANCER |
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20:05 – 20:25 |
Alvaro Ingles-Prieto |
LIGHT-CONTROLLED RTKS PERMIT CELL-BASED SCREEN OF SMALL MOLECULES |
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20:25 |
Poster Viewing |
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Thursday 5th February 2015 |
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07:00 -08:30 |
Breakfast |
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Brain Session |
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08:30 – 09:05 |
Ivor Mason |
FGF REGULATION OF CONNECTIVITY IN THE DEVELOPING VERTEBRATE BRAIN |
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09:05 -09:40 |
Lars Klimaschewski |
NOVEL APPROACHES TO SPEED UP LONG-DISTANCE AXON REGENERATION BY ENHANCED FGFR1 SIGNALLING |
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09:40 – 10:15 |
Mohammad Hajihosseini |
FGF10 FUNCTION IN THE ADULT BRAIN – FROM NEURAL STEM CELLS TO THE CONTROL OF APPETITE/ ENERGY BALANCE |
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10:15 – 10:45 |
Refreshments |
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Brain Session |
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10:45 – 11:20 |
Rajesh Ladher |
FGFR1 ROUTES PROTOCADHERIN-15 TO THE CILIUM OF THE INNER EAR HAIR CELLS |
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11:20 – 11:55 |
Suzanne Mansour |
FGF SIGNALING IN INNER EAR DEVELOPMENT: HEARING LOST AND FOUND |
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12:00 – 15:30 |
Lunch at Leisure & Free Time |
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Regeneration and Disease Session |
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15:30 – 16:05 |
Sabine Werner |
ROLES AND MECHANISMS OF ACTION OF FGFS IN SKIN HOMEOSTASIS AND DISEASE |
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16:05 – 16:40 |
Saverio Bellusci |
A BREATH OF FRESH AIR ON THE LUNG MESENCHYME DURING DEVELOPMENT AND DISEASE: LESSONS LEARNT FROM THE FGF AND WNT SIGNALLING |
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16:40 – 17:15 |
Xiaokun Li |
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17:15 – 17:50 |
Anne-Karina Perl |
INTERSTITIAL RESIDENT FIBROBLASTS UNDERGO FUNCTIONAL CHANGES DURING ALVEOLAR REGENERATION |
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18:00 – 19:30 |
Dinner at Leisure |
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Regeneration and Disease Session |
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19:30 – 20:05 |
David Warburton |
FGF SIGNALING: PUSH ME PULL YOU? |
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20:05 – 20:25 |
Robert Guzy |
FIBROBLAST-SPECIFIC FGF SIGNALING IN BLEOMYCIN-INDUCED PULMONARY FIBROSIS |
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20:25 – 20:45 |
Chiko Shimbori |
FIBROBLAST GROWTH FACTOR-1 ATTENUATES TGF-β1-INDUCED LUNG FIBROSIS BY REGULATING TGF-β1 SIGNALING |
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20:45 |
Poster Viewing |
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Friday 6th February 2015 |
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07:00 – 08:30 |
Breakfast |
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Regeneration and Disease Session |
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08:30 – 08:50 |
Stacey House |
CARDIOMYOCYTE-SPECIFIC FIBROBLAST GROWTH FACTOR RECEPTOR SIGNALING PROVIDES ACUTE CARDIOPROTECTION IN A CLOSED-CHEST MODEL OF ACUTE MYOCARDIAL INFARCTION |
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08:50 – 09:10 |
Jo El Schultz |
DIFFERENTIAL CARDIOVASCULAR FUNCTIONS OF FIBROBLAST GROWTH FACTOR-2 PROTEIN ISOFORMS IN ISCHEMIA |
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09:10 – 09:30 |
Yoshikazu Takada |
FGF-INTEGRIN CROSSTALK THROUGH DIRECT INTEGRIN BINDING TO FGF: DEVELOPMENT OF A DOMINANT-NEGATIVE FGF MUTANT (FGF DECOY) |
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09:30 – 09:50 |
Chao Jiang |
DEVELOPMENT OF OLIOSEN-FGF FUSIONS FOR TOPICAL APPLICATIONS |
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09:50 – 10:20 |
Refreshments |
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Development Session |
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10:20 – 10:55 |
Matthew Hoffman |
FGF-DEPENDENT WNT SIGNALS REGULATE EPITHELIAL PROGENITOR-NEURONAL INTERACTIONS DURING DEVELOPMENT |
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10:55 – 11:30 |
Helen Makarenkova |
FGF SIGNALING IN LACRIMAL GLAND DEVELOPMENT, HOMEOSTASIS AND DISEASE |
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11:30 – 11:50 |
Vincent Harley |
CRANIOSYNOSTOSIS WITH XY SEX REVERSAL |
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11:50 – 17:30 |
Lunch at Leisure & Free Time |
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Development Session |
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17:30 – 17:50 |
Ing-Ming Chiu |
EXPRESSION PATTERN OF REPORTER GENES DRIVEN BY HUMAN FGF1 PROMOTER IN TRANSGENIC MICE |
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17:50 – 18:25 |
Philippe Soriano |
FGF SIGNALING PATHWAYS IN DEVELOPMENT |
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18:25 – 18:45 |
Denise Al Alam |
FGF10 IN SMALL INTESTINAL HOMEOSTASIS AND REPAIR |
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18:45 – 20:00 |
Poster Session & Cocktails |
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20:15- 23:00 |
Gala Night, Group Photo & Poster Awards |
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Saturday 7th February 2015 |
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07:00 -08:30 |
Breakfast |
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Joint session with the Fusion conference on Musculoskeletal Development and Regeneration |
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08:30 – 09:05 |
Lin Chen |
DELETION OF FGFR3 IN CARTILAGE LEADS TO CHONDROMA-LIKE LESION |
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09:05 - 09:45 |
Vicki Rosen |
DEVELOPMENTAL REGULATION OF BONE WIDTH BY BMP SIGNALING IS KEY FOR CREATING STRONG BONES |
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09:45 – 10:25 |
Maurizio Pacifici |
DEVELOPMENTAL INSIGHTS INTO THE PATHOGENESIS OF HEREDITARY MULTIPLE EXOSTOSES |
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10:25 – 10:40 |
Refreshments |
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10:40 – 11:10 |
Veronique Lefebvre |
GENOME-WIDE COOPERATIVITY BETWEEN SOX5/6 AND SOX9 DRIVES CHONDROGENESIS |
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11:10 – 11:45 |
David Ornitz |
REGULATION OF SKELETAL GROWTH AND CHONDROGENESIS BY FGFR1 AND FGFR2 SIGNALING IN THE OSTEOPROGENITOR LINEAGE |
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11:45 – 12:05 |
Peter Hurlin |
MUTANT ACTIVATED FGFR3 IMPAIRS ENDOCHONDRAL BONE GROWTH BY PREVENTING SOX9 DOWNREGULATION IN DIFFERENTIATING CHONDROCYTES |
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12:05 – 12:40 |
Laurence Legeai-Mallet |
FROM FUNCTIONAL STUDIES TO THERAPEUTIC APPROACHES FOR FGFR3-RELATED DISORDERS |
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12:40 – 12:50 |
Closing Remarks |
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Contact usVenue & Location
Fiesta Americana Condesa
This stylish hotel features contemporary Mexican architecture, including one of the largest and most impressive thatched-roof "palapas" in the entire country. There are cultural activities, arts and crafts and sports programs to keep you constantly entertained, plus time to relax and enjoy the Mayan culture, soak up the Caribbean sunshine and revel in the international ambiance that settles in after the sun goes down.
Throughout your stay delegates will enjoy a full meal plan, inclusive of beverages. Take your pick from the aromatic Asian delights at Kaumbu, traditional fare at El Mexicano, delicious international cuisine at Kalmia Buffet or perhaps sample the sumptuous Italian dishes at Rosato. There are also several other dining opportunities such as the Cevichería, Pizzeria, Sushi Corner, pool and lounge bar areas. The Gala Night with either a Mayan or Caribbean theme takes place on the third evening of the conference with a mouth-watering feast of local cuisine, an open bar and amazing local entertainment. We welcome all delegates and their accompanying persons to the Gala Night – a truly fun filled night not to be missed!
Hotel Facilities
- Lagoon Pool
- Extensive Health Club and Spa
- Complimentary Wi-Fi in guest rooms and throughout hotel and conference areas
The Fiesta Americana Condesa, Cancun is the 2015 Winner of the Trip Advisor Certificate of Excellence and also received the Travellers Choice Award in 2014.
The remains of ancient Mayan cities are scattered throughout the Yucatan Peninsula and no trip to Cancun would be complete without a visit to these majestic temples and pyramids set amongst lush tropical vegetation. We will be working very closely with a reputable tour company who will be organising trips to Tulum, Chichen Itza, Coba and Xcaret to name a few, some of which may require a full day. Full day excursions will be arranged pre or post conference and may be on an individual or group booking so we would recommend booking extra nights to extend your stay as early as possible to avoid disappointment should these excursions be of interest to you and/or your party. For further information please contact us.
General Information
Venue Rating
★ ★ ★ ★ ★
Currency
US Dollar (USD)
Address
Fiesta Americana Condesa, Blvd.Kukulkán km 16.5 Zona Hotelera, Cancun, 77500 Mexico
Nearest Airport
Cancun International Airport
Location
Cancun is a delightful combination of natural beauty, islands, ecological reserves and white sandy beaches. However, besides sun, sand and sea, this destination also offers an infinite variety of underwater activities to choose from: the diving, snorkelling and fishing here are outstanding and you will find an undersea world packed with tropical fish that live on the second largest barrier reef in the world. Sports enthusiasts might choose one of the many eco-tourism activities, such as cycling or hiking through the tropical forest or kayaking through mangroves, or something a little more adventuresome, like zip lining through the treetops.
Apart from the more well-known ancient Mayan archealogical sites such as Tulum, Cobá and Chichén Itzá you may like to visit the Aktun Chen caverns, voted one of the Top 10 underwater walks by National Geographic described as a truly magical experience.
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