Programme
Wednesday 4th February 2015 |
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12:00 – 15:00 |
Registration |
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13:00 -14:30 |
Welcome Lunch |
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Cancer Session |
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14:45 – 15:00 |
Opening Comments |
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15:00 – 15:35 |
Lynn Heasley |
AUTOCRINE SIGNALING THROUGH NON-MUTATED FGFR1 IN HUMAN CANCERS |
15:35 – 15:55 |
Debbie Cunningham |
CHARACTERISATION OF PHOSPHORYLATION EVENTS DOWNSTREAM OF AMPLIFIED FGFR2 IN THE BREAST CANCER CELL LINES SUM52 AND MFM223 |
15:55 – 16:30 |
Dina Ron |
THE TUMOR SUPPRESSOR, SEF, REGULATES HUMAN EPIDERMIS HOMEOSTASIS THROUGH MULTIPLE MECHANISMS INVOLVING FGF AND PRO-INFLAMMATORY CYTOKINES |
16:30 – 17:00 |
Refreshments |
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17:00 – 17:20 |
Regina Irschick |
MODULATION OF FGFR1 AND FGF2 TRAFFICKING IN HUMAN GLIOMA CELLS |
17:20 – 17:55 |
Fen Wang |
TYPE 2 FIBROBLAST GROWTH FACTOR RECEPTOR SIGNALING IS REQUIRED FOR PRESERVING STEMNESS AND PREVENTING DIFFERENTIATION OF PROSTATE STEM CELLS |
18:00 – 19:30 |
Dinner at Leisure |
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Cancer Session |
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19:30 – 20:05 |
Richard Grose |
MECHANISMS OF FGFR INHIBITOR RESISTANCE IN FGFR-DRIVEN CANCER |
20:05 – 20:25 |
Alvaro Ingles-Prieto |
LIGHT-CONTROLLED RTKS PERMIT CELL-BASED SCREEN OF SMALL MOLECULES |
20:25 |
Poster Viewing |
Thursday 5th February 2015 |
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07:00 -08:30 |
Breakfast |
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Brain Session |
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08:30 – 09:05 |
Ivor Mason |
FGF REGULATION OF CONNECTIVITY IN THE DEVELOPING VERTEBRATE BRAIN |
09:05 -09:40 |
Lars Klimaschewski |
NOVEL APPROACHES TO SPEED UP LONG-DISTANCE AXON REGENERATION BY ENHANCED FGFR1 SIGNALLING |
09:40 – 10:15 |
Mohammad Hajihosseini |
FGF10 FUNCTION IN THE ADULT BRAIN – FROM NEURAL STEM CELLS TO THE CONTROL OF APPETITE/ ENERGY BALANCE |
10:15 – 10:45 |
Refreshments |
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Brain Session |
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10:45 – 11:20 |
Rajesh Ladher |
FGFR1 ROUTES PROTOCADHERIN-15 TO THE CILIUM OF THE INNER EAR HAIR CELLS |
11:20 – 11:55 |
Suzanne Mansour |
FGF SIGNALING IN INNER EAR DEVELOPMENT: HEARING LOST AND FOUND |
12:00 – 15:30 |
Lunch at Leisure & Free Time |
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Regeneration and Disease Session |
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15:30 – 16:05 |
Sabine Werner |
ROLES AND MECHANISMS OF ACTION OF FGFS IN SKIN HOMEOSTASIS AND DISEASE |
16:05 – 16:40 |
Saverio Bellusci |
A BREATH OF FRESH AIR ON THE LUNG MESENCHYME DURING DEVELOPMENT AND DISEASE: LESSONS LEARNT FROM THE FGF AND WNT SIGNALLING |
16:40 – 17:15 |
Xiaokun Li |
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17:15 – 17:50 |
Anne-Karina Perl |
INTERSTITIAL RESIDENT FIBROBLASTS UNDERGO FUNCTIONAL CHANGES DURING ALVEOLAR REGENERATION |
18:00 – 19:30 |
Dinner at Leisure |
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Regeneration and Disease Session |
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19:30 – 20:05 |
David Warburton |
FGF SIGNALING: PUSH ME PULL YOU? |
20:05 – 20:25 |
Robert Guzy |
FIBROBLAST-SPECIFIC FGF SIGNALING IN BLEOMYCIN-INDUCED PULMONARY FIBROSIS |
20:25 – 20:45 |
Chiko Shimbori |
FIBROBLAST GROWTH FACTOR-1 ATTENUATES TGF-β1-INDUCED LUNG FIBROSIS BY REGULATING TGF-β1 SIGNALING |
20:45 |
Poster Viewing |
Friday 6th February 2015 |
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07:00 – 08:30 |
Breakfast |
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Regeneration and Disease Session |
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08:30 – 08:50 |
Stacey House |
CARDIOMYOCYTE-SPECIFIC FIBROBLAST GROWTH FACTOR RECEPTOR SIGNALING PROVIDES ACUTE CARDIOPROTECTION IN A CLOSED-CHEST MODEL OF ACUTE MYOCARDIAL INFARCTION |
08:50 – 09:10 |
Jo El Schultz |
DIFFERENTIAL CARDIOVASCULAR FUNCTIONS OF FIBROBLAST GROWTH FACTOR-2 PROTEIN ISOFORMS IN ISCHEMIA |
09:10 – 09:30 |
Yoshikazu Takada |
FGF-INTEGRIN CROSSTALK THROUGH DIRECT INTEGRIN BINDING TO FGF: DEVELOPMENT OF A DOMINANT-NEGATIVE FGF MUTANT (FGF DECOY) |
09:30 – 09:50 |
Chao Jiang |
DEVELOPMENT OF OLIOSEN-FGF FUSIONS FOR TOPICAL APPLICATIONS |
09:50 – 10:20 |
Refreshments |
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Development Session |
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10:20 – 10:55 |
Matthew Hoffman |
FGF-DEPENDENT WNT SIGNALS REGULATE EPITHELIAL PROGENITOR-NEURONAL INTERACTIONS DURING DEVELOPMENT |
10:55 – 11:30 |
Helen Makarenkova |
FGF SIGNALING IN LACRIMAL GLAND DEVELOPMENT, HOMEOSTASIS AND DISEASE |
11:30 – 11:50 |
Vincent Harley |
CRANIOSYNOSTOSIS WITH XY SEX REVERSAL |
11:50 – 17:30 |
Lunch at Leisure & Free Time |
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Development Session |
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17:30 – 17:50 |
Ing-Ming Chiu |
EXPRESSION PATTERN OF REPORTER GENES DRIVEN BY HUMAN FGF1 PROMOTER IN TRANSGENIC MICE |
17:50 – 18:25 |
Philippe Soriano |
FGF SIGNALING PATHWAYS IN DEVELOPMENT |
18:25 – 18:45 |
Denise Al Alam |
FGF10 IN SMALL INTESTINAL HOMEOSTASIS AND REPAIR |
18:45 – 20:00 |
Poster Session & Cocktails |
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20:15- 23:00 |
Gala Night, Group Photo & Poster Awards |
Saturday 7th February 2015 |
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07:00 -08:30 |
Breakfast |
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Joint session with the Fusion conference on Musculoskeletal Development and Regeneration |
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08:30 – 09:05 |
Lin Chen |
DELETION OF FGFR3 IN CARTILAGE LEADS TO CHONDROMA-LIKE LESION |
09:05 - 09:45 |
Vicki Rosen |
DEVELOPMENTAL REGULATION OF BONE WIDTH BY BMP SIGNALING IS KEY FOR CREATING STRONG BONES |
09:45 – 10:25 |
Maurizio Pacifici |
DEVELOPMENTAL INSIGHTS INTO THE PATHOGENESIS OF HEREDITARY MULTIPLE EXOSTOSES |
10:25 – 10:40 |
Refreshments |
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10:40 – 11:10 |
Veronique Lefebvre |
GENOME-WIDE COOPERATIVITY BETWEEN SOX5/6 AND SOX9 DRIVES CHONDROGENESIS |
11:10 – 11:45 |
David Ornitz |
REGULATION OF SKELETAL GROWTH AND CHONDROGENESIS BY FGFR1 AND FGFR2 SIGNALING IN THE OSTEOPROGENITOR LINEAGE |
11:45 – 12:05 |
Peter Hurlin |
MUTANT ACTIVATED FGFR3 IMPAIRS ENDOCHONDRAL BONE GROWTH BY PREVENTING SOX9 DOWNREGULATION IN DIFFERENTIATING CHONDROCYTES |
12:05 – 12:40 |
Laurence Legeai-Mallet |
FROM FUNCTIONAL STUDIES TO THERAPEUTIC APPROACHES FOR FGFR3-RELATED DISORDERS |
12:40 – 12:50 |
Closing Remarks |