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Neurogenesis Conference
Implications for Lifelong Development and Disease
02 Mar - 05 Mar 2016
Cancun, Mexico
Early Bird - Expired • Talk Submission - Expired • Poster Submission - Expired • Registration & Payment Deadline - Expired
Report
Synopsis
Neural development is not restricted to embryonic or early postnatal stages but continuous throughout life in the mammalian brain. This conference will bring together leaders from diverse fields such as embryonic cortical development, adult neurogenesis, human imaging, and stem cell-based neural disease modelling to discuss recent advances in understanding the cellular and molecular mechanisms regulating neural stem cell activity, neuronal specification and functional significance of circuitries modified by the addition of new neurons. In addition, translational perspectives and implications for disease modelling will be covered.
Target Audience
Junior (i.e., PhD students and postdocs) and senior scientists (i.e., group leaders and professors) and physician-scientists in academia, biotech and pharmaceutical companies who would like to gain a better understanding in mechanisms underlying the neurogenic process in the developing and adult brain in physiology and disease. Further, the audience will be interested to engage in discussions on state of the art in each of these areas. The confirmed list of speakers with the majority of academic and pharmaceutical industry leaders in the respective fields present will make this conference the major event in the field for 2016.
Plenary Speakers
Dr. Onur Basak (Hubrecht Institute)
HOW NICHE SIZE CONTROLS ADULT NEURAL STEM CELL NUMBER AND LONGEVITY
Prof. Gordon Fishell (NYU Langone Medical Center)
NON-CANONICAL WNT-SIGNALING REGULATES THE RATIO OF SOMATOSTATIN- AND PARVALBUMIN- EXPRESSING CORTICAL INTERNEURONS
Prof. Fred H. Gage (Salk Institute)
HOW CAN A NEW NEURON INTEGRATE IN AN ADULT BRAIN?
Prof. Dr. Magdalena Götz (Institute of Stem Cell Research, Helmholtz Center Munich)
THE EMBO KEYNOTE LECTURE
Prof. Rene Hen (Columbia University)
IMAGING AND MANIPULATING YOUNG GRANULE CELLS: IMPLICATIONS FOR MOOD AND COGNITIVE DISORDERS
Prof. Rudolf Jaenisch (Whitehead Institute)
IPS CELL TECHNOLOGY AND DISEASE RESEARCH
Prof. Dr. Sebastian Jessberger (University of Zurich)
Prof. Dr. Gerd Kempermann (CRTD Dresden)
ADULT NEUROGENESIS: AN INDIVIDUALIZING EXPERIENCE
Prof. Pierre-Marie Lledo (Institut Pasteur)
WHEN CORTICAL AFFERENTS NEED ADULT-BORN NEURONS TO INFLUENCE OLFACTION
Prof. Guo-li Ming (Johns Hopkins University)
DISSECTING THE INTEGRATION PROCESS OF ADULT GENERATED NEURONS
Prof. Alejandro Schinder (Fundación Instituto Leloir)
REMODELING DENTATE GYRUS ARCHITECTURE AND FUNCTION BY NEW GRANULE CELLS
Prof. Hongjun Song (Johns Hopkins University)
Invited Speakers
Prof. Dr. Benedikt Berninger (Universitätsmedizin Mainz)
MOLECULAR AND CELLULAR CONSTRAINTS OF TRANSCRIPTION FACTOR- INDUCED NEUROGENIC REPROGRAMMING
Prof. Michael Bonaguidi (University of Southern California)
DIVERSITY AND PLASTICITY OF ADULT HIPPOCAMPAL NEURAL STEM CELLS
Prof. Dr. Dieter Chichung Lie (Friedrich-Alexander University Erlangen-Nuremberg)
TRANSCRIPTIONAL REGULATION OF FUNCTIONAL MATURATION IN ADULT NEUROGENESIS
Prof. Amelia J. Eisch (UT Southwestern Medical Center)
STIMULATION OF ENTORHINAL CORTEX-DENTATE GYRUS CIRCUITRY IS ANTIDEPRESSIVE
Prof. Paul Frankland (Hospital for Sick Children)
MECHANISMS OF NEUROGENESIS-MEDIATED FORGETTING OF HIPPOCAMPAL MEMORIES
Prof. Shaoyu Ge (Stony Brook University)
INITIATION OF CIRCUIT INTEGRATION AND UNDERLYING MECHANISMS OF ADULT-BORN NEURONS
Prof. Yukiko Gotoh (University of Tokyo)
REGULATION OF NEURAL STEM CELL FATE DURING EMBRYOGENESIS AND IN THE ADULT
Prof. Jenny Hsieh (UT Southwestern Medical Center)
TRANSCRIPTIONAL REGULATION OF ADULT NEUROGENESIS IN NORMAL AND EPILEPTIC BRAIN
Dr. Ravi Jagasia (Roche)
HUMAN NEUROGENESIS SCREENING AND BIOMARKER IDENTIFICATION USING EMBRYONIC DERIVED NEURONAL PRECURSORS
Prof. Mi-hyeon Jang (Mayo Clinic)
BUBR1 INSUFFICIENCY IMPAIRS ADULT HIPPOCAMPAL NEUROGENESIS AND COGNITIVE FUNCTION
Prof. Mirjana Maletić-Savatić (Baylor College of Medicine)
MEASURING NEUROGENESIS IN THE LIVE HUMAN BRAIN
Prof. Dr. Ana Martin-Villalba (DKFZ)
STEM CELL HETEROGENEITY IN HOMEOSTASIS AND DISEASE
Prof. Alysson R. Muotri (University of California, San Diego)
LINE-1 RETROTRANSPOSITION IN THE BRAIN AND NEUROLOGICAL DISORDERS
Prof. Kinichi Nakashima (Kyushu University)
TLR9 SIGNALING IN MICROGLIA ENSURES HOMEOSTATIC NEUROGENESIS IN THE ADULT HIPPOCAMPUS
Prof. Jack Parent (University of Michigan Medical School)
STRUCTURAL AND FUNCTIONAL CHANGES OF BIRTHDATED DENTATE GRANULE CELLS IN EXPERIMENTAL TEMPORAL LOBE EPILEPSY
Dr. Sergiu Pasca (Stanford University)
DEVELOPING IN VITRO HUMAN MODELS FOR NEURODEVELOPMENTAL DISORDERS
Prof. Amar Sahay (Harvard University)
REJUVENATING AND RE-ENGINEERING AGING MEMORY CIRCUITS
Prof. Juan Song (UNC School of Medicine)
LOCAL CHOLECYSTOKININ-EXPRESSING INTERNEURON CIRCUIT REGULATES QUIESCENT NEURAL STEM CELLS IN THE ADULT HIPPOCAMPUS
Prof. Verdon Taylor (University of Basel)
REGULATION OF OLIGODENDROCYTE DIFFERENTIATION IN THE HIPPOCAMPAL NEUROGENIC NICHE
Prof. Nicolas Toni (University of Lausanne)
FINE STRUCTURE OF RADILA GLIA-LIKE NEURAL STEM CELLS IN THE ADULT HIPPOCAMPUS
Prof. Pierre Vanderhaeghen (University of Brussels)
FROM PLURIPOTENT STEM CELLS TO CORTICAL CIRCUITS
Prof. Chun-Li Zhang (UT Southwestern Medical Center)
IN VIVO REPROGRAMMING FOR INDUCED ADULT NEUROGENESIS
Prof. Su- Chun Zhang (University of Wisconsin)
REGULATION OF HUMAN NEURAL CIRCUITS
Prof. Xinyu Zhao (University of Wisconsi-Madison)
DISSECTING NEUROGENIC IMPAIRMENT IN NEURODEVELOPMENTAL DISORDERS
Confirmed Speakers
Chairs
Plenary Speakers
Rudolf Jaenisch
Member, WIBR and Professor of Biology, M.I.T., Whitehead Institute for Biomedical Research
Fred Gage
Adler Chair on Age Related Diseases, Salk Institute for Biological Studies
Gordon Fishell
Associate Director, NYU Neuroscience Institute
Alejandro Schinder
Principal Investigator, Instituto Leloir
Gerd Kempermann
Professor, German Center for Neurodegenerative Diseases (DZNE) Dresden
Rene Hen
Professor, Columbia University
Magdalena Götz
Director, Helmholtz Zentrum München & LMU
Onur Basak
Researcher, Hubrecht Institute
Pierre-Marie Lledo
Chairman of the Neuroscience Department, The Pasteur Institute
Invited Speakers
Yukiko Gotoh
Professor, The University of Tokyo
Paul Frankland
Senior Scientist, Hospital for Sick Children
Nicolas Toni
Professor, University of Lausanne
Alysson Muotri
Professor, University of California San Diego
Kinichi Nakashima
Professor, Graduate School of Medical Sciences, Kyushu University
Jack Parent
Professor of Neurology, University of Michigan
Verdon Taylor
Group Leader, University of Basel
Amar Sahay
Associate Professor, MGH and Harvard Medical School
Xinyu Zhao
Professor, University of Wisconsin-Madison
Chichung Lie
Professor, FAU Erlangen-Nürnberg
Shaoyu Ge
Associate Professor, SUNY Stony Brook
Chun-Li Zhang
Associate Professor, UT Southwestern Medical Center
Michael Bonaguidi
Assistant Professor, USC
Jenny Hsieh
Professor, The University of Texas at San Antonio
Su-Chun Zhang
Professor, University of Wisconsin
Ana Martin-Villalba
Professor and Division Head, German Cancer Research Center (DKFZ)
Pierre Vanderhaeghen
Professor, ULB
Silvia Cappello
Research Group Leader, Max Planck Institute of Psychiatry
Mirjana Maletic-Savatic
Assistant Professor, Baylor College of Medicine
Sergiu Pasca
Professor, Stanford University
Benedikt Berninger
Professor, King's College London
Amelia Eisch
Professor , Perelman School of Medicine University of Pennsylvania, CHOP
Juan Song
Professor, Jeffrey Houpt Distinguished Investigator, University of North Carolina, Chapel Hill
Ravi Jagasia
Lab Head, F. Hoffmann-La Roche, Pharma Research and Early Development
Programme
Wednesday 2nd March 2016 |
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14:00 – 14:40 |
Registration |
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14:00 – 14:40 |
Welcome Lunch |
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14:40 – 14:55 |
Opening Comments |
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14:55 – 15:30 |
Magdalena Götz |
THE EMBO KEYNOTE LECTURE |
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MECHANISMS OF NEUROGENESIS I |
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15:30 – 16:00 |
Sebastian Jessberger |
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16:00 – 16:15 |
Grigori Enikolopov |
SIGNALING LANDSCAPE OF NEURAL STEM CELLS AND THEIR NICHE |
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16:15 – 16:45 |
Xinyu Zhao |
DISSECTING NEUROGENIC IMPAIRMENT IN NEURODEVELOPMENTAL DISORDERS |
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16:45 – 17:15 |
Refreshments |
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17:15 – 17:45 |
Michael Bonaguidi |
DIVERSITY AND PLASTICITY OF ADULT HIPPOCAMPAL NEURAL STEM CELLS |
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17:45 – 18:15 |
Pierre-Marie LLedo |
WHEN CORTICAL AFFERENTS NEED ADULT-BORN NEURONS TO INFLUENCE OLFACTION |
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18:15 – 18:30 |
Armen Saghatelyan |
PRINCIPAL CELL ACTIVITY INDUCES SPINE RELOCATION OF ADULT-BORN INTERNEURONS IN THE OLFACTORY BULB |
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18:30 – 19:30 |
Poster Session I |
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19:30 |
Dinner at Leisure & Free Time |
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Thursday 3rd March 2016 |
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07:00 – 08:00 |
Breakfast |
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MECHANISMS OF NEUROGENESIS II |
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08:00 – 08:30 |
Hongjun Song |
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08:30 – 09:00 |
Kinichi Nakashima |
TLR9 SIGNALING IN MICROGLIA ENSURES HOMEOSTATIC NEUROGENESIS IN THE ADULT HIPPOCAMPUS |
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09:00 – 09:30 |
Jenny Hsieh |
TRANSCRIPTIONAL REGULATION OF ADULT NEUROGENESIS IN NORMAL AND EPILEPTIC BRAIN |
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09:30 – 10:00 |
Dieter Chichung Lie Friedrich-Alexander University Erlangen-Nuremberg |
TRANSCRIPTIONAL REGULATION OF FUNCTIONAL MATURATION IN ADULT NEUROGENESIS |
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10:00 – 10:30 |
Refreshments & Group Photo |
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MECHANISMS OF NEUROGENESIS III |
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10:30 – 11:00 |
Fred H. Gage |
HOW CAN A NEW NEURON INTEGRATE IN AN ADULT BRAIN? |
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11:00 – 11:30 |
Verdon Taylor |
REGULATION OF OLIGODENDROCYTE DIFFERENTIATION IN THE HIPPOCAMPAL NEUROGENIC NICHE |
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11:30 – 12:00 |
Shaoyu Ge |
INITIATION OF CIRCUIT INTEGRATION AND UNDERLYING MECHANISMS OF ADULT-BORN NEURONS |
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12:00 – 12:30 |
Amelia Eisch |
STIMULATION OF ENTORHINAL CORTEX-DENTATE GYRUS CIRCUITRY IS ANTIDEPRESSIVE |
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12:30 – 12:45 |
Marlen Knobloch |
THE RATE OF FATTY ACID OXIDATION REGULATES QUIESCENCE IN ADULT NEURAL STEM CELLS |
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12:45 – 13:00 |
Ruth Beckervordersandforth |
MITOCHONDRIAL METABOLISM CONTROLS EARLY LINEAGE PROGRESSION AND AGEING PHENOTYPES IN ADULT HIPPOCAMPAL NEUROGENESIS |
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13:00 – 16:00 |
Lunch at Leisure & Free Time |
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NETWORK REGULATION |
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16:00 – 16:30 |
Alejandro Schinder |
REMODELING DENTATE GYRUS ARCHITECTURE AND FUNCTION BY NEW GRANULE CELLS |
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16:30 – 17:00 |
Juan Song |
LOCAL CHOLECYSTOKININ-EXPRESSING INTERNEURON CIRCUIT REGULATES QUIESCENT NEURAL STEM CELLS IN THE ADULT HIPPOCAMPUS |
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17:00 – 17:30 |
Nicolas Toni |
FINE STRUCTURE OF RADILA GLIA-LIKE NEURAL STEM CELLS IN THE ADULT HIPPOCAMPUS |
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17:30 – 17:45 |
Heather Cameron |
STRESS, AMBIGUITY, AND THE ROLE OF ADULT NEUROGENESIS IN RESPONSE TO THREAT |
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17:45 – 18:15 |
Refreshments |
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CELLULAR IDENTITY |
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18:15 – 18:45 |
Gordon Fishell |
NON-CANONICAL WNT-SIGNALING REGULATES THE RATIO OF SOMATOSTATIN- AND PARVALBUMIN- EXPRESSING CORTICAL INTERNEURONS |
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18:45 – 19:15 |
Yukiko Gotoh |
REGULATION OF NEURAL STEM CELL FATE DURING EMBRYOGENESIS AND IN THE ADULT |
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19:15 – 19:30 |
Orly Lazarov |
MECHANISM AND FUNCTIONAL SIGNIFICANCE OF NEUROGENESIS: INSIGHT FROM COGNITIVE DYSFUNCTION |
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19:30 – 19:45 |
Alexey Terskikh |
DISTINCT EPIGENETIC FUNCTIONS OF SOX2 IN SELF-RENEWAL AND DIFFERENTIATION |
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19:45 |
Dinner at Leisure & Free Time |
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Friday 4th March 2016 |
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07:00 – 08:00 |
Breakfast |
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FUNCTIONAL SIGNIFICANCE OF NEUROGENESIS |
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08:00 – 08:30 |
Gerd Kempermann |
ADULT NEUROGENESIS: AN INDIVIDUALIZING EXPERIENCE |
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08:30 – 09:00 |
Paul Frankland |
MECHANISMS OF NEUROGENESIS-MEDIATED FORGETTING OF HIPPOCAMPAL MEMORIES |
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09:00 – 09:30 |
Amar Sahay |
REJUVENATING AND RE-ENGINEERING AGING MEMORY CIRCUITS |
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09:30 – 10:00 |
Refreshments |
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TARGETING NEUROGENESIS |
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10:00 – 10:30 |
Rene Hen |
IMAGING AND MANIPULATING YOUNG GRANULE CELLS: IMPLICATIONS FOR MOOD AND COGNITIVE DISORDERS |
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10:30 – 11:00 |
Jack Parent |
STRUCTURAL AND FUNCTIONAL CHANGES OF BIRTHDATED DENTATE GRANULE CELLS IN EXPERIMENTAL TEMPORAL LOBE EPILEPSY |
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11:00 – 11:30 |
Ravi Jagasia |
HUMAN NEUROGENESIS SCREENING AND BIOMARKER IDENTIFICATION USING EMBRYONIC DERIVED NEURONAL PRECURSORS |
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11:30 – 12:00 |
Ana Martin-Villalba |
STEM CELL HETEROGENEITY IN HOMEOSTASIS AND DISEASE |
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12:00 – 17:00 |
Lunch at Leisure & Free Time |
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DETECTION OF NEUROGENESIS |
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17:00 – 17:30 |
Onur Basak |
HOW NICHE SIZE CONTROLS ADULT NEURAL STEM CELL NUMBER AND LONGEVITY |
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17:30 – 18:00 |
Mirjana Maletic-Savatic |
MEASURING NEUROGENESIS IN THE LIVE HUMAN BRAIN |
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MANIPULATING STEM CELL PROPERTIES |
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18:00 – 18:30 |
Chun-Li Zhang |
IN VIVO REPROGRAMMING FOR INDUCED ADULT NEUROGENESIS |
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18:30 – 19:00 |
Rudolf Jaenisch |
IPS CELL TECHNOLOGY AND DISEASE RESEARCH |
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19:00 – 20:00 |
Poster Session II, Cocktails & Refreshments |
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20:15 – 23:00 |
Gala Night & Poster Awards |
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Saturday 5th March 2016 |
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07:00 – 08:00 |
Breakfast |
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NEUROGENESIS IN THE DISH |
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08:00 – 08:30 |
Guo-Li Ming |
DISSECTING THE INTEGRATION PROCESS OF ADULT GENERATED NEURONS |
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08:30 – 09:00 |
Pierre Vanderhaeghen |
FROM PLURIPOTENT STEM CELLS TO CORTICAL CIRCUITS |
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09:00 – 09:30 |
Su- Chun Zhang |
REGULATION OF HUMAN NEURAL CIRCUITS |
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09:30 – 09:45 |
Matteo Bergami |
DIRECTED GENERATION OF CORTICAL-LIKE NEURONS IN THE ADULT HIPPOCAMPUS |
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09:45 – 10:00 |
Darcie Moore |
THE PRESENCE AND FUNCTION OF A DIFFUSION BARRIER IN MAMMALIAN NEURAL STEM CELLS AS A MECHANISM TO SEGREGATE AGE |
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10:00 – 10:30 |
Refreshments |
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DISEASE MODELING |
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10:30 – 11:00 |
Benedikt Berninger |
MOLECULAR AND CELLULAR CONSTRAINTS OF TRANSCRIPTION FACTOR- INDUCED NEUROGENIC REPROGRAMMING |
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11:00 – 11:30 |
Alysson Muotri |
LINE-1 RETROTRANSPOSITION IN THE BRAIN AND NEUROLOGICAL DISORDERS |
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11:30 – 11:45 |
Silvia Cappello |
MODELING PERIVENTRICULAR HETEROTOPIA IN HUMAN ORGANOIDS WITH MUTATIONS IN FAT4 AND DCHS1 |
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11:45 – 12:15 |
Sergiu Pasca |
DEVELOPING IN VITRO HUMAN MODELS FOR NEURODEVELOPMENTAL DISORDERS |
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12:15 – 12:30 |
Closing Remarks |
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Sunday 6th March 2016 |
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08:15 - 17:30 |
Chichen-Itzá Group Tour |
Supported by
Venue & Location
Fiesta Americana Condesa
This stylish hotel features contemporary Mexican architecture, including one of the largest and most impressive thatched-roof "palapas" in the entire country. There are cultural activities, arts and crafts and sports programs to keep you constantly entertained, plus time to relax and enjoy the Mayan culture, soak up the Caribbean sunshine and revel in the international ambiance that settles in after the sun goes down.
Throughout your stay delegates will enjoy a full meal plan, inclusive of beverages. Take your pick from the aromatic Asian delights at Kaumbu, traditional fare at El Mexicano, delicious international cuisine at Kalmia Buffet or perhaps sample the sumptuous Italian dishes at Rosato. There are also several other dining opportunities such as the Cevichería, Pizzeria, Sushi Corner, pool and lounge bar areas. The Gala Night with either a Mayan or Caribbean theme takes place on the third evening of the conference with a mouth-watering feast of local cuisine, an open bar and amazing local entertainment. We welcome all delegates and their accompanying persons to the Gala Night – a truly fun filled night not to be missed!
Hotel Facilities
- Lagoon Pool
- Extensive Health Club and Spa
- Complimentary Wi-Fi in guest rooms and throughout hotel and conference areas
The Fiesta Americana Condesa, Cancun is the 2015 Winner of the Trip Advisor Certificate of Excellence and also received the Travellers Choice Award in 2014.
The remains of ancient Mayan cities are scattered throughout the Yucatan Peninsula and no trip to Cancun would be complete without a visit to these majestic temples and pyramids set amongst lush tropical vegetation. We will be working very closely with a reputable tour company who will be organising trips to Tulum, Chichen Itza, Coba and Xcaret to name a few, some of which may require a full day. Full day excursions will be arranged pre or post conference and may be on an individual or group booking so we would recommend booking extra nights to extend your stay as early as possible to avoid disappointment should these excursions be of interest to you and/or your party. For further information please contact us.
General Information
Venue Rating
★ ★ ★ ★ ★
Currency
US Dollar (USD)
Address
Fiesta Americana Condesa, Blvd.Kukulkán km 16.5 Zona Hotelera, Cancun, 77500 Mexico
Nearest Airport
Cancun International Airport
Location
Cancun is a delightful combination of natural beauty, islands, ecological reserves and white sandy beaches. However, besides sun, sand and sea, this destination also offers an infinite variety of underwater activities to choose from: the diving, snorkelling and fishing here are outstanding and you will find an undersea world packed with tropical fish that live on the second largest barrier reef in the world. Sports enthusiasts might choose one of the many eco-tourism activities, such as cycling or hiking through the tropical forest or kayaking through mangroves, or something a little more adventuresome, like zip lining through the treetops.
Apart from the more well-known ancient Mayan archealogical sites such as Tulum, Cobá and Chichén Itzá you may like to visit the Aktun Chen caverns, voted one of the Top 10 underwater walks by National Geographic described as a truly magical experience.
Gallery
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Conference Manager
Jack Peters
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