Programme
FRIDAY 28TH FEBRUARY |
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13:00 – 14:00 |
Student Networking Lunch |
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15:00 – 16:00 |
Registration & Welcome Reception |
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Chromatin Complexes in Development and Diseases |
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16:00 – 16:10 |
Opening Comments |
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16:10 – 16:35 |
Luciano Di Croce |
MOLECULAR MECHANISMS GOVERNING CELL IDENTITY, DIFFERENTIATION AND CANCER PROCESSES |
16:35 – 17:00 |
Adrian Bracken |
PRC2 COMPLEXES IN DEVELOPMENT AND DISEASE |
17:00 – 17:25 |
Robert Kingston |
NUCLEOSOME COMPACTION, PHASE SEPARATION, AND POLYCOMB-GROUP MAINTENANCE OF REPRESSION |
17:25 – 17:40 |
Chen Davidovich |
MECHANISM FOR THE REGULATION OF PRC2 BY PALI1 |
17:40 – 18:25 |
Refreshments |
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18:25 – 18:40 |
Uhnsoo Cho |
CRYO-EM STRUCTURE OF THE HUMAN MIXED LINEAGE LEUKEMIA-1 COMPLEX BOUND TO THE NUCLEOSOME |
18:40 – 18:55 |
Alea Mills |
EPIGENETIC VULNERABILITIES OF HUMAN GLIOBLASTOMA |
18:55 – 19:10 |
Shigeki Iwase |
AMELIORATION OF BRAIN HISTONE METHYLOPATHIES BY BALANCING A WRITER-ERASER DUO KMT2A-KDM5C |
19:10 – 19:30 |
Esther Schnapp |
REVIEW COMMONS AND PUBLISHING WITH EMBO PRESS |
19:30 – 20:00 |
Meet the Poster Presenters |
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20:00 |
Group Dinner |
SATURDAY 29TH FEBRUARY |
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07:00 – 08:55 |
Breakfast at Leisure |
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Mechanistic Insight into Multi-Protein Chromatin Complexes Regulation |
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08.55 – 09:10 |
Alfredo Valencia |
RECURRENT C-TERMINAL SMARCB1 MUTATIONS REVEAL A NUCLEOSOME ACIDIC PATCH INTERACTION THAT POTENTIATES mSWI/SNF CHROMATIN REMODELING |
09:10 – 09:35 |
Ali Shilatifard |
PRINCIPLES OF EPIGENETICS AND CHROMATIN IN DEVELOPMENT AND HUMAN DISEASE |
09:35 – 10:00 |
Amanda Fisher |
EPIGENETICS AND INHERITANCE |
10:00 – 10:25 |
Karen Adelman |
CONTROLLING TRANSCRIPTION AT CODING AND NON-CODING RNA LOCI |
10:25 – 12:15 |
Poster Session |
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12:15 – 16:55 |
Lunch at Leisure & Free Time |
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From Gene Regulation to Chromatin Architecture |
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16:55 – 17:20 |
Rab Prinjha |
DRUGGING TRANSCRIPTION: PROGRESS AND POTENTIAL FOR TREATING HUMAN DISEASES |
17:20 – 17:45 |
Giacomo Cavalli |
3D GENOME ORGANIZATION AND POLYCOMB PROTEINS IN DEVELOPMENT AND CELL DIFFERENTIATION |
17:45 – 18:00 |
Meelad Dawlaty |
NON-ENZYMATIC FUNCTIONS OF TET1 REGULATE BIVALENCY AT LINEAGE SPECIFIC GENES IN EMBRYONIC STEM CELLS TO ENSURE PROPER DIFFERENTIATION AND DEVELOPMENT |
18:00 – 18:45 |
Refreshments & Poster Viewing |
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Ting (C.-ting) Wu |
SUCH A LOT OF GENOME TO SEE… |
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Victor Corces |
MECHANISMS OF TRANSGENERATIONAL INHERITANCE OF OBESITY EPIPHENOTYPES |
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19:35 – 20:00 |
Anthony Schmitt |
DISCOVERY OF GENOMIC INTERACTIONS AND GENE REGULATORY MECHANISMS USING THE ARIMA-HIC PLATFORM |
20:00 |
Group Dinner |
SUNDAY 1ST MARCH |
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07:00 – 08:30 |
Breakfast at Leisure |
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Chromatin Alterations in Human Diseases |
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08:30 – 08:55 |
Salvador Aznar Benitah |
IMPACT OF HETEROCHROMATIN REGULATION IN ADULT STEM CELL FUNCTION AND MUTATIONAL BURDEN IN CANCER STEM CELLS |
08:55 – 09:20 |
Irene Chiolo |
WHEN SILENCE IS LOUD: HETEROCHROMATIN REPAIR MECHANISMS FOR GENOME STABILITY |
09:20 – 09:35 |
Nicole Vander Schaaf |
THE DNA METHYLATION LANDSCAPE OF INTESTINAL CELLS INFLUENCES THE TUMORIGENICITY OF A GENETIC DRIVER MUTATION |
09:35 – 10:00 |
Yad Ghavi-Helm |
REGULATING GENE EXPRESSION IN 3D DURING EMBRYONIC DEVELOPMENT |
10:00 – 10:45 |
Group Photo, Refreshments & Poster Viewing |
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10:45 – 11:00 |
Sundeep Kalantry |
KDM5C AND THE EVOLUTIONARY ORIGINS OF X-CHROMOSOME INACTIVATION |
11:00 – 11:25 |
Tony Kouzarides |
MODIFICATIONS OF RNA AND THEIR ROLE IN CANCER |
Yael David |
NON-ENZYMATIC MODIFICATIONS ON HISTONES DRIVE CHANGES IN CHROMATIN STRUCTURE AND FUNCTION |
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11:50 – 12:15 |
Jeannie Lee |
THE MANY FACES OF XIST RNA IN 3D |
12:15 – 16:45 |
Lunch at Leisure & Free Time |
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RNA and Chromatin Organization |
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16:45 – 17:10 |
Geeta Narlikar |
CAN PHASE-SEPARATION EXPLAIN HETEROCHROMATIN PROPERTIES? |
17:10 – 17:25 |
Jane Skok |
CTCFL AND ITS IMPACT ON GENE REGULATION AND INTERPLAY WITH CTCF FUNCTION |
17:25 – 17:50 |
Ramin Shiekhattar |
REGULATION OF THE CODING AND NONCODING GENOME BY INTEGRATOR |
17:50 – 18:05 |
Marissa Cloutier |
MATERNAL CONTROL OF PATERNAL X-INACTIVATION |
18:05 – 18:50 |
Refreshments & Poster Viewing |
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18:50 – 19:15 |
Roberto Bonasio |
REGULATION OF CHROMATIN COMPLEXES BY RNA |
19:15 – 19:40 |
François Fuks |
TRANSCRIPTOME-WIDE DISTRIBUTION AND FUNCTION OF RNA MODIFICATIONS |
19:40 – 19:55 |
Elizabeth Kahney |
INVESTIGATING HISTONE INHERITANCE PATTERNS AT SPECIFIC GENOMIC LOCI |
20:00 |
Gala Dinner & Poster Awards |
MONDAY 2ND MARCH |
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07:00 – 09:00 |
Breakfast at Leisure |
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Neuroepigenetics |
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09:00 – 09:25 |
Hans van Bokhoven |
IMPACT: IDENTIFICATION OF CONVERGING MOLECULAR PATHWAYS ACROSS CHROMATINOPATHIES AS TARGETS FOR THERAPY |
09:25 – 09:40 |
Gaia Novarino |
EPIGENETIC DEFECTS IN NEURODEVELOPMENTAL DISORDERS |
09:40 – 09:55 |
Michele Gabriele |
ONE BY ONE: CONVERGENCE, MULTIPLEXING AND SINGLE-CELL RESOLUTION IN THE STUDY OF NEURODEVELOPMENTAL DISORDERS THROUGH BRAIN ORGANOIDS |
09:55 – 10:10 |
Refreshments |
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10:10 – 10:25 |
Frank Kooy |
ON A COMPLEX NEURODEVELOPMENTAL DISORDER COUSED BY MUTATIONS IN ADNP IN MAN AND MOUSE |
10:25 – 10:40 |
James Ellis |
ALTERED TRANSLATION AND PROTEIN STABILITY DURING NEURODEVELOPMENT AFFECT DRUGGABLE PATHWAYS IN RETT SYNDROME |
10:40 – 10:55 |
Ann Boija |
DIFFERENTIAL PARTITIONING OF CANCER THERAPEUTICS IN NUCLEAR CONDENSATES |
10:55 – 11:00 |
Closing Comments |