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3rd Synthetic Biology of Natural Products Conference
The Interface of (Meta)Genomics, Synthetic Biology and Natural Product Discovery and Development #SBNP22
16 May - 19 May 2022
Cancun, Mexico
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Michael Burkart
University of California, San Diego
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David Mead
Terra Bioworks
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Nigel Mouncey
DOE Joint Genome Institute
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Rebecca Goss
University of St Andrews
Early Bird - Expired • Talk Submission - Expired • Poster Submission - Expired • Registration & Payment Deadline - Expired
Synopsis
Genome sequencing has revealed an enormous untapped biosynthetic capacity for microbial natural products, only a small fraction of which are represented in fermentation-based screens. Synthetic biology tools are being developed to translate the encoded diversity of microbial biosynthetic pathways into novel compounds and natural products. The Synthetic Biology of Natural Products conference will blend these disciplines with the goal of generating new platforms, tools and technologies to capture, manipulate and engineer natural product genes and pathways. Converting this vast untapped (meta)genomic diversity into novel chemical leads for biomedical and agricultural applications will require breakthroughs in design, scale and biologics that currently limit the field.
Key Sessions
- (Meta)Genomics-Enabled Natural Product Discovery
- Synthetic Biology to Access and Optimize Natural Products
- Novel Chemistry and Enzymology of Natural Products and their Analogues
- Bringing Natural Products to the Market
Student Offer
Take advantage of this fantastic opportunity for students! Fully paying academics can bring a student for only $785. Unfortunately, Postdocs are not eligible. Both registration packages include; accommodation for the 16, 17, 18 May 2022 (on a shared basis for students) and a 24hour all-inclusive food and beverage package for the conference period. Once registered, please contact Laura Trundle to obtain a special registration link for your student.
Confirmed Invited Speakers
Constance Bailey (University of Tennessee-Knoxville)
THE INVESTIGATING EFFECTS OF THE FUNCTIONAL CONSEQUENCES OF HETEROLGOUS EXPRESSION ON MEGASYNTHASES FROM ACTINOMYCETES
Cuauhtemoc Licona Cassani (Tecnológico de Monterrey)
BIODIVERSITY AND SPECIALIZED METABOLISM: TALES OF NATURAL PRODUCTS FROM MEXICAN ECOLOGICAL NICHES
Marc Chevrette (University of Wisconsin-Madison)
DYNAMIC SECONDARY METABOLISM IN A MODEL RHIZOSPHERE COMMUNITY
Yousong Ding (University of Florida)
AN INTEGRATED PIPELINE FOR DISCOVERY AND PRODUCTION OF BIOACTIVE MARINE NATURAL PRODUCTS
Alessandra Eustaquio (University of Illinois at Chicago)
DEVELOPMENT OF A BURKHOLDERIA BACTERIAL HOST FOR NATURAL PRODUCT DISCOVERY
Bill Fenical (University of California, San Diego)
VALIDATING THE STEREOSPECIFICITIES OF TYPE 1 PKS MODULAR ENZYMES IN MACROLIDE BIOSYNTHESIS
Adrian Keatinge-Clay (University of Texas at Austin)
ENGINEERING POLYKETIDE SYNTHASES USING THE CORRECT MODULE BOUNDARY
Nancy Keller (University of Wisconsin-Madison)
ECOLOGICALLY RELEVANT SECONDARY METABOLITES IN FUNGAL-BACTERIAL COMMUNICATION
Bill Kinney (IteraMed)
SYNTHETIC AND BIOSYNTHETIC APPROACHES TO A NEW MAMMALIAN AMINOSTEROL (ENT-03) WITH PROFOUND METABOLIC ACTIVITY
Mark Liles (Auburn University)
SOIL MICROORGANISMS AND METAGENOMES AS SOURCES OF ANTI-INFECTIVE METABOLITES
Norberto P. Lopes (University of São Paulo)
THE RATIONAL SEARCH FOR BIOLOGICALLY ACTIVE SUBSTANCES THROUGH MASS SPECTROMETRY
Simon Moore (University of Kent)
A STREPTOMYCES TRANSCRIPTION-TRANSLATION TOOLKIT FOR SYNTHETIC BIOLOGY AND NATURAL PRODUCT APPLICATIONS
Rolf Müller (Helmholtz Centre For Infection Research)
PRECLINICAL OPTIMIZATION OF NATURAL PRODUCTS USING SYNTHETIC BIOLOGY APPROACHES
Julia Nepper (University of Wisconsin-Madison)
A BACILLUS CEREUS ANTIBIOTIC AFFECTS PHYSIOLOGY OF AN ECOLOGICAL NEIGHBOR
Guy Polturak (John Innes Centre)
GENOMICS-DRIVEN DISCOVERY OF CLUSTERED BIOSYNTHETIC PATHWAYS FOR DEFENSE-RELATED MOLECULES IN BREAD WHEAT
Tom Ramseier (LifeMine Therapeutics)
MINING THE PAN-FUNGAL KINGDOM FOR GENETICALLY ENCODED SMALL MOLECULES (GEMs)
Avena Ross (Queen's University)
PROBING BIOSYNTHETIC APPROACHES FOR TAMBJAMINE PRODUCTION
Evi Stegmann (University of Tübingen)
GLYCOPEPTIDE BIOSYNTHESES: LEARNING FROM NATURE´S PARADIGMS FOR SYNTHETIC BIOLOGY
Jackie Winter (University of Utah)
UNLOCKING THE CHEMICAL POTENTIAL OF THE FUNGAL TERPENOME
Alexander Wentzel (SINTEF Industry)
NEW NATURAL PRODUCTS FROM MARINE ACTINOBACTERIA AND MICROBIOMES
Target Audience
Synthetic biology scientists and companies looking to learn the latest engineering and synthetic biology technologies for converting small molecule, natural product pathways into novel compounds. Topics discussed during the conference will span the experimental spectrum from molecular biology, microbiology, drug discovery, chemistry and pharmacology, to antibiosis activities against cancer, viral and microbial pathogens, as well as biocontrol and biostimulants.
Educational Need
A new generation of tools and technologies is needed to convert the vast biodiversity found in natural product pathways into bioactive compounds and treatments. The Synthetic Biology of Natural Products conference will bring together a broad spectrum of research scientists and corporate managers interested in learning about the latest developments in this new field.
Confirmed Speakers
Chairs
Michael Burkart
Professor, University of California, San Diego
David Mead
CEO & Co-founder, Terra Bioworks
Nigel Mouncey
Director, DOE Joint Genome Institute
Rebecca Goss
Professor, University of St Andrews
Invited Speakers
Bill Kinney
Senior VP of R & D, Enterin Inc.
Jaclyn Winter
Assistant Professor, University of Utah
Adrian Keatinge-Clay
Associate Professor, The University of Texas at Austin
Mark Liles
Professor, Auburn University
Constance Bailey
Assistant Professor, University of Tennessee-Knoxville
Tom Ramseier
VP, Synthetic Biology, LifeMine Therapeutics
Evi Stegmann
scientist, University of Tuebingen
Alexander Wentzel
Senior Researcher, SINTEF Industry
Marc Chevrette
Assistant Professor, University of Florida
Julia Nepper
Postdoctoral Trainee, University of Wisconsin-Madison
Nancy Keller
Professor, University of Wisconsin
Guy Polturak
Postoctoral researcher, John Innes Centre
Norberto Lopes
Full Professor in Organic Chemistry, University of São Paulo
William Fenical
Distinguished Professor, Scripps Institution of Oceangraphy
Simon Moore
Lecturer in Synthetic Biology, University of Kent
Yousong Ding
Associate Professor, University of Florida
Avena Ross
Associate Professor, Queen's University
Alessandra Eustaquio
Assistant Professor, University of Illinois at Chicago
Programme
MONDAY 16TH MAY 2022 |
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14:00 - 15:00 |
Student Networking Reception |
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14:30 - 15:30 |
Registration & Welcome Reception |
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Session I (Meta)Genomics-Enabled Natural Product Discovery |
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15:30 - 15:40 |
Opening Comments |
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15:40 - 16:15 |
Nancy Keller |
ECOLOGICALLY RELEVANT SECONDARY METABOLITES IN FUNGAL-BACTERIAL COMMUNICATION |
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16:15 - 16:40 |
Cuauhtemoc Licona Cassani |
BIODIVERSITY AND SPECIALIZED METABOLISM: TALES OF NATURAL PRODUCTS FROM MEXICAN ECOLOGICAL NICHES |
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16:40 - 16:55 |
Scarlet Ferrinho |
MINED THE GAP: RECONCILING GENOMIC AND METABOLOMIC DATA OF CYANOBACTERIA |
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16:55 - 17:20 |
Norberto P. Lopes |
THE RATIONAL SEARCH FOR BIOLOGICALLY ACTIVE SUBSTANCES THROUGH MASS SPECTROMETRY |
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17:20 - 17:45 |
Mark Liles |
SOIL MICROORGANISMS AND METAGENOMES AS SOURCES OF ANTI-INFECTIVE METABOLITES |
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17:45 - 18:30 |
Refreshments |
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18:30 - 18:55 |
Meet the Poster Presenters I |
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18:55 - 19:10 |
Benjamin Lichman |
OMICS APPROACHES TO HARNESS DAPHNIPHYLLUM ALKALOID DIVERSITY |
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19:10 - 19:35 |
Guy Polturak |
GENOMICS-DRIVEN DISCOVERY OF CLUSTERED BIOSYNTHETIC PATHWAYS FOR DEFENSE-RELATED MOLECULES IN BREAD WHEAT |
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19:35 - 19:50 |
Meet the Poster Presenters II |
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19:50 |
Dinner at Leisure |
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TUESDAY 17TH MAY 2022 |
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07:00 - 09:00 |
Buffet Breakfast |
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Session II Synthetic Biology to Access and Optimize Natural Products |
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09:00 - 09:35 |
Rolf Müller |
PRECLINICAL OPTIMIZATION OF NATURAL PRODUCTS USING SYNTHETIC BIOLOGY APPROACHES |
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09:35 - 10:00 |
Adrian Keatinge-Clay |
ENGINEERING POLYKETIDE SYNTHASES USING THE CORRECT MODULE BOUNDARY |
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10:00 - 10:25 |
Alessandra Eustaquio |
DEVELOPMENT OF A BURKHOLDERIA BACTERIAL HOST FOR NATURAL PRODUCT DISCOVERY |
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10:25 - 11:10 |
Group Photo, Refreshments & Poster Viewing |
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11:10 - 11:25 |
Kameshwari Chengan |
A RAPID SYNTHETIC BIOLOGY PLATFORM FOR ANTIBIOTIC DISCOVERY IN GRAM-NEGATIVE BACTERIAL PATHOGENS |
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11:25 - 11:50 |
Constance Bailey |
THE INVESTIGATING EFFECTS OF THE FUNCTIONAL CONSEQUENCES OF HETEROLGOUS EXPRESSION ON MEGASYNTHASES FROM ACTINOMYCETES |
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11:50 - 12:15 |
Simon Moore |
A STREPTOMYCES TRANSCRIPTION-TRANSLATION TOOLKIT FOR SYNTHETIC BIOLOGY AND NATURAL PRODUCT APPLICATIONS |
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12:15 - 17:00 |
Lunch at Leisure & Free Time |
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17:00 - 17:25 |
Nigel Mouncey |
NEW KEYS TO UNLOCK THE TREASURE TROVE OF MICROBIAL NATURAL PRODUCTS |
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17:25 - 17:50 |
Evi Stegmann |
GLYCOPEPTIDE BIOSYNTHESES: LEARNING FROM NATURE´S PARADIGMS FOR SYNTHETIC BIOLOGY |
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17:50 - 18:05 |
Álvaro Pérez Valero |
DE NOVO BIOSYNTHESIS OF O-METHYLATED FLAVONOIDS IN THE MICROBIAL FACTORY STREPTOMYCES ALBUS |
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18:05 - 20:05 |
Poster Session & Refreshments |
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20:05 |
Group Dinner |
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WEDNESDAY 18TH MAY 2022 |
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07:00 - 09:00 |
Buffet Breakfast |
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Session III Novel Chemistry and Enzymology of Natural Products and their Analogues |
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09:00 - 09:15 |
Wolfgang Wohlleben |
ENGINEERING THE BIOSYNTHESIS OF IMMUNOSUPPRESSANTS |
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09:15 - 09:30 |
Wei Li Thong |
A CRISPR-CAS9 GENE EDITING APPROACH FOR REPROGRAMMING COMPLEX ANTIBIOTIC ASSEMBLY LINES |
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09:30 - 09:45 |
Jan Claesen |
MINING NATURAL PRODUCTS FROM THE HUMAN SKIN MICROBIOME |
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09:45 - 10:00 |
Dominic Campopiano |
DISCOVERY OF CRYPTIC BACTERIAL SPHINGOLIPID BIOSYNTHESIS REVEALS A CONVERGENT EVOLUTIONARY PATHWAY |
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10:00 - 10:45 |
Refreshments & Poster Viewing |
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10:45 - 11:10 |
Jackie Winter |
UNLOCKING THE CHEMICAL POTENTIAL OF THE FUNGAL TERPENOME |
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11:10 - 11:25 |
Lena Barra |
NAD ACTING AS A BUILDING BLOCK IN NATURAL PRODUCT BIOSYNTHESIS |
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11:25 - 11:40 |
Jan Johannes Crames |
BIOSYNTHESES OF UNUSUAL NON-RIBOSOMAL PEPTIDES |
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11:40 - 11:55 |
Cesar Aguilar |
FLUORINASE BACTERIAL ENZYME AS A BEACON IN THE PURSUIT OF NOVEL NATURAL PRODUCTS |
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11:55 - 17:30 |
Lunch at Leisure & Free Time |
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17:30 - 17:55 |
Marc Chevrette |
DYNAMIC SECONDARY METABOLISM IN A MODEL RHIZOSPHERE COMMUNITY |
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17:55 - 18:10 |
Geng-Min Lin |
ACCESSING THE UNEXPLORED CHEMICAL SPACE OF LABDANE-RELATED DITERPENES VIA METABOLIC ENGINEERING |
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18:10 - 18:35 |
Alexander Wentzel |
NEW NATURAL PRODUCTS FROM MARINE ACTINOBACTERIA AND MICROBIOMES |
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18:35 - 19:20 |
Refreshments & Poster Viewing |
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19:20 - 19:45 |
Avena Ross |
PROBING BIOSYNTHETIC APPROACHES FOR TAMBJAMINE PRODUCTION |
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19:45 - 20:00 |
Florian Hubrich |
RIBOSOMAL LIPOPEPTIDES WITH DISCTINCT FATTY N-ACYL MOIETIES |
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20:00 |
Gala Dinner & Poster Awards |
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THURSDAY 19TH MAY 2022 |
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07:00 - 09:00 |
Buffet Breakfast |
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Session IV Bringing Natural Products to the Market |
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09:00 - 09:35 |
Bill Fenical |
VALIDATING THE STEREOSPECIFICITIES OF TYPE 1 PKS MODULAR ENZYMES IN MACROLIDE BIOSYNTHESIS |
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09:35 - 10:00 |
Tom Ramseier |
MINING THE PAN-FUNGAL KINGDOM FOR GENETICALLY ENCODED SMALL MOLECULES (GEMs) |
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10:00 - 10:25 |
Yousong Ding |
AN INTEGRATED PIPELINE FOR DISCOVERY AND PRODUCTION OF BIOACTIVE MARINE NATURAL PRODUCTS |
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10:25 - 10:40 |
Devin Scannell |
TARGETED DISCOVERY OF NATURAL PRODUCTS OF INTEREST FROM MASSIVE METAGENOMIC DIVERSITY |
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10:40 - 11:10 |
Refreshments |
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11:10 - 11:25 |
Robert Stankey |
NEW TOOLS FOR TARGETED CLONING AND OVER EXPRESSION OF BIOSYNTHETIC GENE CLUSTERS |
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11:25 - 11:50 |
Bill Kinney |
SYNTHETIC AND BIOSYNTHETIC APPROACHES TO A NEW MAMMALIAN AMINOSTEROL (ENT-03) WITH PROFOUND METABOLIC ACTIVITY |
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11:50 - 12:15 |
Julia Nepper |
A BACILLUS CEREUS ANTIBIOTIC AFFECTS PHYSIOLOGY OF AN ECOLOGICAL NEIGHBOR |
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12:15 - 12:30 |
Chengcang Charles Wu |
OPEN NEW DOORS TO EFFICIENTLY DISCOVER AGRICULTURAL CHEMICALS AND DRUGS AS FUNGAL NATURAL PRODUCTS BY FUNGAL ARTIFICIAL CHROMOSOME (FAC) TECHNOLOGY |
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12:30 - 12:40 |
Closing Comments |
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Supported by
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Contact usVenue & Location
Fiesta Americana Condesa Cancun All Inclusive
This stylish hotel features contemporary Mexican architecture, including one of the largest and most impressive thatched-roof "palapas" in the entire country. There are cultural activities, arts and crafts and sports programs to keep you constantly entertained, plus time to relax and enjoy the Mayan culture, soak up the Caribbean sunshine and revel in the international ambiance that settles in after the sun goes down.
Throughout your stay delegates will enjoy a full meal plan, inclusive of beverages. Take your pick from the aromatic Asian delights at Kaumbu, traditional fare at El Mexicano, delicious international cuisine at Kalmia Buffet or perhaps sample the sumptuous Italian dishes at Rosato. There are also several other dining opportunities such as the Cevichería, Pizzeria, Sushi Corner, pool and lounge bar areas. The Gala Night with either a Mayan or Caribbean theme takes place on the third evening of the conference with a mouth-watering feast of local cuisine, an open bar and amazing local entertainment. We welcome all delegates and their accompanying persons to the Gala Night – a truly fun filled night not to be missed!
Hotel Facilities
- Lagoon Pool
- Extensive Health Club and Spa
- Complimentary Wi-Fi in guest rooms and throughout hotel and conference areas
General Information
Venue Rating
★ ★ ★ ★ ★
Currency
US Dollar (USD)
Address
Fiesta Americana Condesa Cancún All Inclusive Blvd. Kukulcan km 16.5 Zona Hotelera 77500 Cancun Q.R. Mexico
Nearest Airport
Cancun International Airport
Location
Cancun is a delightful combination of natural beauty, islands, ecological reserves and white sandy beaches. However, besides sun, sand and sea, this destination also offers an infinite variety of underwater activities to choose from: the diving, snorkelling and fishing here are outstanding and you will find an undersea world packed with tropical fish that live on the second largest barrier reef in the world. Sports enthusiasts might choose one of the many eco-tourism activities, such as cycling or hiking through the tropical forest or kayaking through mangroves, or something a little more adventuresome, like zip lining through the treetops.
Apart from the more well-known ancient Mayan archealogical sites such as Tulum, Cobá and Chichén Itzá you may like to visit the Aktun Chen caverns, voted one of the Top 10 underwater walks by National Geographic described as a truly magical experience.
Conference History
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Media Partners
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Conference Manager
Chloe Trundle
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