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2nd Synthetic Biology for Natural Products Conference
The Interface of (Meta)Genomics, Synthetic Biology and Natural Product Discovery
02 Jun - 05 Jun 2019
Puerto Vallarta, Mexico
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David Mead
Terra Bioworks
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Nigel Mouncey
DOE Joint Genome Institute
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Charles Moore
Novartis Pharma AG
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Michael Burkart
University of California, San Diego
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Michael Thomas
University of Wisconsin-Madison
Early Bird - Expired • Talk Submission - Expired • Poster Submission - Expired • Registration & Payment Deadline - Expired
Synopsis
Genome sequencing has revealed an enormous untapped biosynthetic capacity for microbial natural products, only a small fraction of which are represented in fermentation-based screens. Synthetic biology tools are being developed to translate the encoded diversity of microbial biosynthetic pathways into novel compounds and natural products. The Synthetic Biology of Natural Products conference will blend these disciplines with the goal of generating new platforms, tools and technologies to capture, manipulate and engineer natural product genes and pathways. Converting this vast untapped (meta)genomic diversity into novel chemical leads for biomedical and agricultural applications will require breakthroughs in design, scale and biologics that currently limit the field.
Key Sessions
- (Meta)Genomics-Enabled Natural Product Discovery
- New Tools for Capturing, Manipulating and Activating Biosynthesis Pathways
- Heterologous Expression and Synthetic Biology Technologies
- Trends in the Commercialization of Natural Products
Student Offer
Take advantage of this fantastic opportunity for students! Register an academic at the rate of $1,755 and bring a student for only $700. Unfortunately, Postdocs are not eligible for this offer. Both registration packages include; accommodation for the 02, 03, 04 June 2019 (on a shared basis for students) and a 24hour all-inclusive food and beverage package for the conference period. Once registered, please contact Jack Peters to obtain a special registration link for your student.
Confirmed Invited Speakers
Ikuro Abe (The University of Tokyo)
Tyler Backman (LBNL)
Francisco Barona-Gómez (Cinvestav-IPN)
Richard Baltz (CognoGen Biotechnology Consulting)
Dominic J. Campopiano (University of Edinburgh)
Guy Carter (Biosortia Pharmaceuticals)
Marc Chevrette (University of Wisconsin)
Yousong Ding (University of Florida)
Alessandra Eustaquio (University of Illinois at Chicago)
Sylvie Garneau-Tsodikova (Univeristy of Kentucky)
Rebecca Goss (University of St. Andrews)
Daniel Gray (WarpDrive Bio)
Martin Grininger (University Frankfurt)
Jo Handelsman (University of Wisconsin)
Nancy Keller (University of Wisconsin)
Amy Lane (University of North Florida)
Anita Loeschcke (Heinrich Heine University Düsseldorf)
Nathan Magarvey (McMaster University)
Marnix Medema (Wageningen University and Research)
Elliot Miller (Corteva AgriScience)
Doug Mitchell (University of Illinois at Urbana-Champaign)
Alison Narayan (University of Michigan)
Markus Nett (TU Dortmund)
Anne Osbourn (John Innes Centre)
Philippe Prochasson (LifeMine Therapeutics)
Martin Schmeing (McGill University)
Michael Smanski (University of Minnesota)
Robb Stankey (Varigen)
Yi Tang (UCLA)
Oleg Tsodikov (University of Kentucky)
Tilmann Weber (Technical Univ. Denmark)
Alexander Wentzel (SINTEF)
Gavin Williams (North Carolina State University)
Jaclyn Winter (University of Utah)
Alexandre Zanghelini (Arzeda)
Wenjun Zhang (UC Berkeley)
Nadine Ziemert (University of Tubingen)
Target Audience
Synthetic biology scientists and companies looking to learn the latest engineering and synthetic biology technologies for converting small molecule, natural product pathways into novel compounds. Topics discussed during the conference will span the experimental spectrum from molecular biology, microbiology, drug discovery, chemistry and pharmacology, to antibiosis activities against cancer, viral and microbial pathogens, as well as biocontrol and biostimulants.
Educational Need
A new generation of tools and technologies is needed to convert the vast biodiversity found in natural product pathways into bioactive compounds and treatments. The Synthetic Biology of Natural Products conference will bring together a broad spectrum of research scientists and corporate managers interested in learning about the latest developments in this new field.
Confirmed Speakers
Chairs
David Mead
CEO & Co-founder, Terra Bioworks
Nigel Mouncey
Director, DOE Joint Genome Institute
Charles Moore
Research Investigator, Novartis Pharma AG
Michael Burkart
Professor, University of California, San Diego
Michael Thomas
Professor, University of Wisconsin-Madison
Invited Speakers
Douglas Mitchell
Alumni Research Scholar Professor, University of Illinois at Urbana-Champaign
Nadine Ziemert
Professor, University Tuebingen
Guy Carter
Chief Scientific Officer, Biosortia Pharmaceuticals
Robert Stankey
Principal Scientist, Terra Bioforge
Markus Nett
Professor, TU Dortmund University
Gavin Williams
Associate Professor, NC State University
Marnix Medema
Assistant Professor, Wageningen University
Tyler Backman
Postdoctoral Fellow, Lawrence Berkeley National Laboratory
Alessandra Eustaquio
Assistant Professor, University of Illinois at Chicago
Tilmann Weber
Professor / Co-Principal Investigator, Technical University of Denmark
Wenjun Zhang
Associate Professor, UC Berkeley
Ikuro Abe
Professor, The University of Tokyo
Jaclyn Winter
Assistant Professor, University of Utah
Alexander Wentzel
Senior Researcher, SINTEF Industry
Anita Loeschcke
Junior Group Leader, Heinrich Heine University Düsseldorf
Martin Grininger
Professor of Biomolecular Chemistry, University Frankfurt
Yousong Ding
Associate Professor, University of Florida
Martin Schmeing
Ass Prof, McGill University
Philippe Prochasson
Director, LifeMine Therapeutics
Francisco Barona-Gomez
Professor, Langebio - Cinvestav
Mike Smanski
Assistant Professor, University of Minnesota
Marc Chevrette
Assistant Professor, University of Florida
Richard Baltz
Chief Scientific Officer, CognoGen Biotechnology Consulting
Elliot Miller
Lead Molecular Microbiologist, Corteva Agriscience
Daniel Gray
Senior Program Director, Ginkgo Bioworks
Amy Lane
Associate Professor, University of North Florida
Alexandre Zanghellini
Co-Founder and CEO, VP Research, Arzeda Corp
Yi Tang
Professor, University of California Los Angeles
Jo Handelsman
Director, Wisconsin Institute for Discovery
Alison Narayan
Assistant Professor, University of Michigan
Rebecca Goss
Professor, University of St Andrews
Sylvie Garneau-Tsodikova
Professor, University of Kentucky
Oleg Tsodikov
Associate Professor, University of Kentucky
Dominic Campopiano
Professor, University of Edinburgh
Nathan Magarvey
Professor, McMaster University
Programme
SUNDAY 2ND JUNE 2019 |
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13:30 – 14:30 |
Student Networking Lunch |
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14:00 – 15:00 |
Registration & Welcome Reception |
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(Meta) Genomics-Enabled Natural Product Discovery |
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15:00 – 15:10 |
Opening Comments |
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15:10 – 15:45 |
Jo Handelsman |
CHEMICAL DIVERSITY FROM THE SOIL MICROBIOME |
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15:45 – 16:10 |
Nathan Magarvey |
FUNCTIONS AND DISCOVERY OF PEPTIDE ANTIBIOTICS VIA ARTIFICIAL INTELLIGENCE |
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16:10 – 16:35 |
Nadine Ziemert |
COMPUTATIONAL GENOME MINING TOOLS FOR THE DISCOVERY OF BACTERIAL NATURAL PRODUCTS |
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16:35 – 17:00 |
Doug Mitchell |
HIGH-THROUGHPUT RiPP DISCOVERY |
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17:00 – 17:15 |
Nigel Mouncey |
EXPANDING THE NATURAL PRODUCTS GALAXY THROUGH METAGENOMICS |
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17:15 – 18:00 |
Refreshments |
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18:00 – 18:25 |
Wenjun Zhang |
GENOMICS-ENABLED NATURAL PRODUCT DISCOVERY |
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18:25 – 18:50 |
Marc Chevrette |
MINING MICROBIOMES FOR ANTIMICROBIALS |
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18:50 – 19:05 |
Alison Murray |
MICROBIOME EXPLORATIONS OF A UNIQUE MACROLIDE-PRODUCING ANTARCTIC ASCIDIAN |
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19:05 – 19:30 |
Alexander Wentzel |
EXPANDING THE (META)GENOMICS TOOLBOX FOR THE DISCOVERY AND PRODUCTION OF NOVEL NATURAL PRODUCTS FROM MICROBIAL RESOURCES |
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19:30 – 19:55 |
Marnix Medema |
COMPUTATIONAL OMICS APPROACHES TO NATURAL PRODUCT DISCOVERY |
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19:55 |
Group Dinner |
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MONDAY 3RD JUNE 2019 |
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07:00 – 08:30 |
Buffet Breakfast at Chulavista |
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Advances in Natural Product Engineering I |
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08:30 – 08:55 |
Dominic J. Campopiano |
OVERCOMING EVOLUTION TO ENGINEER DESIGNER BIOCATALYSTS |
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08:55 – 09:20 |
Martin Grininger |
ENGINEERING FATTY ACID SYNTHASES (FASs) FOR CUSTOM COMPOUND SYNTHESIS |
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09:20 – 09:35 |
Stephan Thies |
RECOMBINANT BACTERIAL CELL FACTORIES FOR DISCOVERY, TAILORING, AND PRODUCTION OF BIOSURFACTANTS |
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09:35 – 10:00 |
Alison Narayan |
BIOCATALYSIS AND COMPLEX MOLECULE SYNTHESIS |
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10:00 – 10:45 |
Group Photo, Refreshments & Poster Viewing |
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10:45 – 11:10 |
Ikuro Abe |
UNUSUAL ENZYME REACTIONS IN NATURAL PRODUCT BIOSYNTHESIS |
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11:10 – 11:25 |
Anna Lisa Camus |
ACCESSING BACKBONE-MODIFIED NONRIBOSOMAL PEPTIDES THROUGH ENZYME ENGINEERING |
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11:25 – 11:50 |
Alessandra EustaquioUniversity of Illinois at Chicago |
HARNESSING BACTERIAL GENOMES AND SYNTHETIC BIOLOGY FOR DRUG DISCOVERY |
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11:50 – 12:25 |
Meet the Poster Presenters |
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12:25 – 17:00 |
Lunch at Leisure |
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Advances in Natural Product Engineering II |
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17:00 – 17:25 |
Yi Tang |
NATURAL PRODUCT GENOME MINING IN FUNGI |
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17:25 – 17:50 |
Nancy Keller |
SECRETS TO UNLOCKING THE FUNGAL METABOLOME |
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17:50 – 18:15 |
Gavin Williams |
NEW-TO-NATURE ISOPRENOIDS AND POLYKETIDES VIA PRECURSOR-DIRECTED BIOSYNTHESIS |
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18:15 – 18:30 |
Hajo Kries |
BIOSYNTHETIC DESIGN OF NONRIBOSOMAL PEPTIDE BIOSYNTHESIS |
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18:30 – 20:15 |
Poster Session & Refreshments |
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20:15 |
Dinner at Leisure |
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TUESDAY 4TH JUNE 2019 |
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07:00 – 08:30 |
Buffet Breakfast at Chulavista |
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IV Trends in the Commercialization of Natural Products |
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08:30 – 09:05 |
Richard Baltz |
SYNTHETIC BIOLOGY AND NATURAL PRODUCT DRUG DISCOVERY |
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09:05 – 09:30 |
Elliot Miller |
OVERCOMING STRAIN ENGINEERING CHALLENGES TO INCREASE PRODUCTION OF UK-2A, THE PRECURSOR OF THE FUNGICIDE INATREQ™ ACTIVE |
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09:30 – 09:55 |
Daniel Gray |
HARNESSING GENOMIC INFORMATION AND SYNTHETIC BIOLOGY TO ENGINEER THE BIOSYNTHESIS OF NOVEL NATURAL PRODUCTS |
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09:55 – 10:20 |
Tyler Backman |
COMPUTER AIDED POLYKETIDE SYNTHASE (PKS) DESIGN |
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10:20 – 11:05 |
Refreshments & Poster Viewing |
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11:05 – 11:30 |
Philippe Prochasson |
FROM COMPOST TO CAPSULES: MINING FUNGAL GENOMES FOR TRANSFORMATIVE HUMAN THERAPEUTIC |
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11:30 – 11:55 |
Alexandre Zanghelini |
NATURAL PRODUCT DISCOVERY OR COMPUTATIONAL DESIGN? IN-VITRO SAMPLING OF NEW MOLECULAR SCAFFOLDS WITH COMPUTATIONAL ENZYME AND PATHWAY DESIGN |
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11:55 – 12:20 |
Guy Carter |
CYANOBUFALINS: NOVEL CARDIOACTIVE TOXINS FROM CYANOBACTERIAL BLOOMS |
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12:20 – 12:35 |
Patrick Gerlinger |
IDENTIFYING BOTTLENECKS IN AN ENGINEERED POLYKETIDE SYNTHASE |
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12:35 – 16:30 |
Lunch at Leisure |
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New Tools for Capturing, Manipulating and Activating Biosynthesis Pathways |
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16:30 – 16:55 |
Markus Nett |
GENETIC TOOLS FOR DIRECTING NATURAL PRODUCT BIOSYNTHESIS IN MYXOBACTERIA |
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16:55 – 17:20 |
Yousong Ding |
IN VIVO AND IN VITRO SYNTHETIC BIOLOGY APPROACHES TO THE PRODUCTION OF HERBICIDAL CYCLIC DIPEPTIDES |
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17:20 – 17:45 |
Anita Loeschcke |
THE P. PUTIDA rRNA OPERONS: EXCEPTIONALLY SUITED CHROMOSOMAL SITES FOR NATURAL PRODUCT GENE CLUSTER EXPRESSION |
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17:45 – 18:00 |
Robert Stankey |
NEW TOOLS FOR TARGETED CLONING AND OVER EXPRESSION OF BIOSYNTHETIC GENE CLUSTERS |
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18:00 – 18:45 |
Refreshments & Poster Viewing |
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18:45 – 19:10 |
Michael Smanski |
DESIGNED BIOSYNTHESIS OF A NATURAL PRODUCT OF UNKNOWN ORIGIN |
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19:10 – 19:35 |
Tilmann Weber |
INTEGRATION OF INFORMATICS, METABOLIC ENGINEERING AND SYNTHETIC BIOLOGY FOR THE DISCOVERY AND ANALYSIS OF NATURAL PRODUCTS |
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19:35 – 20:00 |
Francisco Barona-Gómez |
EVOLUTIONARY AND ECOLOGICAL (META) GENOME-MINING OF NATURAL PRODUCTS |
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20:00 |
Gala Dinner & Poster Awards |
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WEDNESDAY 5TH JUNE 2019 |
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07:00 – 09:00 |
Buffet Breakfast at Chulavista |
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Natural Biosynthetic Enzyme Structure and Activity |
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09:00 – 09:25 |
Martin Schmeing |
STRUCTURES AND FUNCTIONS OF NONRIBOSOMAL PEPTIDE SYNTHETASES |
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09:25 – 09:50 |
Rebecca Goss |
GENOCHEMETIC TOOLS FOR BLENDING SYNTHETIC CHEMISTRY WITH THE SYNTHETIC BIOLOGY OF NATURAL PRODUCTS |
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09:50 – 10:15 |
Amy Lane |
ASSEMBLY AND MANIPULATION OF BIOSYNTHETIC PUZZLE PIECES YIELDING DIKETOPIPERAZINE NATURAL PRODUCTS |
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10:15 – 10:45 |
Refreshments |
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10:45 – 11:10 |
Sylvie Garneau-Tsodikova |
ENGINEERING MULTIFUNCTIONAL ENZYMES FOR NONRIBOSOMAL PEPTIDE SYNTHESIS |
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11:10 – 11:35 |
Jaclyn Winter |
DEVELOPING HETEROLOGOUS EXPRESSION PLATFORMS FOR ELUCIDATING FUNGAL TERPENE BIOSYNTHESIS |
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11:35 – 12:00 |
Oleg Tsodikov |
VERSATILITY OF ENZYMATIC HALOGENATION |
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12:00 – 12:10 |
Closing Comments |
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Supported by
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Contact usVenue & Location
Fiesta Americana Puerto Vallarta All Inclusive
The Fiesta Americana Puerto Vallarta All Inclusive is in the beautiful Bahía de Banderas on the Pacific Coast of Mexico. With a mix of contemporary Mexican architecture and the more traditional Mexican styles of Jalisco, the buildings blend perfectly with the surrounding landscape of the Western Sierra Madre Mountains.
Located just 13km from Licenciado Gustavo Díaz Ordaz International Airport and within easy reach of the town of Puerto Vallarta with its array of boutique shops and set alongside one of the most beautiful beaches in the area, this provides the perfect setting for a conference.
Throughout your stay delegates will enjoy a full meal plan, inclusive of beverages. Take your pick from the wonderful selection of restaurants such as Chulavista, a contemporary buffet restaurant overlooking the beach offering Mexican and International cuisine, Rosato, offering mediterranean cuisine with an Italian twist, El Mexicano, serving traditional Mexican fare, Tiatang, adults-only restaurant serving Asian cuisine nightly for dinner and L'Isola, a sophisticated restaurant serving lobster and fine meat cuts in a poolside setting - there is a surchage for dining at this venue. There are also several other dining opportunities such as the Cevichería, Fajita House and Grill as well as the Terrace and Pool Bars. The Café / Deli Express is also open daily for coffee, teas, cakes and pastries.
The themed Gala Night takes place on the third evening of the conference with a mouth-watering feast of local cuisine, an open bar and amazing local entertainment. We welcome all delegates and their accompanying persons to the Gala Night – a truly fun filled night not to be missed!
Hotel facilities include;
- Complimentary Wi-Fi in guest rooms and throughout hotel and conference areas
- Lagoon Pool
- Spa
- Fitness Center
- 8 Restaurants
- Kids Club
- Private Beach
General Information
Venue Rating
★ ★ ★ ★
Currency
US Dollar (USD)
Address
Blvd Francisco Medina Ascencio Km 2.5, Puerto Vallarta 48300, Mexico
Nearest Airport
Licenciado Gustavo Diaz Ordaz International Airport (PVR)
Location
Originally a bustling mining town known as the ‘Las Peñas’ in the 19th century, Puerto Vallarta is framed by the stunning mountains of the Sierra Madre Occidental of Jalisco and the immense Mexican Pacific. This fascinating destination with red roofs, golden sunsets, cobbled streets and beautiful beaches possesses everything that makes for an incredible place to visit.
Puerto Vallarta’s art offering is amazing, from crafts found in the flea market to the fleeting creations made by artists with the sand on the beach. Its art galleries, boardwalk, calm Banderas Bay waters - loved by scuba diving enthusiasts and bustling nightlife bare some of the contrasts that Vallarta holds.
There are many activities you can enjoy during your fee time such as visiting the El Salado estuary, going on horseback up the Quimixto waterfall or taking a tour of Banderas Bay. You may also like to explore the Jardín Botánico de Vallarta where you will find orchids, bromeliads, agaves, wild palms and fern grottos along the paths of this gorgeous nature park.
Conference History
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Media Partners
If you're interested in sponsoring this conference please contact us.
Conference Manager
Jack Peters
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