Registration deadlines
Early Bird - Expired
Talk Submission - Expired
Poster Submission - Expired
Registration Deadline - Expired
10 Oct 2024 - 13 Oct 2024
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St. Julians, Malta
Chairs
The 4th Epigenetics conference was held at the Hilton Malta, St. Julians, Malta, from 10 - 13 October 2024. There were 56 registrations and, concerning the geographical breakdown of participants, 48% came from European countries, 32% from the US, 20% from countries from the rest of the world. Concerning the career status of the participants, 24% are students, 69% are academics, and 7% have positions in industry.
The 4th meeting on “Epigenetics, From Mechanisms to Disease” gathered an outstanding mix of young scientists, junior and established principal investigators with interdisciplinary expertise in many fields related to epigenetics. The 37 talks were of outstanding quality and presented a broad spectrum of topics united by the general aim of understanding life in healthy conditions, upon aging and during onset and progression of diseases such as neurodegenerative diseases but also neurodevelopmental syndromes as well as pediatric and adult cancers. Very lively poster sessions were attended by all participants, including junior and senior PIs, and three poster prizes were awarded, including one awarded from the ‘EMBO Molecular Medicine’ journal.
As an outcome, we learnt a great deal about transcription regulation, the role of chromatin components such as chromatin remodelers, histone modifiers, readers, Polycomb and heterochromatin, as well as the role of noncoding RNAs. The approaches ranged from in vitro systems and biochemistry, to molecular, cell and developmental biology of model and non-model organisms, including sophisticated in vitro cell differentiation approaches and organoid culture models and reaching all the way to patient samples. The discussion sessions were extremely lively, so much so that session chairs had frequently to stop people asking for the sake of time. They frequently challenged the dogmas in a constructive and creative way, particularly concerning the role of Polycomb proteins in gene regulation and in cancer and the role of epigenetic modifications versus mutations in the process of tumorigenesis. Very promising avenues for a next generation of molecules, including protein degrader molecules that are stirring a huge interest in the pharma industry, were also presented and discussed. It is important to note that very often questions were made from young scientists, which indicate that we succeeded in generating an informal and friendly atmosphere throughout the meeting. Finally, short talks selected from abstracts were considered by many participants to be of an excellent level, not only for the quality and novelty of data discussed but also for the overall presentation.
The meeting also included a brainstorming session, where many participants at all levels of age and responsibility proposed topics that might be included in future meetings and suggested ways to boost participant’s interactions and collaborations even more. Many of the participants expressed their excitement and gratitude for the quality of the meeting and its unique atmosphere blending excellence to good spirit! They clearly gave us the feeling that they had been in for a treat!
The workshop format with a limited number of participants, a dense program with a good amount of time left to informal interactions is perfect and unique. Only some other workshops match this, while all other conferences are less exciting due to either the fact that they are too large, making participant interactions very difficult, particularly between young and more established scientists (both categories of attendants tend to stay with their peers rather than reaching out to the other one), or to the fact that only few of the famous established scientists attend small workshops, they tend to attend big conferences instead. Fortunately, this was not at all the case at our meeting, which had spectacularly invited speakers intermingling with young, motivated scientists with many fresh and forward-looking ideas. This format also allows us to share many unpublished data, which is rarely seen in other larger meetings.
The location and venue were very pleasant and contributed to the success of the meeting. The sea is stunning and the style of the venue casual but very comfortable. Food was also generally good, although it could be improved if discussed with the Hotel manager.
As a final note, this success is not only that of the participants’ engagement, but equally that of the great Fusion crew and of the excellent venue they have picked. Congratulations Fusion, the epigenetic community is already looking forward to the next chance!
Conference Chairs, Giacomo CAVALLI (Institute of Human Genetics) and Luciano DI CROCE (Centre for Genomic Regulation)
10 Oct 2024 - 13 Oct 2024
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St. Julians, Malta
Chairs
Chromatin is the template of life, the carrier of genetic information and the core regulator of fundamental processes such as gene expression and stem cell fate determination. Chromatin dysfunction on the other hand can trigger various diseases, including cancer. Although chromatin structure and function and the mechanisms of disease and their diagnostic and therapeutic approaches are the subject of many meetings, conferences bringing them together are less frequent. The boundaries among these various disciplines are disappearing and meeting on "Epigenetics: from mechanisms to disease" will focus on the discussion of the role of chromatin architecture, epigenetics, stem and single cell biology in cancer and other diseases. The talks will cover a broad range of topics, including chromosome organisation, long-range interactions, chromatin assembly, stem cell regulation/differentiation, RNA-based mechanisms, transcription regulation, DNA methylation and hydroxymethylation, exploiting the power of genome engineering technologies, single-cell approaches, cutting edge epigenomics and imaging approaches and novel cell systems such as organoids.
Speakers have been selected to broadly reflect lessons learned from a variety of model organisms and experimental approaches. Young scientists will take center stage, presenting their work through a large number of talks selected from submitted abstracts as well as through poster presentation. The program has also allocated ample time for exchanging ideas and discussing novel hypotheses at the end of each session, as well as time for informal interactions and networking.
Genevieve Almouzni (Institut Curie)
HISTONE VARIANTS AND THEIR PARTNERS SHAPING CHROMATIN AND CELL FATE
Salvador Aznar-Benitah (IRB Barcelona)
INTRAGENERATIONAL EPIGENETIC INFLUENCE OF FATTY ACIDS ON LIVER DISEASE AND CANCER
Adrian Bracken (Trinity College Dublin)
POLYCOMB REPRESSIVE COMPLEXES IN DEVELOPMENT AND CANCER
Anne Brunet (Stanford University)
SPATIOTEMPORAL TRANSCRIPTOMIC PROFILING AT SINGLE-CELL RESOLUTION IDENTIFIES CELL PROXIMITY EFFECTS OF AGING AND REJUVENATION
Ian Chambers (University of Edinburgh)
TRANSCRIPTION FACTOR CONTROL OF IDENTITY IN PLURIPOTENT AND GERMLINE CELLS
Danette Daniels (Foghorn Therapeutics)
TARGETING CHROMATIN REGULATORY PROTEINS AND DISEASE WITH THERAPEUTIC DEGRADERS
Yael David (Sloan Kettering Institute)
THINKING OUTSIDE THE CHROMOSOME: INTERROGATING EPIGENETIC MECHANISMS IN NONCANONICAL CHROMATIN SPECIES
Francois Fuks (Université Libre de Bruxelles)
RNA MODIFICATIONS IN HEALTH AND DISEASE
Meritxell Huch (Max Planck Institute of Molecular Cell Biology and Genetics)
LIVER ORGANOIDS TO STUDY EPIGENETIC MECHANISMS OF REGENERATION AND CANCER
Tony Kouzarides (Gurdon Institute)
RNA MODIFICATIONS PATHWAYS IN CANCER
Rob Martienssen (Cold Spring Harbour Laboratory)
CHROMATIN REMODELING OF HISTONE H3 VARIANTS BY DDM1HELLS UNDERLIES EPIGENETIC INHERITANCE AND CENTROMERE FUNCTION
Lluis Morey (Sylvester Comprehensive Cancer Center)
ROLE OF POLYCOMB PROTEINS IN CANCER AND DEVELOPMENT
Vera Pancaldi (Inserm Cancer Research Center of Toulouse)
STUDYING CHROMATIN ORGANISATION IN DIFFERENTIATION AND CANCER: AN EVOLUTIONARY PERSPECTIVE
Danny Reinberg (University of Miami)
EPIGENETICS AND INHERITANCE
Yang Shi (Ludwig Cancer Research)
CHROMATIN REGULATION AND HUMAN DISEASES
Ramin Shiekhattar (Sylvester Comprehensive Cancer Center)
INTEGRATOR COMPLEX IN HEALTH AND DISEASE
Ali Shilatifard (Northwestern University)
EPIGENETIC REGULATION OF GENE EXPRESSION IN DEVELOPMENT AND DISEASE
Maria-Elena Torres-Padilla (Helmholtz Zentrum München)
EPIGENETIC MECHANISMS OF CELLULAR PLASTICIY AND REPROGRAMMING TO TOTIPOTENCY
Roser Vento-Tormo (Wellcome Sanger Institute)
AN INTEGRATED SINGLE-CELL MULTIOMICS MAP OF HUMAN BONE MARROW ACROSS ITS LIFESPAN
Ashley Webb (Buck Institute)
EPIGENETIC MECHANISMS UNDERLYING SEX DIFFERENCES IN BRAIN AGING
Take advantage of this fantastic opportunity for students! Fully paying ‘single’ or ‘shared’ registrants can bring a student for only €990. Unfortunately, Postdocs are not eligible for this offer. Both registration packages include; accommodation for the 10, 11, 12 October 2024 (on a shared basis for students) and a food and beverage package for the conference period. Once registered, please contact Rosie Johnson to obtain a special registration link for your student.
The strong educational asset of this workshops is to enhance communication between junior and senior investigators. In particular, we are paying a strong attention towards fostering the chance for young scientists to present their work through a large number of short talks selected from submitted abstracts as well as through poster presentation. We allocated ample time for exchanging ideas and discussing novel hypothesis at the end of each session, as well as for informal interactions and networking. A career and Diversity, Equity and Inclusion round table will also be organized during the meeting.
This conference will be an ideal setting for PhD students, post-doc and group leaders working in the field of chromatin architecture, epigenetics, stem cell biology, single-cell biology, organoids and cancer. Scientists active in R&D of small, medium and big pharma or biotech companies will find an exciting new set of inputs and an interactive forum for exchange with academia.
10 Oct 2024 - 13 Oct 2024
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St. Julians, Malta
Chairs
Genevieve Almouzni
Institut Curie
Salvador Aznar-Benitah
IRB Barcelona
Adrian Bracken
Trinity College Dublin
Anne Brunet
Stanford University
Ian Chambers
University of Edinburgh
Danette Daniels
Foghorn Therapeutics
Yael David
Sloan Kettering Institute
Francois Fuks
Université Libre de Bruxelles
Meritxell Huch
Max Planck Institute of Molecular Cell Biology and Genetics
Tony Kouzarides
Gurdon Institute
Rob Matienssen
Cold Spring Harbour Laboratory
Lluis Morey
Sylvester Comprehensive Cancer Center
Vera Pancaldi
Inserm Cancer Research Center of Toulouse
Danny Reinberg
University of Miami
Yang Shi
Ludwig Cancer Research
Ramin Shiekhattar
Sylvester Comprehensive Cancer Center
Ali Shilatifard
Northwestern University
Maria-Elena Torres-Padilla
Helmholtz Zentrum München
Roser Vento-Tormo
Wellcome Sanger Institute
Ashley Webb
Buck Institute
10 Oct 2024 - 13 Oct 2024
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St. Julians, Malta
Chairs
10 Oct 2024 - 13 Oct 2024
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St. Julians, Malta
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10 Oct 2024 - 13 Oct 2024
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St. Julians, Malta
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| Ticket Type | Early Bird | Full Price |
|---|---|---|
|
Single
Choose this option if you will be attending the conference alone, or if you will bring accompanying guests that will not attend the meeting.
|
€2216 | €2312 |
|
Shared
Choose this option if you wish to share with a colleague who is also attending the conference, or if you wish to be paired with another attendee of the same sex.
|
€1943 | €2039 |
|
Student
Choose this option if you are a student. Please note all students will be paired with another attendee of the same sex if a room sharer is not specified. If you wish to have your own room, please register under the Single option.
|
€1847 | €1943 |
Adult
€478
Child
€10
Adult
€244
Child
€0
All registration fees include 3 nights accommodation and meals during the conference period. Exact inclusions are detailed below.
All registration fees include 3 nights accommodation and meals during the conference period. Exact inclusions are detailed below.
Our registration fees are inclusive of the following during the conference period only:
- Conference registration
- 3 nights’ fixed accommodation (10, 11, 12 October 2024) on a single or shared basis.
- Buffet breakfast in Oceana restaurant
- Buffet lunch in the in Oceana restaurant with two soft drinks or juices, coffee/tea and water
- Buffet dinner in the in Oceana restaurant, plus two drinks vouchers (can be exchanged for a glass of house wine, glass of house beer, or soft drink)
- BBQ Gala Dinner with three drink tickets (can be exchanged for a glass of house wine, glass of house beer or soft drink)
- Two drink tickets during the poster session (can be exchanged for a glass of house wine, glass of house beer or soft drink)
- Complimentary WIFI in both conference rooms and guest room
Our accompanying adult fees are inclusive of the following during the conference period only:
- 3 nights’ fixed accommodation (10, 11, 12 October 2024) on a shared basis with a conference participant
- Buffet breakfast in Oceana restaurant
- Buffet lunch in the in Oceana restaurant with two soft drinks or juices, coffee/tea and water
- Buffet dinner in the in Oceana restaurant, plus two drinks vouchers (can be exchanged for a glass of house wine, glass of house beer, or soft drink)
- BBQ Gala Dinner with three drink tickets (can be exchanged for a glass of house wine, glass of house beer or soft drink)
- Complimentary WIFI in guest room
Important Note: Accompanying persons are not permitted access to the conference. Meals are only available during the times listed in the conference programme and accompanying guests must dine with the group.
Our accompanying child fees are inclusive of the following during the conference period only:
- 3 nights’ fixed accommodation (10, 11, 12 October 2024) on a shared basis per adult
- Buffet breakfast in Oceana restaurant
- Buffet lunch in the in Oceana restaurant
- Buffet dinner in the in Oceana restaurant
- BBQ Gala Dinner
- Complimentary WIFI in guest room
Important Note: Meals are only available during the times listed in the conference programme and accompanying children must dine with the group. No beverages are included for children and must be paid on consumption.
Accompanying child fees are applicable for children aged 0-10 years. Children aged 11+ years are classified as an adult.
Please kindly ensure your child / children are supervised at all times during conference and related events. Childcare services are available at the hotel, please contact Rosie for further information.
- 1 night’s accommodation for 1 person
- Buffet breakfast in Oceana restaurant
- Complimentary WIFI in your guest room
Important Note: Extra night child fees are applicable for children aged 0-11 years when accompanied by an adult. Children aged 11+ years are classified as an adult.
10 Oct 2024 - 13 Oct 2024
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St. Julians, Malta
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10 Oct 2024 - 13 Oct 2024
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St. Julians, Malta
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10 Oct 2024 - 13 Oct 2024
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St. Julians, Malta
Chairs
The Epigenetics Research Network is an excellent platform to connect with fellow attendees and likeminded researchers prior to the conference.
The Linkedin Group is designed to bring together the global community of researchers and scientists interested in the role of chromatin architecture, epigenetics, stem and single cell biology in cancer and other diseases.
The group is open to all and is intended as a networking forum for past, present and future participants of Fusion Conferences as well as those interested in the related topics.
10 Oct 2024 - 13 Oct 2024
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St. Julians, Malta
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We are excited to be visiting this beautiful Mediterranean destination in autumn 2024 – the Hilton Malta in St Julian’s, Malta. The oceanfront resort overlooks the stunning Portomaso Marina in St. Julian’s.
This beautiful hotel is located only 15 minutes from the ancient capital city of Valletta, a UNESCO World Heritage Site. Megaliths, medieval dungeons and Calypso’s Cave – The Maltese Islands are positively mythic. As the countryside is dotted with medieval towers, wayside chapels and the oldest known human structures in the world, the Islands have rightly been described as an open-air museum.
This is not an all-inclusive property, but we have arranged a full food and beverage package for delegates during the conference period which is included within the registration fee. Breakfast will be at leisure each morning, but participants will dine together for conference lunches and dinners. For anyone staying any extra nights, the rate will be bed and breakfast only so delegates can choose whether to dine at the hotel or explore and eat elsewhere.
Hotel facilities include;
• Complimentary Wi-Fi in guest rooms and throughout hotel and conference areas
• 4 Seasonal Outdoor Pools
• Spa with Indoor Swimming Pool
• Fitness Center and Tennis Court
• 3 Restaurants
• 2 Bars
Venue Rating
Currency
Euro (EUR)
Address
Vjal Portomaso St Julian's PTM, 01, Malta
Nearest Airport
Malta International Airport
The Hilton Malta overlooks the stunning Portomaso Marina in St. Julian’s. This beautiful hotel is located only 15 minutes from the ancient capital city of Valletta, a UNESCO World Heritage Site.
10 Oct 2024 - 13 Oct 2024
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St. Julians, Malta
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The hotel is approximately 20 minutes from Malta International Airport, the official airport of the Maltese Islands.
Taxis are available outside the airport, however we would strongly recommend you use one of the transport app providers below.
There are 3 options for booking transport with an app- Uber, Bolt and eCabs. They all operate in and around Malta, and the fares are generally cheaper than a taxi. The cost of transfers between Malta International Airport and the city of St Julians generally ranges from €15 to €20.
10 Oct 2024 - 13 Oct 2024
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St. Julians, Malta
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Local activity details will be announced here soon.
10 Oct 2024 - 13 Oct 2024
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St. Julians, Malta
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During afternoon free time on Day 2 (Friday 11th October), you have the opportunity to visit the capital of Malta, Valletta. The guided tour will include Barracca Barrakka Gardens, the fortified Three Cities and breathtaking views of the Grand Harbour.
Price:
The total price of this trip is €53.
Payment will be made online via a portal. We can except VISA, Mastercard, AMEX + ApplePay & GooglePay
Tour Includes
- Round-trip transportation
- Tour of Valletta including Barracca Barrakka Gardens, St John`s Co-Cathedral & the Church Museum.
- Bottle of water
- Guided Tour
To sign up, please email Rosie, if you have any accompanying guests who wish to join as well please note down the names in your email as well.
Please note, sign-ups for both activities are required by Thursday 8th August 2024. Spaces are limited and you will not be able to sign-up after the listed deadline!
Once you have confirmed your participation on the VALLETTA TOUR, you are financially committed. After signing up, should you decide to no longer participate or not show up at the time of the trip, you will still be charged. If you have pre-paid, it will not be refundable.
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Below are the timings that we will share in the final email to those that sign-up and for your reference in case your programmes change etc.
VALLETTA TOUR
12:25pm – 12:55pm Lunch
1:00pm Meet at front of hotel
1:05pm Transport will leave promptly
1:05pm – 1:30pm Transfer
1:30pm – 3:40pm Tour (2.10hrs)
3:50pm – 4:15pm Return transfer *Session starts at 4:45pm
10 Oct 2024 - 13 Oct 2024
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St. Julians, Malta
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10 Oct 2024 - 13 Oct 2024
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St. Julians, Malta
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We have several oral opportunities available at this meeting. To be considered for a talk, please register for the conference and upload your abstract when prompted to do so. You will be able to monitor the status of your abstract through your Fusion account and you will also receive an email if you are successful or unsuccessful.
Please use the abstract template provided (see below) and ensure your abstract is no longer than one page in length.
If you are accepted for a talk, we recommend you check our website regularly as the conference approaches. Regular programme updates will be released under the ‘Programme’ tab on the conference website.
On the day of your presentation please make yourself known to our AV technician who will be present in the conference room. We advise running through your presentation at least 30minutes prior to your session commencing to ensure your slides and any videos or animations appear as expected. We prefer our speakers to run their presentation from the master PC or Mac, however, if you prefer to use your own laptop then please notify us prior to the session. A HDMI or VGA cable is usually available on the podium.
Our AV technician will apply your microphone and provide a combined slide advancer and laser pointer.
We ask all speakers to adhere to their time slots and respect their fellow presenters. A visual traffic light aide will be available to warn presenters as their time decreases.
Please make sure your presentation adheres to the following guidelines.
Aspect Ratio: On Screen Show (16:9)
File Type: Please save your presentation in PPT, PPTS or Keynote format.
10 Oct 2024 - 13 Oct 2024
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St. Julians, Malta
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We have several poster opportunities available at this meeting. To be considered for a poster presentation, please register for the conference and upload your abstract when prompted to do so. You will be able to monitor the status of your abstract through your Fusion account and you will also receive an email if you are successful or unsuccessful.
Please use the abstract template provided (see below) and ensure your abstract is no longer than one page in length.
Our poster boards can accommodate a maximum poster size of A0 (1189H x 841W mm), portrait in orientation. Posters exceeding this size may not fit on the poster boards provided and therefore we may be unable to display your poster, so please kindly keep to these measurements.
Please bring your poster to registration and hand this to a member of the Fusion team. They will advise of your poster number and display your poster for you.
Your poster will remain on display for the duration of the conference, allowing presenters to take advantage of the refreshment breaks and free time for valuable networking opportunities, in addition to the official poster session.
Please check the programme and note the date and time of the poster session(s). Your poster will be judged during the poster session and prizes will be awarded at the Gala Dinner.
Posters will be taken down by the Fusion team and will be ready for collection at the Fusion desk on the final day of the conference.
Download Abstract Template
10 Oct 2024 - 13 Oct 2024
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St. Julians, Malta
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15 Feb 2018, 18 Feb 2018
From Mechanisms to Disease
Fiesta Americana Condesa, Cancun, Mexico
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From Mechanisms to Disease #3EPI22
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The DNA of eukaryotic cells is organized into chromatin. Chromatin is the template of life. It is the vector of genetic information and it is at the core of fundamental processes such as gene regulation, stem cell fate determination and cancer. Th...
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10 Oct 2024, 13 Oct 2024
From Mechanisms to Disease #Epigen24
Hilton Malta, St. Julians, Malta
Chromatin is the template of life, the carrier of genetic information and the core regulator of fundamental processes such as gene expression and stem cell fate determination. Chromatin dysfunction on the other hand can trigger various diseases, i...
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If you are interested in this meeting but not yet ready to register, you can sign up for updates here and our team will keep you updated regarding deadline reminders and grant opportunities relating to this meeting only.
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+44 (0) 1638 555057
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