#NucleicAcids
24 Jul - 27 Jul 2027
Lisbon, Portugal
David Lilley
University of Dundee
Sua Myong
Boston Children's Hospital
Early Bird - 25 Jan 2027 • Talk Submission - 25 Jan 2027 • Poster Submission - 26 Apr 2027 • Registration & Payment Deadline - 26 Apr 2027
DNA and RNA are built from just four nucleotide elements but rich in information content and functional diversity. DNA sequence encodes the cell's genetic blueprint and operating system, and must be copied with unprecedented fidelity once every cell cycle. The integrity of the genetic blueprint is vital to the cell and maintained by various mechanisms to fend off the constant onslaught of DNA damage. In addition to replication, DNA is repeatedly transcribed to RNA for protein synthesis (translation) and cellular regulation (non-coding RNA). Nevertheless, readout of DNA at single-nucleotide level by cellular machineries takes place in the context of the compacted DNA form (chromosomes), within which 2 m of human genomic DNA are compacted and stored in the cell nucleus.
In contrast to the relatively uniform DNA double helix, RNA assumes versatile structure and function. RNA is the worker bee of genetics to the DNA's queen. In addition to its roles as messenger (mRNA), interpreter and amino acid-carrier (tRNA), RNA is also the critical functional part of the ribosome and spliceosome machines and can catalyze peptide bond formation and phosphoryl-transfer reactions (and who knows what more?) as ribozymes. Furthermore, RNA can act as a molecular switch responding to small molecules (riboswitches) to control gene expression or mediating and executing DNA and RNA cleavage as in the CRISPR-Cas defense system. Failure of any of these DNA and RNA transactions can lead to disease. Meanwhile application of antisense oligonucleotide (ASO) and CRISPR-Cas technology have revolutionized gene therapy, and cell and organism manipulation.
Key Sessions
In the 8th Nucleic Acid Conference, the central theme will be to understand processes involving DNA and RNA at the molecular and chemical level, with a marked structural and mechanistic perspective. We plan to have an up-to-date discussion of the following:
• DNA replication in the context of chromatin and telomere
• DNA repair and recombination
• Transcription and splicing
• RNA structure and function
• Translation and post-translation modification
•. Gene editing by ASO and CRISPR-Cas9
• AI-assisted nucleic acid research
David Lilley
University of Dundee
Sua Myong
Boston Children's Hospital
| Ticket Type | Early Bird | Full Price |
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Student Choose this option if you are a student. Please note all students will be paired with another attendee if a room sharer is not specified. Both same-sex and mixed accommodation options available. If you wish to have your own room, please register under the 'Single' ticket option. |
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Shared Choose this option if you wish to share with a colleague who is also attending the conference, or if you wish to be paired with another attendee (same-sex and mixed accommodation options available), or if you have an accompanying adult. |
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Single Choose this option if you will be attending the conference alone and wish to have your own private room. |
| Addition Type | Adult | Child |
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Additional Person This is the cost for an additional adult or child to join you in the same room, for the conference period. Additional guests are not permitted access to the conference. If you wish to extend your stay, please see our 'Extra Night' prices. |
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Extra Night Prices for extra nights apply per person, per night. |
All registration fees include 3 nights accommodation and meals during the conference period. Exact inclusions are detailed below.
Dolce CampoReal Lisboa
The Dolce CampoReal Lisboa is nestled in the scenic region of Torres Vedras, just 30minutes from the city of Lisbon. Set among the rolling hills and vineyards in the countryside, the hotel offers a focused and peaceful environment for conference sessions, whilst still only a short drive away from the hustle and bustle of the city, so attendees can take advantage of all Lisbon has to offer during free time.
The venue has modern, flexible meeting spaces, and due to its smaller size, we are able to offer group dining experiences on each of the conference days, so ideas can continue to be exchanged in a relaxed and informal setting after sessions conclude. For those who need or wish to travel with family, a dedicated kids club and family friendly activities ensure you can balance both work and play.
Outside of sessions, the hotel itself boasts a golf course, tennis courts and wellness facilities for both relaxation and recreation, and the surrounding area is perfect for scenic hikes or nature walks. With the venue nestled in one of Portugal’s renowned wine regions, delegates often enjoy visiting local vineyards for a wine tasting experience during free time.
The blend of both professional and personal experiences make it the perfect setting to reconnect with colleagues, relax with family, and fuel productive conversations to drive research forward.
Conference Currency
Euro (EUR)
Address
R. do Campo (Campo Real) 2565-770 Portugal
Nearest Airport
Lisbon Portela Airport
The Dolce CampoReal Lisboa is nestled between the vineyards and the extraordinary landscape of the Socorro and Archeira Mountains.
Lisbon is only a short 30-minute drive away. The Portuguese capital is constantly recognised as one of the greatest cities in the world, a claim confirmed by the “Lonely Planet Guides", who named Lisbon one of the world’s top 10 cities. Lisbon in one of the world’s oldest cities, predating the likes of London, Rome and Paris by hundreds of years. Hillsides covered in tumbledown houses and a mix of baroque and neoclassical buildings, including cathedrals and palaces, make up Lisbon’s skyline. The city is a combination of old and new, with beautiful modern buildings constructed near renovated historical landmarks and ruins.
Dolce CampoReal Lisboa, Torres Vedras is approximately a 30-minute journey from Lisbon Portela Airport.
Taxis are available outside the airport, but we would strongly recommend you pre-book your airport transfer with one of the many private transfer companies that are available. The Dolce CampoReal Lisboa is located outside of the city zone and a pre-booked transfer will be a cheaper option than a taxi taken from the airport taxi rank.
Uber also operate in and around Lisbon and there are other Portuguese taxi-hailing apps such as Bolt, MyTaxi, TaxisLisboa and Coop Taxis, all offering reasonable rates.
Should you wish to pre-book a taxi transfer from the airport, details will be released soon for our recommended transfer suppliers.
Transportation is the sole responsibility of the delegate. Please ensure you conduct your own research and double check your booking details ahead of your arrival. Fusion Conferences are unable to assist with or confirm transportation bookings due to insurance limitations. Thank you for your understanding.
There are various on-site activities available. These include:
- Indoor and 2 outdoor swimming pools
- Fitness centre, available 24h
- Tennis courts
- Donald Steel designed Golf Course – 18 holes Par 72
- Mandalay Wellness & Spa with 7 treatment rooms
- Kids Club – The hotel will provide details of daily activities for children
- Center “Clube Aventura” for outdoor activities such as Giant Balls, Aquaball, Stand Up Paddle, Archery, Slackline, Water Slide
**Please note, there may be a charge to participate in some of the above activities.
Should you have time to venture off-site, the Oeste Region and Torres Vedras have a distinctive cultural heritage, rich history, 20 km of coastal area, and a commitment to environmental awareness, accessibility and biodiversity. Below are a few suggestions:
- Monastery of Alcobaça, a UNESCO World Heritage site
- Historical route of the lines of Torres Vedras
- Day trip to Óbidos
- Royal Palace and Convent of Mafra
- Tapada Nacional de Mafra
- Mountain biking along the Santa Cruz to Torres Vedras Loop
- Birdwatching at the Tajus Estuary Nature Reserve
- Jeep tours in and around Torres Verdras
If you are interested in this meeting but not yet ready to register, you can sign up for updates here and our team will keep you updated regarding deadline reminders and grant opportunities relating to this meeting only.
Conference Manager
Rosie Johnson
As a family run business, our dedication runs deep. We’re committed to each other and, even more so, to every attendee’s experience, delivering a level of care and passion that’s truly unmatched.