08 Mar - 11 Mar 2017
Cancun, Mexico
David Ornitz
Washington University
Saverio Bellusci
Justus-Liebig-Universitaet Giessen, ECCPS
Early Bird - Expired • Talk Submission - Expired • Poster Submission - Expired • Registration & Payment Deadline - Expired
This second Fusion conference on Fibroblasts Growth Factors in Development and Repair took place in Cancun Mexico, from March 8 through March 11, 2017. The meeting was chaired again by Prof. David Ornitz (Washington University, St Louis, USA) and Prof. Saverio Bellusci (Justus Liebig University, Giessen, Germany).
The invited Faculty, which presented state of the art data, included Dr. Richard Grose (Queen Mary University of London), Dr. Stijn de Langhe (University of Alabama Birmingham), Dr. Mohammad Hajihosseini (University of East Anglia), Dr. Laurence Legeai-Mallet (Imagine Institute-Inserm U1163), Dr. Bradley Olwin (University of Colorado Boulder), Dr. Dina Ron (Technion - Israel Institute of Technology), Dr. Michael Simons (Yale University), Dr. Philippe Soriano (The Mount Sinai Hospital), Dr. Sabine Werner (ETH, Zurich), Dr. Xin Sun (University of Calif, San Diego), Dr. Fen Wang (Texas A&M) and Dr. Jin-San Zhang (Mayo Clinic).
We also recruited other speakers, both junior, mid-level, and senior scientists from the submitted abstracts. We had a good ratio of speakers both in terms of gender and seniority, with the priority given to junior to mid-level scientists.
Contrarily to the first meeting, which was organized on a relatively short notice, the chairs had plenty of time to organize this meeting as well as to do fund raising, with most of the money coming from biotech companies, scientific publishing companies and academic institutions. This allowed us to provide substantial funding for travel awards to most of the students, postdocs, and junior faculty attending to this meeting. The program set by the chairs attracted participants from many countries with various scientific interest. The participants at this meeting primarily worked in the field of FGFs in cancer, neurobiology, regeneration and disease, organogenesis, musculoskeletal and vascular development. This meeting allowed networking and cross fertilization of ideas between overlapping but related fields of research.
The conference venue, the fusion staff and the fantastic weather at this time of the year permitted us to conduct the meeting in a stress-free atmosphere which was very helpful to allow the field to advance. Most of the attendees participated to the discussion and plenty of time was available for networking and setting up collaborations. The poster presentations were also actively attended and provided an additional platform for discussion and collaboration.
In conclusion, this Fusion meeting was very successful and the attendants decided to organize another meeting in 2019 which will be chaired by Dr. Sabine Werner and Dr. Brad Olwin.
The major goal of this Fusion Conference is to bring together in a single forum the diverse group of researchers who study fibroblast growth factor (FGF) signaling. This will provide a unique opportunity to discuss new results and to target future research areas.
Zamal Ahmed (The University of Texas MD Anderson Cancer Center)
Stijn de Langhe (National Jewish Health)
Masatoshi Fujiwara (Ribomic)
Mitchell Goldfarb (Hunter College)
Richard Grose (Queen Mary University of London)
Robert Guzy (The University of Chicago)
Mohammad Hajihosseini (University of East Anglia)
Stacey House (Washington University)
Sung-Ho Huh (University of Nebraska Medical Center)
Marja Hurley (UConn Health)
Fernanda Laezza (UTMB Health)
Laurence Legeai-Mallet (Imagine Institute-Inserm U1163)
Mark Lewandoski (NCI)
Helen Makarenkova (The Scripps Research Institute)
Suzanne Mansour (The University of Utah)
Ivor Mason (King's College London)
Nora M. Navone (MD Anderson Cancer Center)
Victor Nurcombe (IMB)
Bradley Olwin (University of Colorado Boulder)
Dina Ron (Technion - Israel Institute of Technology)
Michael Seckl (Imperial College London)
Michael Simons (Yale University)
Philippe Soriano (Icahn School of Medicine at Mt. Sinai)
Jeffrey Stavenhagen (Therachon)
Xin Sun (University of Wisconsin–Madison)
Jerry Turnbull (University of Liverpool)
Hisashi Umemori (Harvard Medical School)
Fen Wang (Texas A&M)
David Warburton (University of Southern California)
Sabine Werner (ETH Zurich Institute of Molecular Health Sciences)
Zipora Yablonka-Reuveni (University of Washington)
Avner Yayon (ProCore Bio Med)
Jin-San Zhang (Mayo Clinic)
Xin Zhang (Columbia University)
Reflecting the pleiotropic functions of FGF signaling in human biology, FGF researchers encompass a wide range of scientific disciplines, including structural biologists, biochemists, cell biologists, endocrinologists, developmental biologists, geneticists, pharmacologists and clinicians.
David Ornitz
Professor, Washington University
Saverio Bellusci
Chair for Lung Matrix Remodeling, Justus-Liebig-Universitaet Giessen, ECCPS
Richard Grose
Reader, Queen Mary, University of London
Marja Hurley
Professor of Medicine, UCONN Health, School of Medicine
Suzanne Mansour
Professor, University of Utah
Stijn De Langhe
Professor, Mayo Cinic, Rochester
Xin Sun
Professor, University of California, San Diego.
Helen Makarenkova
Assistant Professor, The Scripps Research Institute
Zamal Ahmed
Assistant Professor, MD Anderson Cancer Center
Mitchell Goldfarb
Professor, Hunter College
Sabine Werner
Prof. Dr., ETH Zurich Institute of Molecular Health Sciences
Fen Wang
Professor, Texas A&M University
Fernanda Laezza
Associate Professor, UTMB
Xin Zhang
Associate Professor, Columbia University
Michael Seckl
Professor of Molecular Oncology, Imperial College London
Robert Guzy
Assistant Professor, The University of Chicago
Mark Lewandoski
Senior Investigator, NCI, NIH
David Warburton
Jodi S. Ogden - VP, Research Administration, Children's Hospital Los Angeles
Mohammad K Hajihosseini
Senior Lecturer in Neuroscience, University of East Anglia
Sung-Ho Huh
Assistant Professor, University of Nebraska Medical Center
Stacey House
Research Director in Emergency Medicine, Washington University in St. Louis
Masatoshi Fujiwara
Board Director, Research & Development Division, RIBOMIC Inc.
Jeffrey Stavenhagen
Vice president, Therachon
Avner Yayon
CEO, Procore Ltd.
Dina Ron
Faculty Member/Lab Chief, Technion, Israel Instititute of Technology
NORA NAVONE
PROFESSOR, UT MD ANDERSON CANCER CENTER
Jerry Turnbull
Johnston Professor of Biochemistry, University of Liverpool
Philippe Soriano
Professor, Icahn School of Medicine at Mt. Sinai
Hisashi Umemori
Associate Professor, Harvard Medical School
Laurence Legeai-Mallet
Director of Research, Imagine Institute-Inserm U1163
Michael Simons
Professor, Yale University
Bradley Olwin
Professor, University of Colorado
Zipora Yablonka-Reuveni
Professor, University of Washington School of Medicine
Jin-San Zhang
Professor, Wenzhou Medical University
WEDNESDAY 8TH MARCH 2017 |
||
14:00 – 14:45 |
Registration |
|
14:00 – 14:45 |
Welcome Lunch *Kalmia Buffet Restaurant* |
|
14:45 – 15:00 |
Opening Comments |
|
CANCER |
||
15:00 – 15:25 |
Richard Grose |
UNDERSTANDING DRUG RESISTANCE IN FGFR DRIVEN CANCER |
15:25 – 15:50 |
Fen Wang |
FGF SIGNALING IN PROSTATE CANCER PROGRESSION |
15:50 – 16:15 |
Nora Navone |
TARGETING THE BONE COMPARTMENT IN METASTATIC PROSTATE CANCER |
16:15 – 16:35 |
Zamal Ahmed |
ROLE OF GRB2 IN FGFR2 SIGNALING AND BEYOND |
16:35 – 17:00 |
Jin-San Zhang |
FGF 2 PROTECTS AGAINST RENAL ISCHEMIA/REPERFUSION INJURY BY ATTENUATING MITOCHONDRIAL DAMAGE AND PROINFLAMMATORY SIGNALING |
17:00 – 17:30 |
Refreshments & Poster Viewing |
|
BONE AND CARTILAGE |
||
17:30 – 17:50 |
Marja Hurley |
FGF2 ISOFORMS AND OSTEOARTHRITIS |
17:50 – 18:10 |
David Ornitz |
FIBROBLAST GROWTH FACTORS: CRITICAL REGULATORS OF OSTEOGENIC AND CHONDROGENIC GROWTH PROGRAMS |
18:10 – 18:30 |
Laurence Legeai-Mallet |
FGFR3 REGULATES PRIMARY CILIA ELONGATION THROUGH AUTOPHAGY |
18:30 – 18:50 |
Jeffrey Stravenhagen |
DEVELOPMENT OF A NOVEL BIOLOGIC FOR THE TREATMENT OF ACHONDROPLASIA |
18:50 – 19:10 |
Avner Yayon |
RECEPTOR SELECTIVE, HEPARAN SULFATE DEPENDENT, ENGINEERED VARIANTS OF FGF18 FOR THE TREATMENT OF DAMAGE INDUCED OSTEOARTHRITIS |
19:10 |
Dinner at Leisure |
THURSDAY 9TH MARCH 2017 |
||
07:00 – 08:30 |
Breakfast *Kalmia Buffet Restaurant* |
|
MUSCLE, SKIN AND VASCULATURE |
||
08:30 – 08:50 |
Stacey House |
ROLE OF FGF9 AND FGF16 IN ACUTE CARDIAC INJURY AND REPAIR |
08:50 – 09:15 |
Michael Simons |
FGF-DEPENDENT CONTROL OF VASCULAR METABOLISM |
09:15 – 09:40 |
Bradley Olwin |
REGULATING SKELETAL MUSCLE REGENERATION AND SIZE BY DISRUPTING SATELLITE CELL TERMINAL DIFFERENTIATION |
09:40 – 10:20 |
Refreshments & Group Photo |
|
10:20 – 10:45 |
Sabine Werner |
ROLE AND MECHANISM OF ACTION OF FIBROBLAST GROWTH FACTORS IN INFLAMMATORY SKIN DISEASE |
10:45 – 11:10 |
Zipora Yablonka-Reuveni |
THE STATUS OF FGFRS AND THEIR KLOTHO CO-RECEPTORS IN SKELETAL MUSCLE MYOGENESIS AND FIBRO/ADIPOGENESIS |
11:10 – 11:30 |
Elissavet Kardami |
FGF-2 EXERTS DIRECT PROTECTIVE OR DESTRUCTIVE EFFECTS ON CARDIAC MITOCHONDRIA, IN AN ISOFORM-SPECIFIC MANNER, MEDIATED BY A MITOCHONDRIAL RECEPTOR |
11:30 – 11:50 |
Peter Cattini |
FGF-16 AND ACUTE DOXORUBICIN CARDIOTOXICITY: AN EARLY TARGET FOR EARLY PROTECTION |
11:50 – 16:30 |
Lunch at Leisure & Free Time |
|
SIGNALING |
||
16:30 – 16:55 |
Philippe Soriano |
FGF SIGNALING PATHWAYS IN MOUSE DEVELOPMENT |
16:55 – 17:20 |
Jerry Turnbull |
TUNING FGF SIGNALING WITH DEFINED HEPARAN SULFATE SACCHARIDES |
17:20 – 17:45 |
Dina Ron |
DISSECTING THE ROLE OF THE TUMOR SUPPRESSOR SEF: FROM IN-VITRO TO IN-VIVO |
17:45 – 18:10 |
Michael Seckl |
FGF-2 PROSURVIVAL SIGNALLING AND THE USE OF AN FGFR INHIBITOR TO REVERSE RESISTANCE TO THERAPY IN CANCER: FROM BENCH TO BEDSIDE |
POSTER TALKS |
||
18:10 – 18:20 |
Malgorzata Zakrzewska |
TRANSLOCATED FGF1 AND FGF2 PROTECT THE CELL AGAINST APOPTOSIS |
18:20 – 18:30 |
Stephanie Kainrath |
LIGHT INDUCED INHIBITION OF AN OPTOGENETIC FGFR1 MIMICKING CONSTITUTIVE ACTIVITY |
18:30 – 18:40 |
David Dolivo |
FIBROBLAST GROWTH FACTOR 2 INHIBITS FIBROBLAST ACTIVATION AND ATTENUATES MYOFIBROBLAST PHENOTYPES IN HUMAN DERMAL FIBROBLASTS |
18:40 – 19:40 |
Poster Session I & Refreshments |
|
19:40 |
Dinner at Leisure |
FRIDAY 10TH MARCH 2017 |
||
07:00 – 08:30 |
Breakfast *Kalmia Buffet Restaurant* |
|
LUNG |
||
08:30 – 08:40 |
Navid Koleini |
FIBROBLAST GROWTH FACTOR-2 PROTECTION FROM CANCER DRUG CARDIOTOXCITY IS MEDIATED BY THE MTOR/NRF2/HEMOXYGENASE-1 PATHWAY |
08:40 – 08:50 |
Stefan Hadzic |
THE ROLE OF FGF10 IN THE PATHOGENESIS OF CIGARETTE SMOKE-INDUCED EMPHYSEMA AND PULMONARY HYPERTENSION |
08:50 – 09:15 |
Cho-Ming Chao |
ROLE OF FGF10 SIGNALLING IN ALVEOLAR EPITHELIAL LINEAGE FORMATION |
09:15 – 09:40 |
Xin Sun |
FGF FUNCTION IN LUNG MATURATION |
09:40 – 10:05 |
David Warburton |
SOME NEW IDEAS REGARDING THE POTENTIAL FUNCTION OF FGF SIGNALING IN DEVELOPMENT OF THE GAS DIFFUSION SURFACES OF THE LUNG |
10:05 – 10:30 |
Robert Guzy |
MESENCHYME-SPECIFIC FGF SIGNALING IN PULMONARY FIBROSIS |
10:30 – 11:00 |
Refreshments & Poster Viewing |
|
11:00 – 11:25 |
Stijn de Langhe |
EPITHELIAL YAP TUNES FGF10 EXPRESSION IN THE STROMAL NICHE |
11:25 – 11:50 |
Xin Zhang |
NEURAL CREST FGF SIGNALING CONTROLS LACRIMAL GLAND DEVELOPMENT |
POSTER TALKS |
||
11:50 – 12:00 |
Andrew Hagan |
FGF18 SIGNALING IN POSTNATAL ALVEOLOGENESIS |
12:00 – 12:10 |
Amit Shrestha |
MIR-142 REGULATES ALVEOLAR LINEAGE FORMATION DURING LUNG DEVELOPMENT |
12:10 – 12:25 |
Discussion on the future of the FGF series |
|
12:25 – 16:30 |
Lunch at Leisure & Free Time |
|
DEVELOPMENT |
||
16:30 – 16:55 |
Helen Makarenkova |
FGF10 REGULATES ADULT LACRIMAL GLAND STEM CELL DYNAMIC AND HIERARCHY |
16:55 – 17:20 |
Mohammad Hajihosseini |
NEW INSIGHTS INTO THE EXPRESSION AND FUNCTIONS OF FGF10 DURING MOUSE LIMB DEVELOPMENT |
17:20 – 17:45 |
Mark Lewandoski |
THE ROLE OF FGF ACTIVITY DURING SOMITOGENESIS AND EXTENSION OF THE VERTEBRATE AXIS |
PHARMACOLOGY |
||
17:45 – 18:10 |
Masatoshi Fujiwara |
DIVERGENT ROLES OF FGF2 IN DISEASE PROGRESSION: MULTIACTIONS OF ANTI-FGF2 APTAMER |
18:10 – 18:25 |
Jin-San Zhang |
TENRYPHARM FROM CHINA, WITH ACIDIC FGF FOR WOUND HEALING USE |
18:25 – 19:25 |
Poster Session II & Refreshments |
|
20:00 |
*Gala Dinner & Poster Awards* |
SATURDAY 11TH MARCH 2017 |
||
07:00 – 08:30 |
Breakfast *Kalmia Buffet Restaurant* |
|
NEUROBIOLOGY AND INTRACELLULAR FGFS |
||
08:30 – 08:55 |
Suzanne Mansour |
FGFR2B LIGANDS IN HEARING |
08:55 – 09:20 |
Ivor Mason |
FGF REGULATION OF CONNECTIVITY IN THE DEVELOPING VERTEBRATE BRAIN |
09:20 – 09:45 |
Sung-Ho Huh |
ADMINISTRATION OF FGF9 IN VIVO RESCUES LOSS OF LATERAL COMPARTMENT OF ORGAN OF CORTI CUASED BY DELETION OF FGF20 |
09:45 – 10:10 |
Mitchell Goldfarb |
FHF MODULATION OF SODIUM CHANNELS IN BRAIN AND HEART: NORMAL AND PATHOLOGICAL MECHANISMS |
10:10 – 10:40 |
Refreshments |
|
10:40 – 11:05 |
Fernanda Laezza |
DEVELOPING FGF14-BASED PROBES TARGETING NEURONAL EXCITABILITY |
11:05 – 11:30 |
Hisashi Umemori |
THE FGF22–IGF2 SIGNALING REGULATES SYNAPSE STABILIZATION AND AFFECTIVE BEHAVIOR |
11:30 – 11:50 |
Daniel Sinden |
FGF13 REGULATES OBESITY IN MICE |
11:50 – 12:00 |
Closing Comments |
Interested in sponsoring this conference?
Contact usFiesta Americana Condesa
This stylish hotel features contemporary Mexican architecture, including one of the largest and most impressive thatched-roof "palapas" in the entire country. There are cultural activities, arts and crafts and sports programs to keep you constantly entertained, plus time to relax and enjoy the Mayan culture, soak up the Caribbean sunshine and revel in the international ambiance that settles in after the sun goes down.
Throughout your stay delegates will enjoy a full meal plan, inclusive of beverages. Take your pick from the aromatic Asian delights at Kaumbu, traditional fare at El Mexicano, delicious international cuisine at Kalmia Buffet or perhaps sample the sumptuous Italian dishes at Rosato. There are also several other dining opportunities such as the Cevichería, Pizzeria, Sushi Corner, pool and lounge bar areas. The Gala Night with either a Mayan or Caribbean theme takes place on the third evening of the conference with a mouth-watering feast of local cuisine, an open bar and amazing local entertainment. We welcome all delegates and their accompanying persons to the Gala Night – a truly fun filled night not to be missed!
Hotel Facilities
The Fiesta Americana Condesa, Cancun is the 2015 Winner of the Trip Advisor Certificate of Excellence and also received the Travellers Choice Award in 2014.
The remains of ancient Mayan cities are scattered throughout the Yucatan Peninsula and no trip to Cancun would be complete without a visit to these majestic temples and pyramids set amongst lush tropical vegetation. We will be working very closely with a reputable tour company who will be organising trips to Tulum, Chichen Itza, Coba and Xcaret to name a few, some of which may require a full day. Full day excursions will be arranged pre or post conference and may be on an individual or group booking so we would recommend booking extra nights to extend your stay as early as possible to avoid disappointment should these excursions be of interest to you and/or your party. For further information please contact us.
Venue Rating
★ ★ ★ ★ ★
Currency
US Dollar (USD)
Address
Fiesta Americana Condesa, Blvd.Kukulkán km 16.5 Zona Hotelera, Cancun, 77500 Mexico
Nearest Airport
Cancun International Airport
Cancun is a delightful combination of natural beauty, islands, ecological reserves and white sandy beaches. However, besides sun, sand and sea, this destination also offers an infinite variety of underwater activities to choose from: the diving, snorkelling and fishing here are outstanding and you will find an undersea world packed with tropical fish that live on the second largest barrier reef in the world. Sports enthusiasts might choose one of the many eco-tourism activities, such as cycling or hiking through the tropical forest or kayaking through mangroves, or something a little more adventuresome, like zip lining through the treetops.
Apart from the more well-known ancient Mayan archealogical sites such as Tulum, Cobá and Chichén Itzá you may like to visit the Aktun Chen caverns, voted one of the Top 10 underwater walks by National Geographic described as a truly magical experience.
If you are interested in this meeting but not yet ready to register, you can sign up for updates here and our team will keep you updated regarding deadline reminders and grant opportunities relating to this meeting only.
If you're interested in sponsoring this conference please contact us.
Conference Manager
Jack Peters
As a family run business, our dedication runs deep. We’re committed to each other and, even more so, to every attendee’s experience, delivering a level of care and passion that’s truly unmatched.