Programme
MONDAY 27TH MAY 2019 |
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14:00 – 15:00 |
Registration & Welcome Reception |
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Tumor Metabolism and Cell Intrinsic Pathways |
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15:00 – 15:10 |
Opening Comments |
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15:10 – 15:35 |
Ralph Deberardinis |
METABOLIC REPROGRAMMING IN HUMAN DISEASES |
15:35 – 16:00 |
Cristina Muñoz Pinedo |
CELL-CELL RESPONSES TO STARVATION: INFLAMMATION |
16:00 – 16:25 |
Claudio Mauro |
METABOLITE-MEDIATED REGULATION OF INFLAMMATION |
16:25 – 16:50 |
Shigekazu Nagata |
PHOSPHOLIPID FLIPPASE AND SCRAMBLASE |
16:50 – 17:35 |
Refreshments |
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17:35 – 18:10 |
Poster Presenter Short Teaser Talks |
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18:10 – 18:35 |
Vishva Dixit |
NON - CANONICAL INFLAMMASOME PATHWAY |
18:35 – 19:00 |
Scott Lowe |
RESTORING TUMOR SUPPRESSION IN ADVANCED CANCERS |
19:00 – 19:15 |
Rute Ferreira |
CD9 IDENTIFIES PANCREATIC CANCER STEM CELLS AND MODULATES GLUTAMINE METABOLISM TO FUEL TUMOUR GROWTH |
19:15 – 19:40 |
Gerard Evan |
BUILDING AND KILLING CANCERS |
19:40 |
Group Dinner |
TUESDAY 28TH MAY 2019 |
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07:00 – 08:45 |
Buffet Breakfast at Chulavista |
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Cancer Biology and the Tumor Microenvironment |
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08:45 – 09:10 |
Matthew Albert |
CHEMOTHERAPY INDUCED DNA DAMAGE ENHANCES THE IMMUNOGENICITY OF DYING CELLS |
09:10 – 09:25 |
Tania Løve Aaes |
NECROPTOSIS UNLIKE APOPTOSIS INDUCES IMMUNOGENICITY AGAINST NEO-EPITOPES IN A TUMOR VACCINATION SETTING |
09:25 – 09:50 |
Stephen Tait |
FIRST AMONG EQUALS - MITOCHONDRIAL HETEROGENEITY, CELL DEATH AND CANCER |
09:50 – 10:15 |
Kairbaan Hodivala-Dilke |
SURPRISES FROM TARGETING THE TUMOUR MICROENVIRONMENT |
10:15 – 10:45 |
Refreshments & Poster Viewing |
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10:45 – 11:10 |
Massimo Santoro |
METABOLIC SIGNALING IN ANGIOGENESIS AND CANCER PROGRESSION |
11:10 – 11:35 |
Shoukat Dedhar |
HYPOXIA AND ACIDOSIS MEDIATED STRESS SIGNALING: TARGETING CARBONIC ANHYDRASE IX/XII |
11:35 – 17:30 |
Lunch at Leisure & Free Time |
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12:00 – 17:00 |
Group Snorkeling Trip (sign-ups required in advance) |
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Translational Control Mechanisms and Oncogenesis |
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17:30 – 17:55 |
Nahum Sonenberg |
TRANSLATIONAL CONTROL OF CANCER BY EIF4E VIA THE PI3K/MTOR AND RAS/MAPK PATHWAYS |
17:55 – 18:20 |
Davide Ruggero |
TRANSLATING THE CANCER GENOME ONE CODON AT A TIME AND ITS THERAPEUTIC IMPLICATIONS |
18:20 – 18:45 |
Poul Sorensen |
TUMOR CELLS EXPLOIT THE MICROENVIRONMENTAL STRESS RESPONSE TO ENHANCE METASTATIC CAPACITY |
18:45 – 19:30 |
Refreshments & Poster Viewing |
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19:30 – 19:55 |
Lynne-Marie Postovit |
TRANSLATIONAL CONTROL OF BREAST CANCER PLASTICITY |
19:55 – 20:20 |
Ivan Topirisovic |
TRANSLATIONAL REGULATION OF METABOLIC PLASTICITY |
20:20 |
Dinner at Leisure |
WEDNESDAY 29TH MAY 2019 |
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07:00 – 09:00 |
Buffet Breakfast at Chulavista |
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Cell Death and Inflammation Signaling I |
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09:00 – 09:25 |
Francis Chan |
PARADOXICAL ROLES OF RIP KINASES IN INJURY-INDUCED INFLAMMATION |
09:25 – 09:50 |
Alessandro Annibaldi |
CHECKPOINTS IN TNF-INDUCED CELL DEATH |
09:50 – 10:15 |
Philipp Jost |
TNF SIGNALING CONTROLS RIP KINASE-DEPENDENT CELL DEATH IN LEUKEMIA |
10:15 – 10:40 |
Mathieu Bertrand |
REGULATION OF RIPK1-DEPENDENT CELL DEATH IN MODELS OF INFECTION AND INFLAMMATION |
10:40 – 11:25 |
Group Photo, Refreshments & Poster Viewing |
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Cell Death and Inflammation Signaling II |
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11:25 – 11:50 |
Henning Walczak |
CELL DEATH-INDUCED INFLAMMATION – TNF AND BEYOND |
11:50 – 12:05 |
Diego de Miguel |
A NEW KINASE-MEDIATED CHECKPOINT IN TNFR1 SIGNALLING |
12:05 – 12:30 |
Andrew Oberst |
NECROPTOSIS WITHOUT CELL DEATH: HOW THE RIP KINASES CONTROL VIRAL INFECTION IN THE BRAIN |
12:30 – 12:35 |
Ronny Schmidt |
USP11 KNOCK OUT, IN-DEPTH UBIQUITINATION AND PROTEIN EXPRESSION LEVEL PROFILING |
12:35 – 16:30 |
Lunch at Leisure & Free Time |
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Cell Death and Inflammation Signaling II - Continued |
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16:30 – 16:55 |
Najoua Lalaoui |
MUTATIONS THAT PREVENT CASPASE-8 CLEAVAGE OF RIPK1 CAUSE INFLAMMATION IN HUMANS AND MOUSE |
Necroptosis, Ferroptosis and Beyond I |
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16:55 – 17:20 |
Scott Dixon |
A NOVEL MECHANISM OF NON-APOPTOTIC LIPOTOXICITY |
17:20 – 17:45 |
EMBO YOUNG INVESTIGATOR LECTURE Ana García-Sáez |
STRUCTURAL REARRANGEMENTS DURING MLKL ACTIVATION |
17:45 – 18:00 |
David Armenta |
INVESTIGATING MACROPINOCYTOSIS AS A MEANS TO PREVENT FERROPTOSIS |
18:00 – 18:45 |
Refreshments & Poster Viewing |
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18:45 – 19:10 |
Tom Vanden Berghe |
FERROPTOSIS AND INFLAMMATION RESEARCH IN CRITICAL ILLNESS |
19:10 – 19:25 |
Marcos Perez Washington State University |
DIETARY FATTY ACIDS INDUCE FERROPTOSIS IN THE C. ELEGANS GERM LINE |
19:25 – 19:40 |
Samya Van Coillie |
NOVEL THIRD-GENERATION FERROSTATINS PROTECT AGAINST ACUTE IRON POISONING-INDUCED ORGAN INJURY |
20:00 |
Gala Dinner |
THURSDAY 30TH MAY 2019 |
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07:00 – 09:30 |
Buffet Breakfast at Chulavista |
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Necroptosis, Ferroptosis and Beyond II |
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09:30 – 09:55 |
Petr Broz |
GBPS AND CASPASE-4 ASSEMBLE THE NON-CANONICAL INFLAMMASOME AT THE OUTER MEMBRANE OF CYTOSOLIC BACTERIA |
09:55 – 10:20 |
Christine Watson |
CELL DEATH INITIATES DYNAMIC ARCHITECTURAL CHANGES IN THE EPITHELIUM AND ASSOCIATED IMMUNE CELLS AND VASCULATURE DURING MAMMARY GLAND INVOLUTION |
10:20 – 10:45 |
Andreas Linkermann |
REGULATED NECROSIS IN ISCHEMIC TISSUES |
10:45 – 11:10 |
Mahvash Tavassoli |
TUMOUR-DERIVED EGFR-CONTAINING EXOSOMES MODULATE TUMOUR HYPOXIA TO INFLUENCE RADIATION-INDUCED CELL DEATH IN HEAD AND NECK CANCERS |
11:10 – 11:25 |
Martin Aichinger |
TARGETING IAP IN CANCER: FROM CELL DEATH INDUCTION TO IMMUNE CELL ACTIVATION |
11:25 – 11:35 |
Closing Comments |
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11:35 |
Refreshments |