Programme
THURSDAY 20TH FEBRUARY |
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13:00 – 14:00 |
Student Networking Lunch |
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15:20 – 16:20 |
Registration & Welcome Reception |
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Transcription |
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16:20 – 16:30 |
Opening Comments |
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16:30 – 16:55 |
Achillefs Kapanidis |
DISSECTING TRANSCRIPTION MECHANISMS VIA REAL-TIME IMAGING OF RNA POLYMERASE CONFORMATIONAL CHANGES |
16:55 – 17:10 |
Emiel Visser |
OBSERVING SINGLE MOLECULE PROTEIN-DNA INTERACTIONS AND DNA TRANSCRIPTION IN-VITRO USING TETHERED PARTICLE MOTION |
17:10 – 17:35 |
Ibrahim Cisse |
SUPER-RESOLUTION IMAGING OF TRANSCRIPTION IN LIVE MAMMALIAN CELLS |
17:35 – 18:20 |
Refreshments |
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18:20 – 18:35 |
Neil Kad |
THE TFIIH COMPONENTS P44/P62 ACT AS A DAMAGE SENSOR DURING NUCLEOTIDE EXCISION REPAIR |
18:35 – 19:00 |
Alexandros Pertsinidis |
SINGLE-MOLECULE STUDIES OF TRANSCRIPTION MECHANISMS |
19:00 – 19:15 |
Huan Zheng |
UNDERSTANDING THE CELL-SIZE REGULATION OF TRANSCRIPTION IN LIVE-YEAST USING SINGLE-MOLECULE TECHNIQUES |
19:15 – 19:30 |
Harshad Ghodke |
MOLECULAR COUPLING BETWEEN TRANSCRIPTION AND DNA REPAIR MACHINERY IN LIVE CELLS DURING TRANSCRIPTIONAL STRESS |
20:00 |
Dinner |
FRIDAY 21ST FEBRUARY |
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07:00 – 09:00 |
Breakfast at Leisure |
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DNA Repair |
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09:00 – 09:35 |
Vincent Croquette |
KINETIC STUDIES OF DEAD AND DEAH HELICASES AND THEIR COFACTORS IN SINGLE MOLECULE ASSAY |
09:35 – 09:50 |
Sunbok Jang |
WATCHING COOPERATIVE INTERACTIONS BETWEEN BASE AND NUCLEOTIDE EXCISION REPAIR PROTEINS |
09:50 – 10:25 |
Dorothy Erie |
INTEGRATIVE SINGLE-MOLECULE STUDIES OF DNA MISMATCH REPAIR INIATION |
10:25 – 10:50 |
Roberto Galletto |
ROLE OF PIF1-HELICASES AT HARD-TO-REPLICATE SITES |
10:50 – 11:15 |
Kevin Raney |
TRANSLOCATION AND DNA UNWINDING ACTIVITIES OF PIF1 FAMILY HELICASES |
11:15 – 12:50 |
Poster Session |
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12:50 – 16:50 |
Lunch at Leisure & Free Time |
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Recombination |
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16:50 – 17:25 |
Maria Spies |
MOLECULAR CHOREOGRAPHY OF THE RPA-DNA-RAD52 COMPLEX DURING DNA REPLICATION, RECOMBINATION AND REPAIR |
17:25 – 17:50 |
Ilya Finkelstein |
COHESIN ORGANIZES THE GENOME VIA LOOP EXTRUSION |
17:50 – 18:05 |
Alexandra Moores |
INVESTIGATING BACTERIAL NUCLEOTIDE EXCISION REPAIR IN MAINTAINING THE INTEGRITY OF REPLICATION FORKS USING SINGLE MOLECULE LIVE CELL IMAGING |
18:05 – 18:50 |
Refreshments & Poster Viewing |
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18:50 – 19:15 |
Steve Kowalczykowski |
WIN, LOOSE, OR DRAW: IMAGING ENCOUNTERS OF INDIVIDUAL MOTOR PROTEINS WITH NUCLEOSOME ARRAYS |
19:15 – 19:40 |
Gijs Wuite |
SINGLE MOLECULE MANIPULATION AND IMAGING OF COMPLEX DNA-PROTEIN TRANSACTIONS |
19:40 – 20:05 |
Keir Neuman |
HOMOLOGY SENSING VIA NON-LINEAR AMPLIFICATION OF SEQUENCE DEPENDENT PAUSING BY RECQ HELICASE |
20:30 |
Dinner |
SATURDAY 22ND FEBRUARY |
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07:00 – 09:00 |
Breakfast at Leisure |
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Chromosome Dynamics I |
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09:00 – 09:35 |
Anton van Oijen |
SINGLE-MOLECULE STUDIES OF EUKARYOTIC DNA REPLICATION |
09:35 – 09:50 |
Vlad-Stefan Raducanu |
ON DEMAND FLUORESCENCE MODULATION (ENHANCEMENT, QUENCHING OR NO EFFECT) FOR STUDYING PROTEIN-DNA INTERACTIONS |
09:50 – 10:15 |
Xiaojun Ren |
VISUALIZATION OF EPIGENETIC PcG COMPLEXES BY USING LIVE-CELL SINGLE-MOLECULE IMAGING |
10:15 – 11:00 |
Group Photo, Refreshments & Poster Viewing |
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11:00 – 11:25 |
Kiyoshi Mizuuchi |
TWO TYPES OF ParA/B/S PLASMID/CHROMOSOME PARTITION SYSTEMS IN BACTERIA: TWO DIFFERENT PARTITION COMPLEX ARCHITECTURES, A COMMON MECHANISM? |
11:25 – 11:50 |
David Sherratt |
ORGANIZATION OF THE ESCHERICHIA COLI CHROMOSOME BY A MukBEF AXIAL CORE |
11:50 – 12:05 |
Celia Viridiana Lopez |
STUDYING DNaA FUNCTION IN VIVO AT A SINGLE-MOLECULE LEVEL |
12:05 – 16:25 |
Lunch at Leisure & Free Time |
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Chromosome dynamics II |
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16:25 – 16:50 |
Jie Xiao |
SPATIAL ORGANIZATION OF TRANSCRIPTION AND CHROMOSOME |
16:50 – 17:05 |
Gurleen Kaur |
ENZYME DYNAMICS DURING LESION BYPASS AT THE E. COLI REPLICATION FORK |
17:05 – 17:30 |
Johan Elf |
LIVE CELL IMAGING OF DOUBLE STRANDED BREAK REPAIR REVEALS FAST HOMOLOGY SEARCH |
17:30 – 17:45 |
Yujing Ouyang |
DNA REPLICATION FORK ARREST BY ESCHERICHIA COLI TUS-TER INVOLVES MECHANISMS THAT ARE INDEPENDENT OF THE C6-MOUSETRAP MODEL |
17:45 – 18:30 |
Refreshments & Poster Viewing |
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18:30 – 18:55 |
Rogelio Hernandez Tamayo |
UNDERSTANDING PROTEIN MOBILITY IN BACILLUS SUBTILIS BY TRACKING SINGLE MOLECULES |
18:55 – 19:20 |
Tatiana Karpova |
SINGLE-MOLECULE STUDIES OF TRANSCRIPTION OF CUP1 LOCUS IN YEAST SACCHAROMYCES |
19:20 – 19:45 |
Terence Strick |
Single-molecule analysis of DNA repair and mutagenesis |
19:45 – 20:00 |
Kyle Vrtis |
PASSIVE AND ACTIVE REPLISOME UNLOADING DURING REPLICATION FORK COLLAPSE |
20:00 |
Gala Dinner & Poster Awards |
SUNDAY 23RD FEBRUARY |
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07:00 – 08:30 |
Breakfast at Leisure |
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DNA Replication |
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08:30 – 08:55 |
Samir Hamdan |
BUILDING THE REACTION TIMELINE OF FEN1 DURING LAGGING STRAND DNA SYNTHESIS |
08:55 – 09:20 |
Rodrigo Reyes |
SUBUNIT DYNAMICS IN THE EUKARYOTIC REPLISOME IN LIVE CELLS |
09:20 – 09:45 |
Ralf Seidel |
DISSECTING THE TARGET RECOGNITION BY CRISPR-CAS COMPLEXES USING SINGLE-MOLECULE NANOMECHANICAL MEASUREMENTS |
09:45 – 10:15 |
Refreshments |
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10:15 – 10:40 |
Andrew Robinson |
SINGLE-MOLECULE LIVE-CELL IMAGING REVEALS RECB-DEPENDENT FUNCTION OF DNA POLYMERASE IV IN DOUBLE STRAND BREAK REPAIR |
10:40 – 10:55 |
Karl Duderstadt |
VISUALIZATION OF TRANSCRIPTION-REPLICATION CONFLICTS REVEALS DYNAMIC REPOSITIONING OF MCM2-7 HELICASES PRIOR TO REPLICATION |
10:55 – 11:10 |
Rohit Agarwal |
FLOW MAGNETIC TWEEZERS: IMAGING RARE ENZYMATIC EVENTS WITH SINGLE-MOLECULE PRECISION |
11:10 – 11:20 |
Closing Comments |