Programme
Sunday 9th August 2015 |
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13:00 – 14:30 |
Registration |
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13:30 – 14:30 |
Welcome Lunch (Hyperion Restaurant) |
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Session Title: New Approaches in Biotech and Academia |
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14:30 – 14:45 |
Opening Speech |
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14:45 – 15:45 |
Harren Jhoti Astex Pharmacueticals |
FRAGMENT-BASED DRUG DISCOVERY: A FIFTEEN YEAR (RE-)EVOLUTION |
15:45 – 16:30 |
Andrew Combs Incyte Pharmaceuticals |
INCYTE’S DATA CENTRIC APPROACH TO RESEARCH |
16:30 – 17:15 |
Gerhard Klebe |
FRAGMENT DISCOVERY AND CHARACTERIZATION: WHAT CRYSTALLOGRAPHY, THERMODYNAMICS AND WATER SUGGEST |
17:15 – 18:00 |
Refreshments & Industry Exhibit |
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Session Title: New Approaches in Pharma |
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18:00 – 18:45 |
Martin Stahl |
HOW MANY MOLECULES DOES IT TAKE TO TELL A STORY? CASE STUDIES, LANGUAGE AND AN EPISTEMIC VIEW OF MEDICINAL CHEMISTRY |
18:45 – 19:15 |
George Trainor BioMotiv |
THE HARRINGTON PROJECT: TRAVERSING THE VALLEY OF DEATH |
19:15 – 19:45 |
Trevor Howe External Innovation Johnson & Johnson |
INNOVATION AND COLLABORATION INITIATIVES IN J&J |
19:45 |
Group Dinner (Hyperion Restaurant) & Free Time |
Monday 10th August 2015 |
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07:00 – 08:30 |
Buffet Breakfast (Hyperion Restaurant) |
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Session Title: Natural Products |
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08:30 – 09:15 |
John Beutler National Cancer Institute-NIH |
PROBING NOVEL CANCER BIOLOGY WITH HIGH THROUGHPUT SCREENING OF NATURAL PRODUCTS |
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09:15 – 09:45 |
David Mead |
FUNCTIONAL METAGENOMICS FOR CLONING AND EXPRESSION OF NOVEL SOIL MICROBIAL SECONDARY METABOLITE PATHWAYS |
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09:45 – 10:15 |
Lars Haustedt AnalytiCon Discovery |
NATURAL PRODUCTS AS LIBRARY BLUE PRINTS - STRUCTURE AND FUNCTION |
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10:15 – 10:45 |
Andreas Vilcinkas Univeristy of Gießen |
INSECTS AS A SOURCE OF NOVEL ANTIBIOTICS |
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10:45 – 11:15 |
Refreshments & Industry Exhibit |
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11:15 – 11:45 |
Thomas Högberg |
CHEMICAL AND BIOLOGICAL STUDIES OF INGENOL 3-CARBOXYLATES FOR TREATMENT OF NON-MELANOMA SKIN NEOPLASIA |
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11:45 – 12:15 |
Vicky Steadman |
A ‘GAME CHANGING’ NEW ANTIBIOTIC: THE DISCOVERY OF TEIXOBACTIN |
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12:15 – 16:00 |
Group Lunch (Hyperion Restaurant) & Free Time |
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Session Title: Government and Non-profit Sector in Drug Discovery and Development |
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16:00 – 16:30 |
Christopher Cooper TB Alliance |
TB ALLIANCE DRUG DISCOVERY: HARNESSING GLOBAL RESOURCES TO ADDRESS A GLOBAL DISEASE |
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16:30 – 17:00 |
James Duffy Medicines for Malaria |
CHALLENGES AND OPPORTUNITIES IN ANTIMALARIAL DRUG DISCOVERY |
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17:00 – 17:30 |
Craig Thomas NCATS, NIH |
CHEMICAL BIOLOGY AS A TRANSLATIONAL ENDEAVOR |
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17:30 – 18:00 |
Joseph Salvino |
CX3CR1 CHEMOKINE ANTAGONISTS HALT METASTATIC SPREADING IN ANIMAL MODELS OF METASTASIS |
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18:00 – 18:30 |
Refreshments & Industry Exhibit |
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18:30 – 18:45 |
Barbara Holtz |
AMPLIFYING THE ROLE OF COLLABORATION GLOBALLY FOR NEGLECTED AND COMMERCIAL DISEASE DRUG DISCOVERY |
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18:45 – 19:15 |
Ed Champness |
DATA VISUALIZATION: NEW DIRECTIONS OR JUST FAMILIAR ROUTES? |
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19:15 – 19:45 |
Panel Discussion: Re-inventing drug discovery: Where do things stand today? |
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19:45 |
Group Dinner (Hyperion Restaurant) & Free Time |
Tuesday 11th August 2015 |
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07:00 – 08:30 |
Buffet Breakfast (Hyperion Restaurant) |
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Session Title: Structure, Modeling, and Fragment-based Design |
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08:30 – 09:15 |
Tom Blundell University of Cambridge |
STRUCTURE-GUIDED TARGETING OF PROTEIN-PROTEIN INTERFACES IN CELL REGULATORY SYSTEMS |
09:15 – 09:45 |
Gregory Warren OpenEye Scientific Software |
UNDERSTANDING THE ESSENTIAL REQUIREMENTS FOR SUCCESS IN STRUCTURE-BASED DESIGN |
09:45 – 10:15 |
Heather A. Carlson University of Michigan |
MIXMD: MAPPING PROTEIN SURFACES TO DISCOVER DRUGGABLE ALLOSTERIC SITES |
10:15 – 10:45 |
Refreshments & Industry Exhibit |
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10:45 – 11:15 |
Chris Murray Astex Pharmacueticals |
EXPLOITING STRUCTURAL DATA TO ACCELERATE FRAGMENT-BASED DRUG DISCOVERY |
11:15 – 11:45 |
Martin Slater Cresset |
IN SILICO DRUG DISCOVERY OUTSIDE THE TRADITIONAL BIG PHARMA MODEL |
11:45 – 16:30 |
Group Lunch (Hyperion Restaurant) & Free Time |
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Session Title: Non-traditional Targets and Approaches |
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16:30 – 17:00 |
Siew Ho |
NUCLEIC ACID MOLECULES IN RESEARCH AND THERAPEUTICS |
17:00 – 17:30 |
Troy Messick |
DRUG DISCOVERY AT THE ACADEMIC/START-UP BIOTECH INTERFACE: DEVELOPMENT OF SMALL MOLECULE INHIBITORS OF EPSTEIN-BARR VIRUS-ASSOCIATED DISEASES |
17:30 – 18:00 |
Roger Tung |
SELECTIVE DEUTERIUM SUBSTITUTION: A BROAD AND EFFICIENT PLATFORM FOR NEW DRUG CREATION |
18:00 – 18:30 |
Jan Hoflack |
NANOCYCLIX PROBE-BASED DRUG DISCOVERY: NEXT GENERATION KINASE INHIBITORS OPENING UP THE UNEXPLORED KINOME |
18:30 – 19:30 |
Poster Session, Cocktails & Industry Exhibit |
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20:00 – 23:00 |
*Gala Night & Group Photo* |
Wednesday 12th August 2015 |
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07:00 – 08:30 |
Buffet Breakfast (Hyperion Restaurant) |
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Session Title: Non-traditional Targets and Approaches |
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08:30 – 09:00 |
Luc Van Hijfte |
NON-COVALENT MASS SPECTROMETRY : AN ESI WAY TO SUPPORT DRUG DISCOVERY |
09:00 – 09:30 |
James Bashkin |
LARGE HAIRPIN POLYAMIDES WITH NEW N-TERMINI: DNA BINDING PROPERTIES AND ACTIVITY AGAINST HIGH-RISK HPVS |
09:30 – 10:15 |
Refreshments & Industry Exhibit |
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10:15 – 10:45 |
Jin Li |
ENCODED MACROCYCLIC LIBRARIES FOR FINDING NOVEL PROTEIN-PROTEIN INTERACTION INHIBITORS |
10:45 – 11:15 |
Kevin Cox Imanova |
REDUCING RISK IN DRUG DEVELOPMENT – THE 3 I’S OF MOLECULAR IMAGING |
11:15 – 11:45 |
Bill Kinney KannaLife Sciences |
THE ARCHITECTURE AND SCIENCE OF VIRTUAL DRUG DISCOVERY IN THE CANNABINOID SPACE |
11:45 – 12:00 |
Closing Remarks |