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Laura Trundle

Laura Trundle

DNA Replication as a Source of DNA Damage

From Molecules to Human Health


30 Sep 2014 - 03 Oct 2014

El Jadida, Morocco

Chairs

Ian Hickson
University of Copenhagen
Oscar Fernandez-Capetillo
Spanish National Cancer Research Centre

Synopsis

The maintenance of genome integrity is critical for the suppression of cancer and premature ageing. Only recently has it become appreciated that DNA replication stress is a crucial driver of genomic instability. The timely progression of replisomes can be disrupted by lesions and secondary structures in the template, by bound proteins and by conflicts with the transcription machinery. A prolonged pause of the replisome then exposes single stranded DNA, which, due to its recombinogenic nature, can lead to genome rearrangements, fragile site expression and cell death. Importantly, some cancers present excessive endogenous levels of replication stress, which can be exploited for their clearance. In this conference, we aim to bring together scientists studying DNA replication and repair, with those interested in how DNA damage can influence cancer and ageing. 

Key Sessions

  • Pathways for repair of damaged replication forks
  • Systems for site-specific perturbation of replication
  • Chromosome fragility caused by difficult-to-replicate loci – sources and roles of DNA repair proteins
  • Replication perturbation as a driver of tumorigenesis and ageing
  • Exploitation of replication defects in cancer treatment

Supported By

Diamond
If you're interested in sponsoring this conference please contact us.

DNA Replication as a Source of DNA Damage

From Molecules to Human Health


30 Sep 2014 - 03 Oct 2014

El Jadida, Morocco

Chairs

Ian Hickson
University of Copenhagen
Oscar Fernandez-Capetillo
Spanish National Cancer Research Centre

Speakers

Plenary Speakers

Josef Jiricny

Professor and Director, Institute of Molecular Cancer Research

Andre Nussenzweig

Branch Chief, LGI, National Institutes of Health

Steve West

Senior Group Leader, Francis Crick Institute

Antony Carr

Director, Genome Damage and Stability Centre

Karlene Cimprich

Professor, Stanford University

Philippe Pasero

Dr, IGH, CNRS UPR 1142

Thanos Halazonetis

Professor, University of Geneva

Camilla Sjögren

Professor, PI, Karolinska Institutet

Michelle Debatisse

Researcher, UMR8200 CNRS

Jiri Lukas

Managing Director, Novo Nordisk Foundation Center for Protein Research

Simon Boulton

Senior Principle Investigator, London Research Institute

Anja Groth

Associate professor, BRIC, University of Copenhagen

Virginia Zakian

Harry C. Wiess Professor in the Life Sciences, Princeton University

George Garinis

Group leader, Institute of Molecular Biology and Biotechnology-FORTH

Madalena Tarsounas

CR-UK Senior Group Leader, The CR-UK/MRC Oxford Institute for Radiation Oncology, University of Oxford

Evi Soutoglou

Group Leader, Genome Damage and Stability Centre, University of Sussex

Junjie Chen

Professor and Chair, The University of Texas MD Anderson Cancer Center

Massimo Lopes

Assistant Professor, University of Zurich

Invited Speakers

Ana Rojas

Head of the Computational Biology and Bioinformatics Group, Institute of Biomedicine of Seville (IBIS)

Claus Sørensen

Dr., University of Copenhagen

Alessandro Vindigni

Associate Professor, Saint Louis University School of Medicine

Dana Branzei

GROUP LEADER, IFOM ETS

Oliver Mortusewicz

Senior Researcher, Science for Life Laboratory / Karolinska Institutet

Xiaolan Zhao

Professor, Memorial Sloan-Kettering Cancer Center

Sophie Polo

PI, Paris Diderot University

Aidan Doherty

Professor of Biochemistry, University of Sussex

Hocine Mankouri

Research Associate Professor, Nordea Center for Healthy Aging

Raimundo Freire

Researcher, Unidad de Investigacion, Hospital Universitario de Canarias

Noel Lowndes

Professor, National University of Ireland Galway

Juan Méndez

Lab Head, Spanish National Cancer Research Centre (CNIO)

Cynthia McMurray

Senior Scientist, Lawrence Berkeley National Laboratory

Supported By

Diamond
If you're interested in sponsoring this conference please contact us.

DNA Replication as a Source of DNA Damage

From Molecules to Human Health


30 Sep 2014 - 03 Oct 2014

El Jadida, Morocco

Chairs

Ian Hickson
University of Copenhagen
Oscar Fernandez-Capetillo
Spanish National Cancer Research Centre

Programme

Tuesday 30th September 2014

08:00 – 12:00

Registration & Reception

 

11:00 – 11:15

Opening  Comments

 

Session Chair: Stephen West

11:15 – 11:40

Virginia Zakian
Princeton University, New Jersey, USA

PROTEOMICS OF BUDDING YEAST TELOMERASE: THE TELOMERASE ASSOCIATED CDC48-NPL4-UFD1 COMPLEX REGULATES EST1 ABUNDANCE AND TELOMERE LENGTH

11:40 – 12:05

John Rouse
University of Dundee, UK

DISSECTING THE ROLES AND REGULATION OF NUCLEASES INVOLVED IN ICL REPAIR

12:05 – 12:20

Andres Lopez-Contreras
CNIO, Spain

A CONSERVED ROLE FOR NUCLEOTIDE BIOSYNTHESIS ON ATR BIOLOGY IN MAMMALS

12:20 – 12:45

Michelle Debatisse
Institut Curie, Paris, France

RESPECTIVE ROLES OF REPLICATION AND TRANSCRIPTION IN COMMON FRAGILE SITE INSTABILITY

12:45 – 13:10

Xiaolan Zhao
Memorial Sloan-Kettering Cancer Center, USA

REGULATION OF GENOME DUPLICATION

13:10 – 16:30

Group Welcome Lunch & Free Time

Session Chair: Virginia A. Zakian

16:30 – 16:55

Junjie Chen
The University of Texas M.D. Anderson Cancer Center, USA

BALANCE BRCA1 AND 53BP1 AT DSB SITES

16:55 – 17:20

Aidan Doherty
University of Sussex, UK

PRIMPOL, A EUKARYOTIC PRIMASE-POLYMERASE INVOLVED IN LESION BYPASS DURING DNA REPLICATION

17:20 – 17:35

Jennifer Cobb
University of Calgary, Canada

THE NUA4 COMPLEX FUNCTIONS ON THE TRANSLESION SYNTHESIS (TLS) PATHWAY DURING DNA POST REPLICATION REPAIR

17:35 – 18:00

Stephen West
London Research Institute, UK

STRUCTURE AND FUNCTION OF THE BRCA2 TUMOUR SUPPRESSOR

18:00 – 18:25

George Garinis
Institute of Molecular Biology and Biotechnology-FORT, Heraklion, Greece

NUCLEOTIDE EXCISION REPAIR: LESSONS FROM THE MOUSE

18:25 – 19:00

Refreshments

Session Chair: John Rouse

19:00 – 19:25

Juan Méndez
Spanish National Cancer Research Centre (CNIO), Madrid, Spain

CONTROL OF DNA RE-REPLICATION IN VIVO: MOUSE MODELS FOR CDC6 AND CDT1 DEREGULATED EXPRESSION

19:25 – 19:50

Ivan Ahel
University of Oxford, UK

STRUCTURE AND CATALYTIC MECHANISM OF ADP-RIBOSYLGLYCOHYDROLASES

19:50 – 20:15

Hocine Mankouri
University of Copenhagen, Denmark

ANALYSIS OF SITE-SPECIFIC REPLICATION PERTURBATION IN YEAST

20:15 – 20:30

Grant Brown
University of Toronto, Canada

SLX4 PROMOTES MEC1 SIGNALING BEHIND DAMAGED DNA REPLICATION FORKS

20:30 – 21:30

Welcome Buffet Dinner Hosted in Pre-function Area

Wednesday 1st October 2014

Session Chair: Simon Boulton

09:00 – 09:25

Noel Lowndes
National University of Ireland Galway, Ireland

ATR ACTIVATES THE S-M CHECKPOINT DURING UNPERTURBED GROWTH TO ENSURE SUFFICIENT REPLICATION PRIOR TO MITOTIC ONSET

09:25 – 09:50

Andre Nussenzweig
National Institutes of Health, Maryland, USA

DNA-DAMAGE INDUCED DIFFERENTIATION OF LEUKEMIC CELLS AS AN ANTI-CANCER BARRIER

09:50 – 10:05

Makoto Nakanishi
Nagoya City University, Japan

NECESSARY AND SUFFICIENT ROLE FOR A MITOSIS SKIP IN SENESCENCE INDUCTION

10:05 – 10:30

Filippo Rosselli
CNRS - Gustave Roussy Institute, France

 

10:30 – 11:00

Refreshments

Session Chair: Antony Carr

11:00 – 11:25

Sophie Polo
Paris Diderot University, France

CHROMATIN LICENSING FOR TRANSCRIPTION RESTART AFTER DNA DAMAGE

11:25 – 11:50

Massimo Lopes
University of Zurich, Switzerland

REMODELLING OF REPLICATION INTERMEDIATES IN FACE OF REPLICATION STRESS

11:50 – 12:05

Vincent Geli
CRCM, France

RPA AND PIF1 HELICASE PREVENT SECONDARY STRUCTURES FORMATION DURING TELOMERE AND HUMAN SUBTELOMERIC MINISATELLITE REPLICATION

12:05 – 12:30

Alessandro Vindigni
Saint Louis University School of Medicine, USA

DNA2 AND WRN COORDINATE REPLICATION RESTART BY PROCESSING REVERSED REPLICATION FORKS

12:30 – 16:30

Group Lunch & Free Time

14:00 – 17:00

Group Tour to El Jadida (optional)

Session Chair: Josef Jiricny

17:00 – 17:25

Karlene Cimprich
Stanford University, USA

MECHANISMS FOR RNA-INDUCED GENOME INSTABILITY

17:25 – 17:50

Madalena Tarsounas
The CR-UK/MRC Oxford Institute for Radiation Oncology, University of Oxford, UK

HIGHLY SPECIFIC KINASE INHIBITORS ENABLE SELECTIVE TARGETING OF BRCA2- DEFICIENT CELLS

17:50 – 18:05

Kara Bernstein
University of Pittsburgh School of Medicine, USA

SUMO-TARGETED UBIQUITIN LIGASES SLX5-SLX8/RNF4 REGULATE RECQ-LIKE HELICASE SGS1/BLM LOCALIZATION IN YEAST AND HUMAN CELLS

18:05 – 18:30

Ana Rojas Mendoza
Institute of Biomedicine of Seville (IBIS), Sevilla, Spain

COMPARATIVE GENOMICS OF DDR: IMPLICATIONS IN DOWSTREAM ANALYSES

18:30 – 18:55

Thanos Halazonetis
University of Geneva, Switzerland

BREAK-INDUCED REPLICATION MEDIATES REPAIR OF COLLAPSED DNA REPLICATION FORKS AND TANDEM DUPLICATIONS IN CANCER CELLS

18:55 – 20:30

Poster Session I & Cocktail Reception

20:30

Beach BBQ Dinner & Free Time

Thursday 2nd October 2014

Session Chair: Ian Hickson

09:00 – 09:25

Cynthia McMurray
Lawrence Berkeley National Laboratory, California, USA

FXS: REPLICATION DEPENDENT BREAKS AT RNA-DNA HYBRIDS

09:25 – 09:50

Simon Boulton
London Research Institute, UK

DNA REPLICATION AND TELOMERE FUNCTIONS OF RTEL1

09:50 – 10:05

Zuzana Storchova
Max Planck Institute of Biochemistry, Germany

ANEUPLOIDY DRIVES GENOMIC INSTABILITY BY GENERATING REPLICATION STRESS

10:05 – 10:30

Claus Sørensen
University of Copenhagen, Denmark

FBH1 HELICASE: PROMOTING DNA DAMAGE CHECKPOINT SIGNALING FROM STALLED REPLICATION FORKS

10:30 – 11:00

Refreshments

Session Chair: Karlene Cimprich

11:00 – 11:25

Philippe Pasero
IGH, CNRS UPR 1142, Montpellier, France

SAMHD1 PROCESSES STALLED FORKS AND PROMOTES REPLICATION RESTART

11:25 – 11:50

Oscar Fernandez-Capetillo
Spanish National Cancer Research Centre (CNIO), Madrid, Spain

TARGETING ONCOGENE-INDUCED REPLICATION STRESS FOR CANCER THERAPY

11:50 – 12:05

Angelos Constantinou
IGH-Institute of Human Genetics, France

EARLY RESPONDERS TO DNA REPLICATION IMPEDIMENTS

12:05 – 12:30

Jiri Lukas
Novo Nordisk Foundation Center for Protein Research, Copenhagen, Denmark

POLY(ADP-RIBOSE)-DEPENDENT ASSEMBLY OF LOW-COMPLEXITY PROTEINS FUNCTIONS AS A ‘MOLECULAR SIEVE’ DURING THE EARLIEST STAGES OF DNA DAMAGE RESPONSE

12:30 – 16:30

Group Lunch & Free Time

Session Chair: Oscar Fernandez-Capetillo

16:30 – 16:55

Antony Carr
Genome Damage and Stability Centre, UK

MECHANISMS OF REPLICATION-ASSOCIATED GENOME REARRANGEMENT

16:55 – 17:20

Anja Groth
BRIC, University of Copenhagen, Denmark

CHROMATIN REPLICATION AND EPIGENOME MAINTENANCE

17:20 – 17:35

Eric Brown
University of Pennsylvania, USA

GENOME-WIDE IDENTIFICATION OF REPLICATION FORK COLLAPSE SITES THROUGH ATR-DEFICIENCY

17:35 – 19:05

Poster Session II

19:05 – 19:30

Meeting of Poster Jury

21:00 – 00:00

*Gala Night, Group Photo & Poster Awards*

Friday 3rd October 2014

Session Chair: Jiri Lukas

09:35 – 10:00

Dana Branzei
Fondazione Ifom, Milan, Italy

VISUALIZATION OF RECOMBINATION–MEDIATED DAMAGE-BYPASS BY TEMPLATE SWITCHING

10:00 – 10:25

Oliver Mortusewicz
Science for Life Laboratory, Stockholm, Sweden

PC4 PROMOTES GENOME STABILITY AND DNA REPAIR THROUGH BINDING OF SSDNA AT DNA DAMAGE SITES

10:25 – 10:50

Camilla Sjögren
Karolinska Institutet, Stockholm, Sweden

CONNECTING CHROMOSOME REPLICATION AND SEGREGATION: DNA TOPOLOGY AND SMC COMPLEXES

10:50 – 11:15

Evi Soutoglou
IGBMC, Illkirch, France

NUCLEAR COMPARTMENTALIZATION AND GENOME INTEGRITY: DIFFERENTIAL REGULATION OF DNA REPAIR AND DNA DAMAGE RESPONSE AT NUCLEAR LAMINA AND NUCLEAR PORES

11:15 – 11:30

Refreshments

11:30 – 11:55

Ian Hickson
University of Copenhagen, Denmark

HOW UNFINISHED BUSINESS FROM S-PHASE IMPACTS ON MITOSIS

11:55 – 12:20

Josef Jiricny
Institute of Molecular Cancer Research, Zurich, Switzerland

A NOVEL INSIGHT INTO THE CONTRIBUTIONS OF PROOFREADING AND MISMATCH REPAIR TO REPLICATION FIDELITY

12:20 – 12:45

Raimundo Freire
Unidad de Investigacion, Hospital Universitario de Canarias, Spain

UBIQUITIN HYDROLASES AS NOVEL REGULATORS OF DNA REPLICATION

12:45

Closing Remarks (Chairs)

13:00

Farewell & Goodbye

Supported By

Diamond
If you're interested in sponsoring this conference please contact us.

DNA Replication as a Source of DNA Damage

From Molecules to Human Health


30 Sep 2014 - 03 Oct 2014

El Jadida, Morocco

Chairs

Ian Hickson
University of Copenhagen
Oscar Fernandez-Capetillo
Spanish National Cancer Research Centre

Prices

Ticket Type Early Bird Full Price
Single
Choose this option if you will be attending the conference alone, or if you will bring accompanying guests that will not attend the meeting.
$1320 $1535
Shared
Choose this option if you wish to share with a colleague who is also attending the conference, or if you wish to be paired with another attendee of the same sex.
$1320 $1535
Student
Choose this option if you are a student. Please note all students will be paired with another attendee of the same sex if a room sharer is not specified. If you wish to have your own room, please register under the Single option.
$1050 $1295
Additional Person
This is the cost for an additional adult or child to join you in the same room, for the entire conference period. Accompanying persons are not permitted access to the conference. If you wish to extend your stay, please see our 'Extra night' prices.

Adult

$790

Child

$165

Extra nights
Prices are per person.

Adult

$209

Child

$35


All registration fees include 3 nights accommodation and meals during the conference period. Exact inclusions are detailed below.

Our Registration Package: What's Included?

Our registration and accompanying person fees are inclusive of the following; 

  • Accommodation for 3 Nights
  • Breakfast Buffet and Fresh Juices
  • Lunch Buffet and 1 Fruit Juice, ½ Still/Sparkling Water, 1 Soda and 1 Tea/Coffee
  • Dinner Buffet and 1 Glass of House Wine, 1 Fruit Juice, ½ Still/Sparkling Water, 1 Soda and 1 Tea/Coffee
  • Complimentary WI-FI in Conference Rooms
  • Complimentary WI-FI in Guest Room
  • Gala Night Entry

Please note accompanying persons are not permitted access to the conference.


Additional nights (per person) are inclusive of the following; 

  • Accommodation for 1 Night
  • Buffet Breakfast

Supported By

Diamond
If you're interested in sponsoring this conference please contact us.

DNA Replication as a Source of DNA Damage

From Molecules to Human Health


30 Sep 2014 - 03 Oct 2014

El Jadida, Morocco

Chairs

Ian Hickson
University of Copenhagen
Oscar Fernandez-Capetillo
Spanish National Cancer Research Centre

Grants

DNA Replication as a Source of DNA Damage

From Molecules to Human Health


30 Sep 2014 - 03 Oct 2014

El Jadida, Morocco

Chairs

Ian Hickson
University of Copenhagen
Oscar Fernandez-Capetillo
Spanish National Cancer Research Centre

Supported By

Diamond
If you're interested in sponsoring this conference please contact us.

DNA Replication as a Source of DNA Damage

From Molecules to Human Health


30 Sep 2014 - 03 Oct 2014

El Jadida, Morocco

Chairs

Ian Hickson
University of Copenhagen
Oscar Fernandez-Capetillo
Spanish National Cancer Research Centre

Venue

Mazagan Beach Resort

Relax in the warm Moroccan sun at the Mazagan Beach Resort, a truly beautiful hotel situated along the coast with stunning panoramic views across the Atlantic Ocean. The resort combines traditional Moroccan culture with a modern twist creating an unforgettable conference experience for all.

The resort covers over 250 hectares offering an amazing array of activities and entertainment for delegates to choose from during their free time at the conference.

Throughout your stay delegates will enjoy a buffet feast for breakfast, lunch and dinner. During each meal delegates are entitled to selected beverages and 1 glass of house wine during dinner. The themed Moroccan Gala Night takes place on the third evening of the conference with a mouth-watering feast of local cuisine, an open bar and live performing band.  We welcome all delegates and their accompanying persons to the Gala Night – a truly fun filled night not to be missed!

Hotel Facilities

  • Beach
  • Resort Swimming Pool
  • Fitness Centre
  • Wellness Spa
  • Complimentary WI-FI in guestrooms and conference areas

Venue Rating

Currency

US Dollar (USD)

Address

Nearest Airport

Mohammed V International Airport (CMN)

Location

Morocco has over 2000miles of unspoilt sandy beaches, more than 300 days of sunshine per year and with its warm, friendly, hospitable people and delicious cuisine Morocco creates a perfect and unique location to hold a conference! Morocco is an ethnically diverse country with a rich culture and history. The region offers something for everyone, whether you like exploring the old winding medinas of its cities and towns, strolling along the stunning beaches, hiking the temperate peaks of the Rif mountain range or tasting some of the countries diversified cuisine.

Not far from the Mazagan Beach Resort is the Portuguese City of Mazagan, now known as El Jadida. It is one of the early settlements of the Portuguese explorers in West Africa on the route to India - it is an outstanding example of the interchange of influences between European and Moroccan cultures, well reflected in architecture, technology, and town planning. Popular sites include; The Municipal Theater of El Jadida, The Portuguese Cistern, The Canons and the Fortress and The Old Port. El Jadida is definitely a city worth visiting during your stay.

 

Supported By

Diamond
If you're interested in sponsoring this conference please contact us.

DNA Replication as a Source of DNA Damage

From Molecules to Human Health


30 Sep 2014 - 03 Oct 2014

El Jadida, Morocco

Chairs

Ian Hickson
University of Copenhagen
Oscar Fernandez-Capetillo
Spanish National Cancer Research Centre

Transportation

Travel Details

Mohammed V International Airport is Morocco’s busiest airport with regular direct flights from the US, Europe and Far East on a daily basis. Mohammed V International Airport is located just 60miles from the Mazagan Beach Resort and we recommened booking your transportation through the hotel. Contact details can be found below. 

Airport Transfers (Complimentary Hotel Shuttle)

**The free shuttle is extremely popular and is booked very quickly so please be advised that this service is not always available. 

Airport Transfers (Private)

To make an enquiry or booking (individual/group), please contact the Mazagan Beach Resort hotel and quote the group name ‘Fusion’ along with your hotel reservation number during your initial communications.

Email:  yassine.benjelloun@mazaganbeachresort.com (Yassine Benjelloun)

Private Airport Transfers - Provided by the Hotel.
(Prices per vehicle, per way)

2-3 seated car (Skoda): MAD 1050
2-3 seated car (A6 Mercedes Class E): 2100
2-3 seated car (Mercedes Class S 350 or Range Rover): 3255
6 seated van (Mercedes Viano): MAD 1050

Supported By

Diamond
If you're interested in sponsoring this conference please contact us.

DNA Replication as a Source of DNA Damage

From Molecules to Human Health


30 Sep 2014 - 03 Oct 2014

El Jadida, Morocco

Chairs

Ian Hickson
University of Copenhagen
Oscar Fernandez-Capetillo
Spanish National Cancer Research Centre

Local Activities

There is a wide variety of leisure and sports activities at the Mazagan. These are an ideal way to have fun and relax while enjoying the beautiful climate of the region of El Jadida and discovering the beautiful resort’s treasures during your free time within the conference schedule.

Please find below a few tours and excursions that are available during your stay. Should you have a group of 4 or more persons wishing to participate, then the following tours are available. However, if you wish to book completely independently, the cost is as indicated.

Casablanca

MAD 1000 (per person for 4 or more persons)
MAD 4000 (for independent tour - 3 persons or less)

Departure from Mazagan: 10:00
Arrival Back at Mazagan: Approximately 18:15

Casablanca is Morocco’s largest city and a world renowned centre for trade. Start with a visit to the central market, a massive kaleidoscope of colours and home of hundreds of stalls brimming with locally grown flowers, spices, vegetables, meats and all kinds of seafood as well as handicrafts. Continue to the new Medina of Casablanca and the Habous Quarter with its attractive Arab-Islamic architecture and admire the impressive facade of the Royal Palace.
You will also have the opportunity to visit the famous Hassan II great Mosque. A great architectural masterpiece, this is the world’s largest religious monument after Mecca and its minaret is the tallest. A truly memorable experience!

The rate includes transfers + lunch + guide + monuments’ entrance fees
Minimum 04 Persons / Max. 90 Persons

Imperial Rabat

MAD 1200 (per person for 4 or more persons)
MAD 4800  (for independent tour - 3 persons or less)

Rabat is an attractive city of domes and minarets, sweeping terraces, wide avenues and green spaces. Do not miss the picturesque Oudaia Kasbah, the Medina, the Hassan Tower and the mausoleum of Mohamed V, and the Chellah.

09:00 : Departure from Mazagan
11:15 : Arrival in Rabat
11:30 : Visit of the Royal Palace
12:00 : Chellah Site
12:45 : Lunch
14:30 : Tour Hassan Mosque
15:15 : Mausoleum Mohammed V
16:00 : Oudayas Site
16:30 : Rue des consuls
17:00 : Departure to Mazagan

The rate includes transfers + guide + monuments’ entrance fees
Minimum 04 Persons / Max. 90 Persons

If you would prefer to book a tour independently or enquire regarding alternative excursions available then please contact Yassime, details below, who will be happy to advise and assist with your booking.

For further information or to book a tour, excursion or activity please contact Yassine Benjelloun (Conference Services Manager) at the Mazagan yassine.benjelloun@MazaganBeachResort.com or alternatively you may make your booking once in resort, subject to availability.

The Mazagan also offers many sports and leisure activities including:
Windsurfing
Nordic Walking
Beach Volley
Paintball
Horse Riding
Tennis
Golf
Quad Biking
Karting

Full details can be found on the hotel website: http://www.mazaganbeachresort.com/activities/sportsandleisure.aspx

Please see below transportation prices (max 7 persons, price per person, per way) should you wish to arrange an independent trip to some of the local culture and tourist attractions in and around El Jadida:

El Jadida – MAD157.50
Casa Town – MAD1,050
Rabat – MAD2,625
Marrakech – MAD3,675
Agadir – MAD7,350
Fes – MAD4,725

*Transportation should be booked at the Concierge desk at the Mazagan

**All individual tours and excursions (not the Group Tours) should be arranged at the Leisure Desk at the Mazagan

The above information will also be available along with your welcome pack which is emailed to you shortly before the conference begins. 

Supported By

Diamond
If you're interested in sponsoring this conference please contact us.

DNA Replication as a Source of DNA Damage

From Molecules to Human Health


30 Sep 2014 - 03 Oct 2014

El Jadida, Morocco

Chairs

Ian Hickson
University of Copenhagen
Oscar Fernandez-Capetillo
Spanish National Cancer Research Centre

Group Activities

We have arranged 2 very exciting group tours for all DNA participants. Both tours are optional and should you wish to participate we would ask that you email sarah@fusion-conferences.com to confirm your participation no later than Monday 8th September as we are required to confirm numbers to the hotel by this date.

Details of the Group Tours are as follows:

Half Day Cultural Tour to El Jadida 

Wednesday 1st October 2014

  • 14:00: Departure from Mazagan
  • 14:20: Arrival at El Jadida and visit Portuguese City
  • 15:00: Visit the Portuguese Cistern
  • 15:30: Visit the Souks
  • 16:30: Departure to Mazagan

The cost for this tour is MAD350 per person and includes transfers + guide + monuments’ entrance fees. 

The Portuguese City of Mazagan (El Jadida), one of the first settlements created in Africa by Portuguese explorers on the route to India, bears outstanding witness to the exchange of influences between European and Moroccan cultures from the 16th to the 18th centuries. The surviving Portuguese buildings include the cistern and the Church of the Assumption, built in the Manueline style of late Gothic architecture. Very much worth a visit!

Full Day Group Tour to Marrakech

Monday 29th September 2014

  • 08:00 : Departure from  Mazagan
  • 11:00 : Arrival  at Marrakech
  • 11:10 : Visit of the Médina : Bahia Castle and  Saadiens  Tombs
  • 13:30 : Lunch
  • 15:00 : Visit of the souk and Jamaa El Fna Square
  • 18:00 : Departure to Mazagan

The cost for this tour is MAD1000 per person and includes transfers + lunch + guide + monuments’ entrance fees.

The southern Moroccan city of Marrakech was founded in 1070 and was considered an important political and cultural center in the western Muslim world. This captivating city is the most popular destination in all of Morocco. With its lively people, colourful marketplaces, impressive monuments, and religious sites, Marrakech is a feast for the eyes and the senses. Begin your tour with a photo opportunity at the spectacular Koutoubia Minaret, the largest mosque in Marrakech. Followed by a visit to the grounds of Bahia Place built between 1894 and 1900 with its lavish decoration and learn the fascinating history contained within the palace walls. Stroll through the old walled town of Medina and visit the open-air markets known as souks. These large trading venues brim with the most extraordinary array of goods you'll find anywhere in Morocco. Continue on to the city's most energetic spot, ironically called Djemaa-el-F'na, which means "Assembly of the Dead." This large, open square is home to snake charmers, street performers, soothsayers and spice vendors. You'll feel as if you've stepped right out of the pages of the Arabian Nights!

**Please note that once we have confirmed your participation for any of the above tours, the hotel will make a charge to your room upon check-in. This is a non-refundable fee should you later change your mind or not participate in the tour.

Supported By

Diamond
If you're interested in sponsoring this conference please contact us.

DNA Replication as a Source of DNA Damage

From Molecules to Human Health


30 Sep 2014 - 03 Oct 2014

El Jadida, Morocco

Chairs

Ian Hickson
University of Copenhagen
Oscar Fernandez-Capetillo
Spanish National Cancer Research Centre

Childcare

Supported By

Diamond
If you're interested in sponsoring this conference please contact us.

DNA Replication as a Source of DNA Damage

From Molecules to Human Health


30 Sep 2014 - 03 Oct 2014

El Jadida, Morocco

Chairs

Ian Hickson
University of Copenhagen
Oscar Fernandez-Capetillo
Spanish National Cancer Research Centre

Oral Presenters

A Fusion Conference offers all participants the opportunity to present their current research and findings in a number of different ways. Once registered for the conference you will be able to submit your abstract online and monitor the status through your Fusion account. Please use the abstract template provided and ensure your abstract is no longer than one page in length. Any abstracts exceeding this size may be cut short during print.

Oral Presentations

We have a number of oral opportunities available at this meeting. To be considered for an oral presentation, please submit your abstract within the 'Talk Deadline'. Please check the conference programme carefully to note your presentation time (inclusive of Q&A) should you be accepted for an oral presentation.

We recommend you check our website regularly as the conference approaches as regular programme updates will be released under the ‘Programme’ tab on the conference page.

If you have prepared some slides to compliment your presentation please ensure you bring these with you on a USB or portable file saving device.

Those presenting on the first day, please email your slides to us so we can have everything prepared and ready for the first session. Please email your slides to:powerpoint@fusion-conferences.com

Flash Presentations

The Flash Session lasts up to 45minutes. This time is evenly divided between all the Flash Presentations that are accepted so your allocated time can range from 3-5 minutes, depending on popularity. The flash session is an extension of the Poster Session and is designed to offer a select few the opportunity to present orally their poster in a more formal, group setting.
To be considered for a flash presentation, please submit your abstract within the 'Talk Deadline'. Abstracts submitted after the 'Talk Deadline' may not be accepted.

Please note, the exact length of your presentation will be noted on the conference programme under the ‘Flash Session’.

At the Conference

On the day of your presentation please make yourself known to the AV team who will be available in the conference room. They will ensure they have everything they need, including your presentation slides or aides. If you have any animations or videos we do advise to run through the presentation with the AV tech just to make sure everything is compatible. We also advise that all speakers make themselves known to the AV tech in the conference room immediately before your session beings. The AV tech will apply your microphone and provide a laser pointer should you have a complimenting presentation. Please note, speakers are not permitted to use their individual laptops, our AV tech will have a master laptop for you to run your presentation from. If you have any questions, please don’t hesitate to approach our AV tech or a member of the Fusion team. We are here to help!

We would like to ask all speakers to adhere to their time slots and respect their fellow presenters. A visual traffic light aide will be available to warn presenters as their time slot decreases. 

Download Abstract Template

Supported By

Diamond
If you're interested in sponsoring this conference please contact us.

DNA Replication as a Source of DNA Damage

From Molecules to Human Health


30 Sep 2014 - 03 Oct 2014

El Jadida, Morocco

Chairs

Ian Hickson
University of Copenhagen
Oscar Fernandez-Capetillo
Spanish National Cancer Research Centre

Posters

** Travel bursaries will be awarded to the best poster presenters.**

A Fusion Conference offers all participants the opportunity to present their current research and findings in a number of different ways. Once registered for the conference you will be able to submit your abstract online and monitor the status through your Fusion account. Please use the abstract template provided and ensure your abstract is no longer than one page in length. Any abstracts exceeding this size may be cut short during print.

Poster Presentations

To be considered to present a poster, please submit your abstract within the ‘Poster Deadline’. Please check the conference programme carefully to note the poster session date and time.

Our poster boards can accommodate a maximum poster size of A0 (1189H x 841W mm), portrait in orientation only. Posters exceeding this size may not fit on the poster boards provided and therefore you will be unable to present your poster, so please kindly keep to these measurements.

During registration at the conference, if you are presenting a poster please request a poster number from the registration desk. Please do not put up your poster without notifying a member of the Fusion team. Certain adhesive agents are not permitted at some venues therefore; Fusion will be the sole provider of all poster fixings.

At the Conference

Upon arrival at the conference you can put up your poster from registration with the help of the Fusion team. Your poster can remain on display for the entire duration of the conference and we ask that you take down your poster on the final day of the meeting. The poster sessions is usually scheduled on Day 2, but please check the official programme for exact timings. Refreshments will be provided and awards will be given to the best poster displays.

Download Abstract Template

Supported By

Diamond
If you're interested in sponsoring this conference please contact us.

DNA Replication as a Source of DNA Damage

From Molecules to Human Health


30 Sep 2014 - 03 Oct 2014

El Jadida, Morocco

Chairs

Ian Hickson
University of Copenhagen
Oscar Fernandez-Capetillo
Spanish National Cancer Research Centre

Conference History

30 Sep 2014, 03 Oct 2014

DNA Replication as a Source of DNA Damage

From Molecules to Human Health

Mazagan Beach Resort, El Jadida, Morocco

The maintenance of genome integrity is critical for the suppression of cancer and premature ageing. Only recently has it become appreciated that DNA replication stress is a crucial driver of genomic instability. The timely progression of replisome...

More Information

03 Jul 2017, 06 Jul 2017

2nd DNA Replication as a Source of DNA Damage Conference

From Molecules to Human Health

Sheraton Roma Hotel & Conference Center, Rome, Italy

The maintenance of genome integrity is critical for the suppression of cancer and premature ageing. Only recently has it become appreciated that DNA replication stress is a crucial driver of genomic instability. The timely progression of replisome...

More Information

14 Oct 2023, 17 Oct 2023

3rd Chromosomal Instability as a Driver of Human Disease Conference

#CIDHD23

Sun Gardens Dubrovnik, Dubrovnik, Croatia

All spaces for this conference have been filled and so we have had to close registration before the deadline. If you would like to be added to our wait list, please contact

More Information

07 Oct 2025, 10 Oct 2025

4th Chromosomal Instability as a Driver of Human Disease Conference

#CIDHD25

Hilton Malta, St. Julians, Malta

The maintenance of genome integrity is critical for the suppression of several pathological disorders in humans, including cancer, infertility premature ageing, and neurodegeneration. Destabilization of the genome can occur as a result of several ...

More Information

Supported By

Diamond
If you're interested in sponsoring this conference please contact us.

DNA Replication as a Source of DNA Damage

From Molecules to Human Health


30 Sep 2014 - 03 Oct 2014

El Jadida, Morocco

Chairs

Ian Hickson
University of Copenhagen
Oscar Fernandez-Capetillo
Spanish National Cancer Research Centre

Cant see images? See gallery on Flickr