Programme
THURSDAY 15TH FEBRUARY 2018 |
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15:00 – 16:00 |
Registration & Reception |
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15:00 – 15:45 |
Welcome Lunch |
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3D Genome, epigenetic inheritance and development |
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16:00 – 16:10 |
Opening Comments |
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16:10 – 16:40 |
Giacomo Cavalli |
3D GENOME ORGANIZATION AND POLYCOMB IN DEVELOPMENT AND EPIGENETIC INHERITANCE |
16:40 – 17:10 |
Victor Corces |
MECHANISMS OF TRANSGENERATIONAL INHERITANCE OF OBESITY PHENOTYPES |
17:10 – 17:40 |
Job Dekker |
FOLDING, UNFOLDING AND REFOLDING OF GENOMES |
17:40 – 18:10 |
Leonie Ringrose |
EPIGENETICS MEETS MATHEMATICS: THEORETICAL ANALYSIS OF BISTABILITY AND BIVALENT CHROMATIN IN THE POLYCOMB/TRITHORAX SYSTEM. |
18:10 – 18:40 |
Refreshments |
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18:40 – 19:10 |
Maria-Elena Torres-Padilla |
EPIGENETIC MECHANISMS IN EARLY MAMMALIAN DEVELOPMENT: SEARCHING FOR GLOBAL CHROMATIN TRENDS |
19:10 – 19:40 |
Anne Ferguson-Smith |
VARIABLE SILENCING OF THE REPEAT GENOME - IMPLICATIONS FOR NON-GENETIC INHERITANCE |
19:40 – 19:55 |
Anne-Marie Martinez |
COORDINATE REDEPLOYMENT OF PRC1 PROTEINS SUPPRESSES TUMOR FORMATION DURING DROSOPHILA DEVELOPMENT |
19:55 – 20:10 |
Marc Rehmsmeier - |
GENOME-WIDE PREDICTION OF FLY POLYCOMB/TRITHORAX RESPONSE ELEMENTS USING HIGH-THROUGHPUT EXPERIMENTAL DATA |
20:10 |
Dinner at Leisure |
FRIDAY 16TH FEBRUARY 2018 |
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07:00 – 08:45 |
Breakfast |
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Chromatin Complexes |
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09:00 – 09:15 |
Ruslan Sadreyev |
COOPERATION BETWEEN POLYCOMB AND TRITHORAX/COMPASS COMPLEXES AT BIVALENT PROMOTERS |
09:15 – 09:30 |
Claudia Gentile |
UNCOVERING THE ROLE OF POLYCOMB GROUP PROTEINS IN CHROMATIN ARCHITECTURE AND HOXA GENE REGULATION DURING LIMB DEVELOPMENT |
09:30 – 10:00 |
Alvaro Rada-Iglesias |
POLYCOMB PROTEINS AS TOPOLOGICAL FACILITATORS OF ENHANCER FUNCTION DURING NEURAL INDUCTION |
10:00 – 10:30 |
Adrian Bracken |
A NEW FAMILY OF VERTEBRATE-SPECIFIC POLYCOMB PROTEINS BALANCE PRC2 ACTIVITIES |
10:30 – 11:00 |
Refreshments & Group Photo |
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11:00 – 11:30 |
Luciano Di Croce |
ROLE OF POLYCOMB AND MLL COMPLEXES IN NUCLEAR ARCHITECTURE AND GENE REGULATION |
11:30 – 12:00 |
Iva Tchasovnikarova Massachusetts General Hospital |
NEUROPATHIC MUTATIONS IN MORC2 HYPERACTIVATE EPIGENETIC SILENCING BY THE HUSH COMPLEX |
12:00 – 16:30 |
Lunch at Leisure & Free Time |
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12:30 – 16:00 |
Snorkel Trip (TBC) |
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Chromatin, ncRNAs, Cell Fate and Disease |
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16:30 – 17:00 |
Tony Kouzarides |
MODIFICATIONS OF RNA: THEIR FUNCTION AND ROLE IN CANCER |
17:00 – 17:15 |
Ranjan Perera |
THE LONG NONCODING RNA SPRIGHTLY ACTS AS AN INTRA-NUCLEAR ORGANIZING HUB FOR PRE-mRNA MOLECULES |
17:15 – 17:45 |
Ali Shilatifard |
PRINCIPLES OF EPIGENETICS AND CHROMATIN IN DEVELOPMENT AND HUMAN DISEASE |
17:45 – 18:00 |
Gabriella Ficz |
NAÏVE HUMAN PLURIPOTENCY AS A MODEL FOR MECHANISMS OF ABERRANT DNA HYPERMETHYLATION IN CANCER |
18:00 – 18:30 |
Salvador Aznar Benitah |
EPIGENETIC MECHANISMS IN ADULT STEM CELLS FUNCTION |
18:30 – 20:00 |
Poster Session |
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20:00 |
Dinner at Leisure |
SATURDAY 17TH FEBRUARY 2018 |
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07:00 – 08:45 |
Breakfast |
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Heterochromatin and Chemical Biology Approaches |
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09:00 – 09:15 |
Paul Guilhamon |
CHROMATIN-BASED GBM CANCER STEM CELL CLASSIFICATION REVEALS THREE SUBTYPES SENSITIVE TO UNIQUE DRUG TREATMENTS |
09:15 – 09:45 |
Robert Schneider |
NOVEL PLAYERS IN CHROMATIN |
09:45 – 10:15 |
François Fuks |
TRANSCRIPTOME-WIDE DISTRIBUTION AND FUNCTION OF RNA MODIFICATIONS |
10:15 – 10:45 |
Refreshments |
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10:45 – 11:15 |
Jerome Déjardin |
TRANSCRIPTIONALLY ACTIVE HETEROCHROMATIN CONTROLS THE ACTIVATION OF ALTERNATIVE LENGTHENING OF TELOMERES |
11:15 – 11:45 |
Robert Sims |
UTILIZING CHEMICAL BIOLOGY TO IDENTIFY NOVEL STRATEGIES TARGETING HISTONE ACETYL SIGNALING IN CANCER |
11:45 – 12:00 |
Y. George Zheng |
BIOORTHOGONAL PROBES TO INTERROGATE PROTEIN LYSINE ACETYLATION AND ACYLATION |
12:00 – 12:15 |
Till Bartke |
DECODING CHROMATIN MODIFICATION STATES USING CHEMICAL BIOLOGY AND PROTEOMIC APPROACHES |
12:15 – 16:00 |
Lunch at Leisure & Free Time |
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Transcription and Chromatin Reprogramming |
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16:00 – 16:30 |
Ramin Shiekhattar |
INTEGRATOR REGULATES FIDELITY OF TERMINATION |
16:30 – 16:45 |
Michael Tolstorukov |
UNRAVELING INTRICATE RELATIONSHIP BETWEEN NUCLEOSOME OCCUPANCY AND CHROMATIN ACCESSIBILITY |
16:45 – 17:15 |
Cigall Kadoch |
STRUCTURE AND FUNCTION OF MAMMALIAN SWI/SNF (BAF) COMPLEXES IN HUMAN DISEASE |
17:15 – 17:30 |
Qin Yan |
KDM5 HISTONE DEMETHYLASES REGULATE ANTI-VIRAL AND ANTI-TUMOR IMMUNE RESPONSES THROUGH THE STING PATHWAY |
17:30 – 17:45 |
David Katz |
THE FUNCTION OF THE HISTONE DEMETHYLASE LSD1 IN CELL FATE AND TAU MEDIATED NEURODEGENERATION |
17:45 – 19:30 |
Poster Session |
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20:00 |
*Gala Dinner & Poster Awards* |
SUNDAY 18TH FEBRUARY 2018 |
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07:00 – 08:30 |
Breakfast |
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X-inactivation and Epigenetic Phenomena |
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09:00 – 09:15 |
Sundeep Kalantry |
RANDOM X-CHROMOSOME INACTIVATION BY THE HISTONE DEMETHYLASE SMCX/KDM5C |
09:15 – 09:30 |
Stefan Pinter |
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09:30 – 10:00 |
Roberto Bonasio |
EPIGENETIC REGULATION OF SOCIAL BEHAVIOR IN ANTS |
10:00 – 10:30 |
Refreshments |
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10:30 – 11:00 |
Michael Levine |
TRANS-CHROMOSOMAL ENHANCER-PROMOTER INTERACTIONS IN LIVING DROSOPHILA EMBRYOS |
11:00– 11:30 |
Sandra Peirò |
GENOME-WIDE MAPPING OF LAMIN B1 REVEALS THE EXISTENCE OF DYNAMIC AND FUNCTIONAL EUCHROMATIN LAMIN B1 DOMAINS (eLADs) DURING EPITHELIAL-TO-MESENCHYMAL TRANSITION (EMT) |
11:30 – 11:45 |
Closing Comments |