The fourth interventions in Aging Conference was held in Dubrovnik, after a 4-year gap due to the pandemic. The meeting covered an exciting selection of topics, including systems biology, genome maintenance and senescence, mitochondrial quality control, autophagy and proteostasis, regenerative medicine and reprogramming, and human aging. Research into aging is expanding rapidly, and there was a real sense of excitement at the new discoveries, the prospects for translating them into improved health during ageing, and the arrival of new research groups and institutes and growing interest from the private sector. The standard of the talks was excellent, and the trainees participated well in the discussions. The format of the Fusion meetings, with the opportunity to bring together scientists from diverse disciplines, the smallish number of delegates and the generous allocation of time for discussion, leads to unusually productive interactions. The poster session was well attended and lively, and an excellent chance for the trainees to discuss their own work. The new venue in Dubrovnik is delightful, and the Fusion team kept the proceedings impeccably organised.

A plethora of genetic, dietary and pharmacological interventions can extend healthy lifespan in laboratory animals, and can delay or ameliorate diverse aging-related diseases. Mechanisms of aging are conserved in evolution, and discoveries made in animals are informing our understanding of human aging. This raises the intriguing possibility of performing preventative medicine against chronic and age-related diseases, by targeting their main risk factor, namely aging. Important current challenges in the field are (1) to understand the downstream pathways by which longevity interventions can combat age-related loss of function and pathology, (2) to evaluate the impact of regenerative interventions and cellular reprogramming on age-related diseases, and (3) to translate the findings into the extension of human health span.  

This fourth meeting will continue to explore these topics, with particular emphasis on what we can learn from variation in the rate of ageing in the natural world, mitochondria, cellular senescence, biomarkers and epidemiology, immune aging and reprogramming and rejuvenation strategies.

Key Sessions

• Mitochondrial quality control and aging
• Ultra long lives and immortality
• Autophagy and proteostasis
• Regenerative interventions and cellular reprogramming
• Human ageing: biomarkers and cell senescence
• Microbiome and aging

Student Offer

Take advantage of this fantastic opportunity for students! Fully paying 'single' or 'shared' registrants can bring a student for only €882. Unfortunately, Postdocs are not eligible. Both registration packages include; accommodation for the 11, 12, 13 October 2023 (on a shared basis for students) and a food and beverage package for the conference period. Once registered, please contact Emily Meen to obtain a special registration link for your student. 

Confirmed Plenary Speakers

Yves Barral (ETH Zurich)
AGE-DEPENDENT ANEUPLOIDY, A STUDY CASE FOR DISSECTING THE MECHANISMS OF AGING
Ivan Dikic (Goethe University)
AGEING AND QUALITY CONTROL NETWORKS
Joan Mannick (Tornado Therapeutics)
USING mTOR INHIBITORS TO TARGET AGING BIOLOGY IN HUMANS
Wolf Reik (Altos Labs)
EPIGENETIC GENE REGULATION IN DEVELOPMENT AND AGEING
Masayo Takahashi (Vision Care Inc./ Ritsumeikan University)
FUTURE OF RETINAL REGENERATIVE MEDICINE

Confirmed Invited Speakers

Andreas Beyer (CECAD Cologne)
AGING-ASSOCIATED REWIRING OF TRANSCRIPTIONAL REGULATION
Seth Blackshaw (Johns Hopkins University)
Helena Cochemé (MRC London Institute of Medical Sciences)
REDOX SIGNALLING IN AGEING
Joris Deelen (Max Planck Institute for Biology of Aging)
UNRAVELLING THE SECRETS OF HEALTHY AGEING BY STUDYING THE GENETIC MAKE-UP OF LONG-LIVED INDIVIDUALS
Martin Denzel (Altos Labs)
TUNING mRNA TRANSLATION TO ENHANCE ROBUSTNESS AND INCREASE SURVIVAL
Judith Frydman (Stanford University)
Vera Gorbunova (University of Rochester)
MECHANISMS OF LONGEVITY
Shukry James Habib (Université de Lausanne)
REJUVENATING AND REPAIRING AGED BONES
Malene Hansen (Buck Institute for Research on Aging)
REGULATION OF AUTOPHAGY IN AGING AND DISEASE
Cole Haynes (University of Massachusetts)
ACTIVITIES THAT CONTRIBUTE MITOCHONDRIAL DYSFUNCTION IN AGING TISSUES
Leanne Jones (University of California, San Francisco)
Brian Kennedy (National University of Singapore)
Benoit Lehallier (Alkaheist)
PLASMA BASED THERAPEUTICS FOR DISEASES OF AGING
Morgan Levine (Altos Labs)
Pradeep Reddy (Altos Labs)
Anu Suomalainen (University of Helsinki)
Matthew Yousefzadeh (Columbia University)

We have a fantastic opportunity for Early Career Researchers, Post-docs and Students! We have limited places available at a highly discounted rate. Both registration packages include; accommodation for the 11, 12 & 13 Oct 2023 and a food and beverage package for the conference period.

Please send in an abstract for poster or short talk consideration, whether you wish to apply for shared or single accommodation, along with a few words as to why you would benefit from attending the conference to emily@fusion-conferences.com by 3rd May.

Shared Accommodation Offer (€539) - Accommodation on a shared basis. A room sharer can either be requested or you will be paired with another delegate of the same sex who has also requested to share.

Single Accommodation Offer (€780)  -  Accommodation on a single basis.