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- 4th Ubiquitin Function in Health & Disease Conference
Synopsis
We have reached a fascinating point in our research on the ubiquitin system’s function, physiology and roles in disease. The attachment of ubiquitin to a protein in the cytosol was first identified as a means to enable degradation of proteins in the cytosol by the proteasome. It was much later that it was discovered that the ubiquitin system fulfils another crucial cellular function: through the dynamics offered by ubiquitination and subsequent deubiquitination it gives a multitude of signalling pathways the required plasticity to initiate but also to limit their signalling output in an exquisitely controlled manner. Whereas certain signalling-related functions employ ubiquitin’s proteasome-targeting function, e.g. the activation of NF-kB following degradation of I-kB, most signalling-related functions of the ubiquitin system are mediated by different types of ubiquitin chains acting as scaffolds for the recruitment of signalling modules to protein complexes which serve as platforms for the triggering of specific signalling complexes.
Rather than discussing mainly structural aspects of the ubiquitin system, this conference is dedicated to the study of functional roles of the ubiquitin system, how it works to ensure normal signal transduction, what are the pathological consequences when it is perturbed and how can we harness our knowledge of the ubiquitin system therapeutically for more efficacious treatment of diseases with high unmet clinical need, including cancer, chronic inflammatory and autoimmune disorders as well as neurodegenerative diseases.
Importantly, this conference aims to become the go-to forum at which the most current and up-to-date therapeutic avenues that emerge from the study of the ubiquitin system will be presented and discussed.
A message from our Chairs... 'The field of ubiquitin biology and applications to clinical medicine is one of the most exciting topics in Biomedicine. With the realization that widely prescribed powerful immunomodulatory drugs (IMIDs) including thalidomide and its analogues lenalidomide and pomalidomide work by engaging ubiquitin mediated degradation of critical targets, the field has exploded. A PROTAC strategy (Proteolysis targeting chimera) is now underway at all major Biopharma enterprises to extend the lessons from the IMID field to specifically target unwanted proteins. The impact of the field is far reaching. Indeed, the Nobel Prize was recently given to researchers who worked out how hypoxia engages the ubiquitin system to regulate oxygen availability. The future for the field has never been brighter. Clear your calendars and come join what should be a most exciting conference in Portugal. It will focus on the myriad ways ubiquitin controls the signaling circuitry of life. If the regulation exerted by ubiquitin goes awry the consequences are devastating: it promulgates the pathology associated with inflammatory disease states, cancer and neurodegeneration.'
Target Audience
This conference will appeal to researchers who are particularly interested in the diverse functions of the ubiquitin system, rather than structural aspects of it, as well the way this system is involved in normal physiology in a whole range of pathologies that have been shown to be associated with abnormal ubiquitin signalling. Naturally this target profile will bring together researchers from both academia and the biotech/pharma industries who want to be on top of the most recent developments in this fascinating and fast developing field.
Learning Objectives
• To be on top of the field with regards to the diverse functions of the ubiquitin system.
• To comprehend how the ubiquitin system affects health and disease.
• To understand the therapeutic opportunities provided through our increased knowledge of ubiquitin’s functions.
• To learn which ubiquitin-related drug candidates are presently in preclinical and clinical development and in which clinical entities they are tested.
• To develop a sense for fruitful future research directions and therapeutic opportunities offered by the study of ubiquitin function.
Confirmed Speakers
Chairs
Programme
Registration Prices
| Ticket Type | Early Bird | Full Price |
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Single Choose this option if you will be attending the conference alone and wish to have your own private room. |
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Shared Choose this option if you wish to share with a colleague who is also attending the conference, or if you wish to be paired with another attendee of the same sex, or if you have an accompanying adult. |
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Student Choose this option if you are a student. Please note all students will be paired with another attendee of the same sex if a room sharer is not specified. If you wish to have your own room, please register under the 'Single' ticket option. |
Additional Prices
| Addition Type | Adult | Child |
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Additional Person This is the cost for an additional adult or child to join you in the same room, for the conference period. Additional guests are not permitted access to the conference. If you wish to extend your stay, please see our 'Extra Night' prices. |
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Extra Night Prices for extra nights apply per person, per night. |
All registration fees include 3 nights accommodation and meals during the conference period. Exact inclusions are detailed below.
What's Included in our Registration Fees?
Our registration fees are inclusive of the following at DolceCampo Real during the conference period only:
- Conference registration.
- 3 nights’ fixed accommodation (07, 08, 09 July 2026) on a single or shared basis.
- Buffet breakfast in Manjapão restaurant.
- Buffet lunch in Manjapão restaurant with soft drinks, beer and wine.
- Buffet dinner in Manjapão restaurant with soft drinks, beer and wine.
- BBQ Gala Dinner at Garden Terrace with soft drinks, beer and wine.
- Two drink vouchers during the poster session (can be exchanged for a glass of house wine, beer or soft drink).
- Daily coffee breaks.
- Complimentary WIFI throughout the hotel.
What's Included in our Accompanying Adult Fees?
Our accompanying adult fees are inclusive of the following at DolceCampo Real during the conference period only:
- 3 nights’ fixed accommodation (07, 08, 09 July 2026) on a shared basis with a conference participant.
- Buffet breakfast in Manjapão restaurant.
- Buffet lunch in Manjapão restaurant with soft drinks, beer and wine.
- Buffet dinner in Manjapão restaurant with soft drinks, beer and wine.
- BBQ Gala Dinner at Garden Terrace with soft drinks, beer and wine.
- Complimentary WIFI throughout the hotel.
Additional Information
Accompanying persons are not permitted access to the conference. Meals are only available during the times listed in the conference programme and accompanying guests must dine with the group.
What's Included in our Accompanying Child Fees?
Our accompanying child fees are inclusive of the following at DolceCampo Real during the conference period only:
- 3 nights’ fixed accommodation (07, 08, 09 July 2026) on a shared basis with the parent/s.
- Buffet breakfast in Manjapão restaurant.
- Buffet lunch with soft drinks in Manjapão restaurant.
- Buffet dinner with soft drinks in Manjapão restaurant.
- Gala Dinner with soft drinks at Garden Terrace.
- Complimentary WIFI throughout the hotel.
- A crib (0-3 years old) or roll out bed (4-17 years old).
Additional Information
Accompanying child fees are applicable for children aged 12-17 years.
Children aged 0-3 years stay free of charge and children aged 4-11 years will be charged a rate of €189.00, inclusive of the above package.
If your child is aged 0-11 years, please contact us so we can adjust the invoices relating to your child/children.
Please kindly ensure your child/children are supervised at all times during conference and related events. Childcare services may be available, please contact Rosie for further information.
What's Included in our Extra Night Fees?
- 1 night’s accommodation for 1 person.
- Buffet breakfast in Manjapão restaurant.
- Complimentary WIFI throughout the hotel.
Additional Information
Extra night child fees are applicable for children aged 12-17 years.
Children aged 0-11 years stay free of charge, inclusive of the above package.
If your child is aged 0-11 years, please contact us so we can adjust the invoices relating to your child/children.
Prices and hotel availability are subject to change without notice.
Venue & Location
Dolce CampoReal Lisboa
The Dolce CampoReal Lisboa is nestled in the scenic region of Torres Vedras, just 30minutes from the city of Lisbon. Set among the rolling hills and vineyards in the countryside, the hotel offers a focused and peaceful environment for conference sessions, whilst still only a short drive away from the hustle and bustle of the city, so attendees can take advantage of all Lisbon has to offer during free time.
The venue has modern, flexible meeting spaces, and due to its smaller size, we are able to offer group dining experiences on each of the conference days, so ideas can continue to be exchanged in a relaxed and informal setting after sessions conclude. For those who need or wish to travel with family, a dedicated kids club and family friendly activities ensure you can balance both work and play.
Outside of sessions, the hotel itself boasts a golf course, tennis courts and wellness facilities for both relaxation and recreation, and the surrounding area is perfect for scenic hikes or nature walks. With the venue nestled in one of Portugal’s renowned wine regions, delegates often enjoy visiting local vineyards for a wine tasting experience during free time.
The blend of both professional and personal experiences make it the perfect setting to reconnect with colleagues, relax with family, and fuel productive conversations to drive research forward.
Hotel Facilities
- Complimentary Wi-Fi in guest rooms and throughout hotel and conference areas
- Indoor heated swimming pool
- Outdoor swimming pool with Jacuzzi
- Spa
- Gym
- Golf course
- 2 Tennis courts
General Information
Venue Rating
★ ★ ★ ★ ★
Currency
Euro (EUR)
Address
R. do Campo (Campo Real) 2565-770 Portugal
Nearest Airport
Lisbon Portela Airport
Location
The Dolce CampoReal Lisboa is nestled between the vineyards and the extraordinary landscape of the Socorro and Archeira Mountains.
Lisbon is only a short 30-minute drive away. The Portuguese capital is constantly recognised as one of the greatest cities in the world, a claim confirmed by the “Lonely Planet Guides", who named Lisbon one of the world’s top 10 cities. Lisbon in one of the world’s oldest cities, predating the likes of London, Rome and Paris by hundreds of years. Hillsides covered in tumbledown houses and a mix of baroque and neoclassical buildings, including cathedrals and palaces, make up Lisbon’s skyline. The city is a combination of old and new, with beautiful modern buildings constructed near renovated historical landmarks and ruins.
Transportation
Dolce CampoReal Lisboa, Torres Vedras is approximately a 30-minute journey from Lisbon Portela Airport.
Taxis
Taxis are available outside the airport, but we would strongly recommend you pre-book your airport transfer with one of the many private transfer companies that are available. The Dolce CampoReal Lisboa is located outside of the city zone and a pre-booked transfer will be a cheaper option than a taxi taken from the airport taxi rank.
Uber also operate in and around Lisbon and there are other Portuguese taxi-hailing apps such as Bolt, MyTaxi, TaxisLisboa and Coop Taxis, all offering reasonable rates.
Pre-booked Airport Transfers
Should you wish to pre-book a taxi transfer from the airport, please find below details of a transportation provider who is aware of our groups. Please contact the supplier directly via email with any queries or booking requests and use ‘Fusion Conferences’ as a reference.
Prices
Up to 3 passengers - €75.00 EUR per transfer
4 - 7 passengers - €100.00 EUR per transfer
*please note, payment is required in advance to confirm your booking. Accepted payment methods include bank/wire transfer or credit card (via payment link).
Includes
- All taxes, fuel and tolls,
- Meet and greet inside the airport,
- Transportation in Audi or Mercedes,
- Courtesy water on board,
- One large or two small size bags per person.
Contact Information
Contact Name: Carlos Antunes
Contact Email: info@westshuttle.com
*please note all enquiries must be made with at least 48hrs notice. Thank you.
Transportation is the sole responsibility of the delegate. Please ensure you conduct your own research and double check your booking details ahead of your arrival. Fusion Conferences are unable to assist with or confirm transportation bookings due to insurance limitations. Thank you for your understanding.
Local Activities
There are various on-site activities available. These include:
- Indoor and 2 outdoor swimming pools
- Fitness centre, available 24h
- Tennis courts
- Donald Steel designed Golf Course – 18 holes Par 72
- Mandalay Wellness & Spa with 7 treatment rooms
- Kids Club – The hotel will provide details of daily activities for children
- Center “Clube Aventura” for outdoor activities such as Giant Balls, Aquaball, Stand Up Paddle, Archery, Slackline, Water Slide
**Please note, there may be a charge to participate in some of the above activities.
Should you have time to venture off-site, the Oeste Region and Torres Vedras have a distinctive cultural heritage, rich history, 20 km of coastal area, and a commitment to environmental awareness, accessibility and biodiversity. Below are a few suggestions:
- Monastery of Alcobaça, a UNESCO World Heritage site
- Historical route of the lines of Torres Vedras
- Day trip to Óbidos
- Royal Palace and Convent of Mafra
- Tapada Nacional de Mafra
- Mountain biking along the Santa Cruz to Torres Vedras Loop
- Birdwatching at the Tajus Estuary Nature Reserve
- Jeep tours in and around Torres Verdras
Submitting an Abstract
There are several presentation opportunities available at this meeting, in both talk and poster form. To be considered for either option, please register for the conference, upload your abstract when prompted to do so, and select your preferred presentation method. Once submitted, you will be able to monitor the status of your abstract through your Fusion account. You will also receive an email to confirm the outcome of your abstract review.
If you are unable to register for the conference for any reason, but still wish to submit an abstract for consideration, please email the Conference Manager directly.
Please use the abstract template provided (see below) and ensure your abstract is no longer than one page in length.
Note: talk slots are limited for each conference, and we often receive more submissions than spaces available. If your talk submission is unsuccessful on this occasion, your abstract will automatically be considered for a poster presentation as an alternative.
Accepted for a Short Talk
If you are accepted for a Short Talk, we recommend you check our website regularly as the conference approaches for programme updates, these will be released under the ‘Programme’ tab in the navigation panel to the left.
On the day of your presentation please make yourself known to our AV technician who will be present in the conference room. We advise running through your presentation at least 30 minutes prior to your session commencing to ensure your slides and any videos or animations appear as expected. We prefer our speakers to run their presentation from the master PC or Mac to ensure a smooth and timely transition between presenters, however, if you prefer to use your own laptop, please notify AV prior to the session. A HDMI cable is usually available on the podium to accommodate this.
Our AV technician will run through microphone options and provide a combined slide advancer and laser pointer ahead of your talk.
We ask all speakers to adhere to their time slots and respect their fellow presenters. A visual traffic light aide will be available to warn presenters as their time decreases, and our Session Chairs will assist with keeping everyone to time.
Please make sure your presentation adheres to the following guidelines:
Aspect Ratio: On Screen Show (16:9)
File Type: PPT, PPTS or Keynote format.
Accepted for a Poster Presentation
We recommend bringing your poster along with you to the conference as our venues do not have onsite printing facilities. If you wish to independently source local printing, please feel free to do so – the hotel address can be found under the ‘Venue’ tab if needed.
Our poster boards can accommodate a maximum poster size of A0 (1189H x 841W mm), portrait in orientation. Posters exceeding this size may not fit on the poster boards provided and therefore we may be unable to display your poster, so please kindly keep to these measurements.
Upon arrival to the conference, the Fusion team will give you instructions for displaying your poster. Your poster will remain on display for the duration of the conference, allowing presenters to take advantage of refreshment breaks and free time for valuable networking opportunities, in addition to the dedicated poster session.
Please check the programme and note the date and time of the poster session(s). Your poster will be judged during the poster session(s) and prizes will be awarded at the Gala Dinner.
Posters will be taken down by the Fusion team and can be collected on the final day of the conference.
If you are interested in this meeting but not yet ready to register, you can sign up for updates here and our team will keep you updated regarding deadline reminders and grant opportunities relating to this meeting only.
Conference Manager
Rosie Johnson
Need some help? Chat to the Fusion team today
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