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3^rd Interventions in Aging Conference

Past Conference

3^rd Interventions in Aging Conference

Date

03 Mar - 06 Mar 2019

Location

Nassau, Bahamas

Linda Partridge

University College London
Brian Kennedy

Yong Loo Lin School of Medicine, National University Singapore

Early Bird - Expired • Talk Submission - Expired • Poster Submission - Expired • Registration & Payment Deadline - Expired

3^rd Interventions in Aging Conference

03 Mar - 06 Mar 2019 • Nassau, Bahamas

Conference Manager

Meredith Willmott

Synopsis

A plethora of genetic, dietary and pharmacological interventions can extend healthy lifespan in laboratory animals, and can delay or ameliorate diverse aging-related diseases. Many of the signalling pathways involved are evolutionarily conserved, and are starting to be implicated in human aging. This raises the intriguing possibility of performing preventative medicine against the chronic diseases of our time by targeting the main risk factor for all of them, namely aging. Two important current challenges in the field are (1) to understand the downstream pathways by which longevity interventions combat age-related loss of function and pathology, and (2) to translate the findings into the extension of human healthspan.

This third meeting will continue to explore these topics, with particular emphasis on the systemic environment, mitochondria, biomarkers and frailty, immune aging and the protective effects of natural products.

For those interested, this meeting follows the Mitochondria: From Basic Biology to Mechanisms of Disease Conference, taking place from 27 February - 02 March 2019 at the same venue.

Student Offer

Take advantage of this fantastic opportunity for students! Register an academic at the standard rate of $1,922 and bring a student for only $850. Unfortunately, Postdocs are not eligible. Both registration packages include; accommodation for the 03, 04, 05 March 2019 (on a shared basis for students) and a 24hour all-inclusive food and beverage package for the conference period. Academic registrations must be completed by 14 December 2018. Once registered, please contact Meredith Willmott to obtain a special registration link for your student.

Confirmed Plenary Speakers:

Darren Baker (Mayo Clinic)
IMPLICATING SENESCENT CELLS TO NEURODEGENERATIVE PATHOLOGIES
Shin-ichiro Imai (Washington University in St. Louis)
Thomas Langer (Max Planck Institute)
PROTEOLYTIC CONTROL OF MITOCHONDRIAL PLASTICITY
Janet Lord (University of Birmingham)
PREVENTING AND OVERCOMING IMMUNESENESCENCE
Joan Mannick (resTORbio)
TORC1 INHIBITION AS AN IMMUNOTHERAPY TO DECREASE INFECTIONS IN THE ELDERLY
Dennis Villareal (Baylor College of Medicine)
LIFESTYLE INTERVENTIONS TO REVERSE FRAILTY IN OLDER ADULTS WITH OBESITY

Confirmed Invited Speakers:

Thiruma Arumugam (National University of Singapore)
INTERMITTENT METABOLIC SWITCHING AND BRAIN HEALTH
Bonnie Blomberg (University of Miami)
PROGRESS IN AGING AND IMMUNITY
Steven Braithwaite (Alkahest)
MULTIMODAL THERAPEUTICS FROM THE PLASMA PROTEOME FOR AGE-RELATED DISORDERS
Katrin Chua (Stanford University)
CHROMATIN REGULATION AND GENOME MAINTENANCE BY HUMAN SIRTUINS SIRT6 AND SIRT7
Kaare Christensen (University of Southern Denmark)
LONGEVITY ENRICHED FAMILIES. HOW DID THEY SUCCEED?
Peter Fedichev (GERO)
Vadim Gladyshev (Harvard Medical School)
Jan Gruber (Yale NUS College)
LEVERAGING PATHWAY SYNERGY FOR PHARMACOLOGICAL INTERVENTIONS TO EXTEND HEALHTY LIFESPAN
Vera Gorbunova (University of Rochester)
FROM COMPARATIVE BIOLOGY TO ANTI-AGING INTERVENTIONS
Jesús Gil (MRC London Institute of Medical Sciences)
Marcia Haigis (Harvard Medical School)
MITOCHONDRIAL METABOLISM AND AGING
Jackie Han (PICB Shanghai)
Gerald de Haan (European Research Institiute for the Biology of Ageing)
NEW GENES INVOLVED IN HEMATOPOIETIC STEM CELL AGING
Heinrich Jasper (Genentech)
AGE RELATED STEM CELL DYSFUNCTION IN BARRIER EPITHELIA - STRATEGIES FOR INTERVENTION
Dudley Lamming (University of Wisconsin)
THE REGULATION OF METABOLIC HEALTH AND LONGEVITY BY SPECIFIC DIETARY MACRONUTRIENTS
William Mair (Harvard T.H. Chan)
RNA SPLICING AND LONGEVITY
Darcie Moore (University of Wisconsin)
Richard Miller (University of Michigan)
THE MOUSE ITP: CURRENT PROGRESS AND PROJECTS or CAP-INDEPENDENT TRANSLATION OF SELECTIVE MRNAS IN LONG-LIVED MUTANT MICE
Nicolas Musi (UT Health, San Antionio)
Thomas Nystrom (University of Gothenburg)
HUNTING FOR GENES GENERATING CELLULAR AGE ASYMMETRY
Arlan Richardson (University of Oklahoma Health Science Center)
IS REDUCING NECROPTOSIS AN POTENTIAL INTERVENTION IN AGING?
Dave Schubert (Salk Institute)
GERONEUROPROTECTORS: EFFECTIVE GEROPROTECTORS FOR THE BRAIN
Thomas Weldon (Ponce de Leon Health, Inc)
PONCE DE LEON HEALTH
Kai Zhou (Buck Institute)

Target Audience

Basic scientists in the field of aging research using animal models.
Human researchers interested in biomarkers of aging
Clinical trials specialists in aging and associated diseases.
Scientists and other professionals developing aging interventions.
Investors looking to enter this new space
Educated public

Educational Need

The aging field encompasses a wide range of biology, involving many model organisms and, with respect to mammals, the involvement of many tissues. In addition, translational strategies to modify the rate of aging range from lifestyle change to drugs and, more recently stem cell-based therapeutics. As such, there is an abiding need to bring together scientists across diverse fields with the purpose of providing a clear overview of the state of basic research in aging and the development of translational strategies. The goal is to create cross-fertilization between scientists in different areas, accelerating the development of interventions that extend human healthspan.

Confirmed Speakers

Chairs

Linda Partridge

Director Max Planck Institute for Biology of Ageing, Director Institute of Healthy Ageing, and GEE, University College London

Brian Kennedy

Professor, Yong Loo Lin School of Medicine, National University Singapore

Plenary Speakers

Janet Lord

Director of the Institute of Inlammation and Ageing, Birmingham University

Darren Baker

Senior Associate Consultant I, Mayo Clinic

Dennis Villareal

Professor, Baylor College of Medicine

Thomas Langer

Director, Max-Planck-Institute for Biology of Ageing

Joan Mannick

Chief Medical Officer, resTORbio

Shin-ichiro Imai

Professor, Washington University School of Medicine

Invited Speakers

Dudley Lamming

Assistant Professor, University of Wisconsin-Madison

Kaare Christensen

Professor, University of Southern Denmark

Darcie Moore

Associate Professor, University of Wisconsin-Madison

David Schubert

professor, Salk Institute

William Mair

Associate Professor, Harvard University

Steven Braithwaite

CSO, Alkahest

Heinrich Jasper

Staff Scientist, Genentech, Inc.

Thiruma Arumugam

Associate Professor, National University of Singapore

Richard Miller

Professor, University of Michigan

Bonnie Blomberg

Professor, U Miami Miller School of Medicine

Gerald de Haan

Scientific Director, European Research Institute for the Biology of Ageing

Chuankai (Kai) Zhou

Fellow, Buck Institute for Research on Agin

Arlan Richardson

Professor, University of Oklahoma Health Sciences Center

Vadim Gladyshev

Principal Investigator, Harvard Medical School

Vera Gorbunova

Professor, University of Rochester

Thomas Weldon

Chairman & CEO, Ponce de Leon Health, Inc

Marcia Haigis

Associate Professor, Harvard Medical School

Peter Fedichev

Founder & Chief Science Officer, Gero LLC

Nicolas Musi, MD

Professor of Medicine, Director of the Barshop Institute, UT Health Science SA

Jan Gruber

Assistant Professor, Yale-NUS

Matt Kaeberlein

Chief Science Officer, Optispan

Jesus Gil

Professor, MRC London Institute of Medical Sciences

Programme

SUNDAY 03^RD MARCH 2019
14:00 – 15:00	Registration & Welcome Reception
Translational Gerontology Session Chair: Linda Partridge
15:00 – 15:10	Opening Comments
15:10 – 15:45	Joan Mannick resTORbio	TORC1 INHIBITION AS AN IMMUNOTHERAPY TO DECREASE INFECTIONS IN THE ELDERLY
15:45 – 16:10	Steven Braithwaite Alkahest	MULTIMODAL THERAPEUTICS FROM THE PLASMA PROTEOME FOR AGE-RELATED DISORDERS
16:10 – 16:35	Matt Kaeberlein University of Washington	TARGETING HALLMARKS OF AGING WITH RAPAMYCIN: NEW INSIGHTS INTO MECHANISM AND OPPORTUNITIES FOR CLINICAL INTERVENTION
16:35 – 17:00	Jan Gruber Yale NUS College	LEVERAGING PATHWAY SYNERGY FOR PHARMACOLOGICAL INTERVENTIONS TO EXTEND HEALHTY LIFESPAN
17:00 – 17:45	Refreshments
Immunity and Aging Session Chair: Joan Mannick
17:45 – 18:10	Thomas Weldon Ponce de Leon Health, Inc	PONCE DE LEON HEALTH
18:10 – 18:35	Bonnie Blomberg University of Miami	PROGRESS IN AGING AND IMMUNITY
18:35 – 19:10	Janet Lord University of Birmingham	PREVENTING AND OVERCOMING IMMUNESENESCENCE
19:10 – 19:35	Vera Gorbunova University of Rochester	FROM COMPARATIVE BIOLOGY TO ANTI-AGING INTERVENTIONS
19:35 – 20:00	Meet the Poster Presenters I Moderators: Linda Partridge & Brian Kennedy
19:35 – 20:00	Accompanying Guests Pre-Dinner Welcome Drinks
20:00	Dinner

MONDAY 04^TH MARCH 2019
07:00 – 09:00	Buffet Breakfast at The Market Place
Human Aging Session Chair: Arlan Richardson
09:00 – 09:35	Dennis Villareal Baylor College of Medicine	LIFESTYLE INTERVENTIONS TO REVERSE FRAILTY IN OLDER ADULTS WITH OBESITY
09:35 – 10:00	David Schubert Salk Institute	GERONEUROPROTECTORS: EFFECTIVE GEROPROTECTORS FOR THE BRAIN
10:00 – 10:25	Peter Fedichev GERO LLC	LONGITUDINAL ANALYSIS OF AGING TRAJECTORIES REVEALS INTERPLAY BETWEEN AGING, FRAILTY AND RESILIENCE, PROVIDES EVIDENCE OF THE LIMITING LIFESPAN
10:25 – 11:10	Group Photo, Refreshments & Poster Viewing
11:10 – 11:35	Kaare Christensen University of Southern Denmark	LONGEVITY ENRICHED FAMILIES. HOW DID THEY SUCCEED?
11:35 – 12:00	Nicolas Musi UT Health Science, San Antonio	ACARBOSE AS A LIFESPAN AND HEALTHSPAN-EXTENDING DRUG
12:00 – 16:30	Lunch at Leisure & Free Time
12:45 – 16:00	Group Activity: Snorkel Trip (sign-ups required in advance)
Aging in Mice Session Chair: Janet Lord
16:30 – 17:05	Shin-ichiro Imai Washington University School of Medicine	NAD WORLD 3.0: THE IMPORTANCE OF ENAMPT AND THE NMN TRANSPORTER IN MAMMALIAN AGING/LONGEVITY CONTROL
17:05 – 17:30	Arlan Richardson University of Oklahoma Health Science Center	IS REDUCING NECROPTOSIS AN POTENTIAL INTERVENTION IN AGING?
17:30 – 17:55	Richard Miller University of Michigan	THE NIA ITP: PROGRESS AND PLANS
17:55 – 18:10	Tobias Nespital Max Planck Institute for Biology of Ageing	TESTING THE EFFECT OF TRAMETINIB ON MOUSE LIFESPAN AND HEALTHSPAN
18:10 – 18:25	Paul Fox Cleveland Clinic	A NOVEL S6K1 PHOSPHO-FORM TARGETS EPRS AND INFLUENCES ADIPOSITY AND LIFESPAN IN MICE
18:25 – 18:50	Marcia Haigis Harvard Medical School	MITOCHONDRIAL METABOLISM AND AGING
18:50 – 20:00	Poster Session & Refreshments
20:00	Dinner

TUESDAY 05^TH MARCH 2019
07:00 – 09:00	Buffet Breakfast at The Market Place
Mitochondri a and Aging Session Chair: Gerald de Haan
09:00 – 09:15	Keshav Singh The University of Alabama at Birmingham	REVERSING WRINKLED SKIN AND LOST HAIR IN MICE BY RESTORING MITOCHONDRIAL FUNCTION
09:15 – 09:30	Pamela Maher Salk Institute for Biological Studies	A NOVEL ANTI-AGING COMPOUND FOR THE TREATMENT OF ALZHEIMER'S DISEASE
09:30 – 09:55	Kai Zhou Buck Institute for Research on Aging	MITOCHONDRIAL FACTORS REGULATE THE FORMATION AND DISSOLUTION OF PROTEIN AGGREGATES
09:55 – 10:30	Thomas Langer Max Planck Institute	PROTEOLYTIC CONTROL OF MITOCHONDRIAL PLASTICITY
10:30 – 11:15	Refreshments & Poster Viewing
11:15 – 11:30	Martin Denzel Max Planck Institute for Biology of Ageing	INHIBITION OF THE INTEGRATED STRESS RESPONSE EXTENDS LIFESPAN
11:30 – 11:45	Franziska Ottens University of Cologne, CECAD Research Center	OLFACTION REGULATES ORGANISMAL PROTEOSTASIS AND LONGEVITY VIA MICRORNA-DEPENDENT SIGNALING
11:45 – 17:00	Lunch at Leisure & Free Time
Cellular Senescence Session Chair: Shin-ichiro Imai
17:00 – 17:25	Darren Baker Mayo Clinic	IMPLICATING SENESCENT CELLS TO NEURODEGENERATIVE PATHOLOGIES
17:25 – 17:50	Jesús Gil MRC London Institute of Medical Sciences
17:50 – 18:15	Gerald de Haan European Research Institute for the Biology of Ageing	NEOGENIN-1: IDENTIFICATION OF A NOVEL RECEPTOR ASSOCIATED WITH HEMATOPOIETIC STEM CELL AGING
18:15 – 19:00	Refreshments & Poster Viewing
19:00 – 19:25	Darcie Moore University of Wisconsin-Madison	THE INTERMEDIATE FILAMENT VIMENTIN MEDIATES RECOVERY FROM A LOSS OF PROTEOSTASIS IN NEURAL STEM CELLS
19:25 – 19:40	Emma Bolderson Queensland University of Technology	THE ROLE OF BANF1 IN THE REPAIR OF OXIDATIVE DNA DAMAGE
19:40 – 19:55	Alyona Keder University College London	DECIPHERING AUDITORY AGEING: LESSONS FROM DROSOPHILA
20:00	Gala Dinner & Poster Awards

WEDNESDAY 06^TH MARCH 2019
07:00 – 09:00	Buffet Breakfast at The Market Place
Metabolism and Aging Session Chair: Heinrich Jasper
09:00 – 09:25	Dudley Lamming University of Wisconsin-Madison	THE REGULATION OF METABOLIC HEALTH AND LONGEVITY BY SPECIFIC DIETARY MACRONUTRIENTS
09:25 – 09:50	Gavin Ng National University of Singapore	DISSECTING EPIGENETIC MECHANISM OF INTERMITTENT FASTING
09:50 – 10:20	Refreshments
Longevity Pathways Session Chair: Brian Kennedy
10:20 – 10:45	Heinrich Jasper Genentech	AGE RELATED STEM CELL DYSFUNCTION IN BARRIER EPITHELIA - STRATEGIES FOR INTERVENTION
10:45 – 11:10	Vadim Gladyshev Harvard Medical School	COMPARATIVE GENOMICS OF LIFESPAN CONTROL
11:10 – 11:35	Katrin Chua Stanford University	CHROMATIN REGULATION AND GENOME MAINTENANCE BY HUMAN SIRTUINS SIRT6 AND SIRT7
11:35 – 12:00	William Mair Harvard University	NOVEL MOLECULAR MECHANISMS LINKING RNA SPLICING AND LONGEVITY
12:00 – 12:15	Closing Comments

Supported by

Media Partners

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Venue & Location

Melia Nassau Beach All Inclusive

Overlooking one of the finest beaches in the world the Meliá Nassau Beach is surrounded by crystal blue waters and white sandy beaches. Located on the stunning Cable Beach, you are just a few minutes walk from the center, shops and restaurants. The beautiful Nassau Botanical Gardens are within easy reach (7km) and Lynden Pindling International Airport is situated only 9km away.

Throughout your stay delegates will enjoy a full meal plan, inclusive of beverages. Take your pick from Cilantro where you can experience the natural textures, aromas and flavors of Mexico, Nikkei, celebrated for its exquisite fusion of Japanese, Cantonese and Peruvian cuisine featuring a sushi bar and Teppanyaki tables, Estavida, an upbeat tapas lounge located in the hotel lobby serving innovative tapas and a wide selection of cocktails, Aqua, an A la carte restaurant specializing in exquisite, rustic Italian cuisine, The Market Place, where you will find an International buffet serving an array of exquisite dishes, O'Grille, an open air restaurant with fabulous views of the sea and pool serving casual beach fare and light bites and finally The Black Angus, a steakhouse featuring hip, contemporary jazz and modern decor, offering guests the finest quality prime cuts and the freshest ingredients.(This restaurant is not included in the all inclusive package, additional charges apply). The Gala Night takes place on the third evening of the conference with a mouth-watering feast of local cuisine, an open bar and amazing local entertainment. We welcome all delegates and their accompanying persons to the Gala Night – a truly fun filled night not to be missed!

Hotel Facilities

24 hour reception
Room service
3 heated outdoor pools
Complimentary resort wide Wi-Fi (guest rooms, throughout hotel, beach and conference areas)
24-hour Fitness Center
7 dining venues
4 bars.
non-motorised water sports

The Bahamas is formed by over 700 islands, keys and islets located in the Atlantic Ocean and renowned for its warm sunshine, mild climate, fine, white sandy beaches, turquoise, crystal clear water and friendly people, making this the perfect environment to relax and unwind in your free time during the conference.

General Information

Venue Rating

★ ★ ★ ★

Currency

US Dollar (USD)

Address

Nassau W Bay St. Nassau Bahamas

Nearest Airport

Lynden Pindling International Airport

Location

The Melia Nassau Beach All-Inclusive is located right on the stunning Cable Beach just a few minutes away from the airport and city center; Nearby in Downtown Nassau you can experience the flavours of new foods at local restaurants, shop 'til you drop at Straw market or take a trip through time at the Pirates Museum. The beautiful Nassau Botanical Gardens are close by and water enthusiasts can enjoy non-motorized water sports right on property.

Nassau is the capital of the Bahamas. It lies on the island of New Providence, with neighboring Paradise Island accessible via Nassau Harbor bridges. The city has a hilly landscape and is known for it's fabulous beaches as well as its offshore coral reefs, popular for diving and snorkeling. It retains many of its typical pastel-colored British colonial buildings, like the pink-hued Government House.

Media Partners

If you're interested in sponsoring this conference please contact us.

Conference Manager

Meredith Willmott

Need some help? Chat to the Fusion team today

As a family run business, our dedication runs deep. We’re committed to each other and, even more so, to every attendee’s experience, delivering a level of care and passion that’s truly unmatched.

Call us

+44 (0) 1638 555057

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3rd Interventions in Aging Conference

Synopsis

Student Offer

Confirmed Plenary Speakers:

Confirmed Invited Speakers:

Target Audience

Educational Need

Confirmed Speakers

Chairs

Plenary Speakers

Invited Speakers

Programme

SUNDAY 03RD MARCH 2019

MONDAY 04TH MARCH 2019

TUESDAY 05TH MARCH 2019

WEDNESDAY 06TH MARCH 2019

Supported by

Media Partners

Venue & Location

General Information

Location

Conference History

Media Partners

Need some help? Chat to the Fusion team today

Looking for forthcoming conferences?

3^rd Interventions in Aging Conference

SUNDAY 03^RD MARCH 2019

MONDAY 04^TH MARCH 2019

TUESDAY 05^TH MARCH 2019

WEDNESDAY 06^TH MARCH 2019